B1W3X0 (B1W3X0_STRGG) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Pantothenate kinase HAMAP MF_00215 RuleBase RU003530
EC=2.7.1.33 HAMAP MF_00215 RuleBase RU003530

Alternative name(s):
Pantothenic acid kinase HAMAP MF_00215

Gene names

Name:	coaA HAMAP MF_00215
Ordered Locus Names:	SGR_2797

Organism

Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350) [Complete proteome] [HAMAP]

Taxonomic identifier

455632 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length	331 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (R)-pantothenate = ADP + (R)-4'-phosphopantothenate. HAMAP MF_00215 RuleBase RU003530 SAAS SAAS004566
Pathway	Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5. HAMAP MF_00215 RuleBase RU003530 SAAS SAAS004566
Subcellular location	Cytoplasm By similarity HAMAP MF_00215 RuleBase RU003530 SAAS SAAS004566.
Sequence similarities	Belongs to the prokaryotic pantothenate kinase family. HAMAP MF_00215 RuleBase RU003530

Ontologies

Keywords
Biological process	Coenzyme A biosynthesis HAMAP MF_00215 RuleBase RU003530 SAAS SAAS004566
Cellular component	Cytoplasm HAMAP MF_00215 RuleBase RU003530 SAAS SAAS004566
Ligand	ATP-binding HAMAP MF_00215 RuleBase RU003528 SAAS SAAS004566 Nucleotide-binding
Molecular function	Kinase HAMAP MF_00215 RuleBase RU003528 SAAS SAAS004566 EMBL BAG19626.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme A biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP pantothenate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	109 – 116	8	ATP By similarity HAMAP MF_00215

Sequences

	Sequence		Length	Mass (Da)
	B1W3X0 [UniParc]. Last modified May 20, 2008. Version 1. Checksum: B9C078B0D8CC3BF6	FASTA	331	37,142
	10 20 30 40 50 60 MITSTARSPQ RRTEHAPTPY VDLSRDEWSA LRDKTPLPLT ADEVERLRGL GDVIDLDEVR 70 80 90 100 110 120 DVYLPLSRLL NLYVQATSGL RGALNTFLGD AGNGHGAQRG TPFVIGVAGS VAVGKSTSAR 130 140 150 160 170 180 ILQALLARWP EHPRVELVTT DGFLLPMKEL KARGLTSRKG FPESYDRRAL TRFVADIKAG 190 200 210 220 230 240 KDEVTAPVYS HLIYDIVPGE RLTVRRPDIL IVEGLNVLQP ALPGSDGRTR VGLADYFDFS 250 260 270 280 290 300 VYVDARAEDI ETWYLNRFRK LRATAFQDPS SYFRKYTQVS EEEALDYART MWRTINKPNL 310 320 330 LENVAPTRGR ATLVLRKGPD HKVQKLSLRK L

References

[1]

"Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350." Ohnishi Y., Ishikawa J., Hara H., Suzuki H., Ikenoya M., Ikeda H., Yamashita A., Hattori M., Horinouchi S. J. Bacteriol. 190:4050-4060(2008) [PubMed: 18375553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009493 Genomic DNA. Translation: BAG19626.1.
RefSeq	YP_001824309.1. NC_010572.1.
3D structure databases
ProteinModelPortal	B1W3X0.
SMR	B1W3X0. Positions 16-331.
ModBase	Search...
Protein-protein interaction databases
STRING	B1W3X0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6209123.
GenomeReviews	Gene locus SGR_2797 in contig AP009493_GR.
KEGG	sgr:SGR_2797.
PATRIC	23752125. VBIStrGri32265_2859.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG732538.
OMA	EVYLPLS.
ProtClustDB	PRK05439.
Family and domain databases
HAMAP	MF_00215. Pantothen_kinase_1. [Tree]
InterPro	IPR004566. PanK_bact. IPR006083. PRK/URK. [Graphical view]
KO	K00867.
PANTHER	PTHR10285:SF7. PanK_bact. 1 hit.
Pfam	PF00485. PRK. 1 hit. [Graphical view]
PIRSF	PIRSF000545. Pantothenate_kin. 1 hit.
TIGRFAMs	TIGR00554. PanK_bact. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B1W3X0_STRGG

Accession

Primary (citable) accession number: B1W3X0

Entry history

Integrated into UniProtKB/TrEMBL:	May 20, 2008
Last sequence update:	May 20, 2008
Last modified:	December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)