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B1W3X3 (GLMM_STRGG) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoglucosamine mutase
EC=5.4.2.10
Gene names
Name:glmM
Ordered Locus Names:SGR_2800
OrganismStreptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350) [Complete proteome] [HAMAP]
Taxonomic identifier455632 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces ›

Protein attributes

Sequence length452 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP-Rule MF_01554

Catalytic activity

Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP-Rule MF_01554

Cofactor

Binds 1 magnesium ion per subunit By similarity.

Post-translational modification

Activated by phosphorylation By similarity.

Sequence similarities

Belongs to the phosphohexose mutase family.

Ontologies

Keywords
   LigandMagnesium
Metal-binding
   Molecular functionIsomerase
   PTMPhosphoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcarbohydrate metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: HAMAP

phosphoglucosamine mutase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 452452Phosphoglucosamine mutase HAMAP-Rule MF_01554
PRO_1000201149

Sites

Active site1041Phosphoserine intermediate By similarity
Metal binding1041Magnesium; via phosphate group By similarity
Metal binding2461Magnesium By similarity
Metal binding2481Magnesium By similarity
Metal binding2501Magnesium By similarity

Amino acid modifications

Modified residue1041Phosphoserine By similarity

Sequences

Sequence LengthMass (Da)Tools
B1W3X3 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: 9E86D69B09681727

FASTA45246,795
        10         20         30         40         50         60 
MGRLFGTDGV RGVANADLTA ELALGLSVAA AHVLAEAGTF AGHRPTAVVG RDPRASGEFL 

        70         80         90        100        110        120 
EAAVVAGLAS AGVDVLRVGV LPTPAVAYLT GSLGADIGVM LSASHNAMPD NGVKFFARGG 

       130        140        150        160        170        180 
HKLADELEDR IETVYEQHRT GEPWSRPTGA GVGRVTDYTE GFDRYVAHLI GVLPNRLDGL 

       190        200        210        220        230        240 
KVVLDEAHGA AARVSPEAFA RAGAEVVTIG ADPDGLNIND GCGSTHLELL RAAVVEHGAD 

       250        260        270        280        290        300 
LGIAHDGDAD RCLAVDAAGE EVDGDQILAV LALAMRDAGQ LRKDTVVGTV MSNLGFKLAM 

       310        320        330        340        350        360 
EREGIRLVQT AVGDRYVLES MKAEGFALGG EQSGHVIVLD HATTGDGTLT GLMLAARVAA 

       370        380        390        400        410        420 
TGRSLAELAG VMQRLPQVLI NVPDVDKTRV NTSSELATAV VEAERELGEN GRVLLRQSGT 

       430        440        450 
EPLVRVMVEA ADIEQARAVA GRLADVVKSA LG

« Hide

References

[1]"Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350."
Ohnishi Y., Ishikawa J., Hara H., Suzuki H., Ikenoya M., Ikeda H., Yamashita A., Hattori M., Horinouchi S.
J. Bacteriol. 190:4050-4060(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JCM 4626 / NBRC 13350.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP009493 Genomic DNA. Translation: BAG19629.1.
RefSeqYP_001824312.1. NC_010572.1.

3D structure databases

ProteinModelPortalB1W3X3.
ModBaseSearch...

Protein-protein interaction databases

STRING455632.SGR_2800.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAG19629; BAG19629; SGR_2800.
GeneID6209846.
KEGGsgr:SGR_2800.
PATRIC23752131. VBIStrGri32265_2862.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1109.
HOGENOMHOG000268678.
KOK03431.
OMATLMSNMS.
ProtClustDBPRK14318.

Family and domain databases

Gene3D3.40.120.10. 3 hits.
HAMAPMF_01554_B. GlmM_B.
InterProIPR005844. A-D-PHexomutase_a/b/a-I.
IPR016055. A-D-PHexomutase_a/b/a-I/II/III.
IPR005845. A-D-PHexomutase_a/b/a-II.
IPR005846. A-D-PHexomutase_a/b/a-III.
IPR005843. A-D-PHexomutase_C.
IPR005841. Alpha-D-phosphohexomutase_SF.
IPR006352. GlmM.
[Graphical view]
PfamPF02878. PGM_PMM_I. 1 hit.
PF02879. PGM_PMM_II. 1 hit.
PF02880. PGM_PMM_III. 1 hit.
PF00408. PGM_PMM_IV. 1 hit.
[Graphical view]
PRINTSPR00509. PGMPMM.
SUPFAMSSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMsTIGR01455. glmM. 1 hit.
PROSITEPS00710. PGM_PMM. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGLMM_STRGG
AccessionPrimary (citable) accession number: B1W3X3
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: May 20, 2008
Last modified: May 1, 2013
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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