B1W3V9 (B1W3V9_STRGG) Unreviewed, UniProtKB/TrEMBL
Last modified
January 25, 2012.
Version 27.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Recommended name: Alanine racemase HAMAP MF_01201 RuleBase RU000608 EC=5.1.1.1 HAMAP MF_01201 RuleBase RU000608 | ||||
| Gene names |
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| Organism | Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 455632 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces |
Protein attributes
| Sequence length | 392 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Provides the D-alanine required for cell wall biosynthesis By similarity. HAMAP MF_01201 |
| Catalytic activity | L-alanine = D-alanine. HAMAP MF_01201 RuleBase RU000608 SAAS SAAS009006 |
| Cofactor | Pyridoxal phosphate By similarity. HAMAP MF_01201 RuleBase RU000608 SAAS SAAS009006 |
| Pathway | Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP MF_01201 RuleBase RU004247 SAAS SAAS009006 Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_01201 |
| Sequence similarities | Belongs to the alanine racemase family. HAMAP MF_01201 RuleBase RU004188 |
Ontologies
| Keywords | |
|---|---|
| Biological process | Cell shape Cell wall biogenesis/degradation HAMAP MF_01201 Peptidoglycan synthesis HAMAP MF_01201 |
| Ligand | Pyridoxal phosphate SAAS SAAS009006 HAMAP MF_01201 RuleBase RU000608 |
| Molecular function | Isomerase HAMAP MF_01201 RuleBase RU000608 SAAS SAAS009006 |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | alanine metabolic process Inferred from electronic annotation. Source: HAMAP cellular cell wall organizationInferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic processInferred from electronic annotation. Source: HAMAP regulation of cell shapeInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | alanine racemase activity Inferred from electronic annotation. Source: HAMAP pyridoxal phosphate bindingInferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Sites | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Active site | 39 | 1 | Proton acceptor; specific for D-alanine By similarity HAMAP MF_01201 | ||||||
| Active site | 271 | 1 | Proton acceptor; specific for L-alanine By similarity HAMAP MF_01201 | ||||||
Amino acid modifications | |||||||||
| Modified residue | 39 | 1 | N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01201 | ||||||
Sequences
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References
| [1] | "Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350." Ohnishi Y., Ishikawa J., Hara H., Suzuki H., Ikenoya M., Ikeda H., Yamashita A., Hattori M., Horinouchi S. J. Bacteriol. 190:4050-4060(2008) [PubMed: 18375553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AP009493 Genomic DNA. Translation: BAG19615.1. |
| RefSeq | YP_001824298.1. NC_010572.1. |
3D structure databases | |
| ProteinModelPortal | B1W3V9. |
| SMR | B1W3V9. Positions 8-379. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | B1W3V9. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 6210086. |
| GenomeReviews | Gene locus SGR_2786 in contig AP009493_GR. |
| KEGG | sgr:SGR_2786. |
| PATRIC | 23752103. VBIStrGri32265_2848. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | HBG712172. |
| OMA | EGTPVWV. |
| ProtClustDB | CLSK536972. |
Family and domain databases | |
| HAMAP | MF_01201. Ala_racemase. [Tree] |
| InterPro | IPR000821. Ala_racemase. IPR009006. Ala_racemase/Decarboxylase_C. IPR011079. Ala_racemase_C. IPR001608. Ala_racemase_N. IPR020622. Ala_racemase_pyridoxalP-BS. [Graphical view] |
| Gene3D | G3DSA:2.40.37.10. Ala_racemase/Decarboxylase_C. 1 hit. |
| KO | K01775. |
| Pfam | PF00842. Ala_racemase_C. 1 hit. PF01168. Ala_racemase_N. 1 hit. [Graphical view] |
| PRINTS | PR00992. ALARACEMASE. |
| SMART | SM01005. Ala_racemase_C. 1 hit. [Graphical view] |
| SUPFAM | SSF50621. Racem_decarbox_C. 1 hit. |
| TIGRFAMs | TIGR00492. Alr. 1 hit. |
| PROSITE | PS00395. ALANINE_RACEMASE. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | B1W3V9_STRGG | ||||||||
| Accession | Primary (citable) accession number: B1W3V9 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

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