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B1W3V9 (B1W3V9_STRGG) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alanine racemase HAMAP MF_01201 RuleBase RU000608
EC=5.1.1.1 HAMAP MF_01201 RuleBase RU000608
Gene names
Name:alr HAMAP MF_01201
Ordered Locus Names:SGR_2786
OrganismStreptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350) [Complete proteome] [HAMAP]
Taxonomic identifier455632 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length392 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the D-alanine required for cell wall biosynthesis By similarity. HAMAP MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP MF_01201 RuleBase RU000608 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP MF_01201 RuleBase RU000608 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP MF_01201 RuleBase RU004247 SAAS SAAS009006

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site391Proton acceptor; specific for D-alanine By similarity HAMAP MF_01201
Active site2711Proton acceptor; specific for L-alanine By similarity HAMAP MF_01201

Amino acid modifications

Modified residue391N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01201

Sequences

Sequence LengthMass (Da)Tools
B1W3V9 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: F561E3AA2B14A0AC

FASTA39240,603
        10         20         30         40         50         60 
MNETASLRAR AEIDLAALRA NVRVLRERAA GAQLMAVVKS DGYGHGAVPC ARAAREAGAT 

        70         80         90        100        110        120 
WLGTATPQEA LALRAAGLDG RIMCWLWTPG GPWREAIEAD IDVSVGGMWA LREVVAAAAA 

       130        140        150        160        170        180 
AGRTARIQLK ADTGLGRGGC QPADWPELVG EALAAERAGR VEVTGLWSHF ACADEPGHPS 

       190        200        210        220        230        240 
IAAQLAVYRD LVAYAEKEGV EPEVRHLANS PATLTIPEAH FDLVRTGIAM YGVSPAPELG 

       250        260        270        280        290        300 
TSADLGLRPV MTLAASVALV KDAPAGHGIS YGHHYTTTAE TTLGLIPVGY ADGVPRHASG 

       310        320        330        340        350        360 
TGPVLVGGKV RRVAGRVAMD QFVVDLDGDR PEAGAEAVLF GPGDRGEPTA QDWAEAAGTI 

       370        380        390 
AYEIVTRIGT RVPRVYVDGA AGPGEAAGGG RR

« Hide

References

[1]"Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350."
Ohnishi Y., Ishikawa J., Hara H., Suzuki H., Ikenoya M., Ikeda H., Yamashita A., Hattori M., Horinouchi S.
J. Bacteriol. 190:4050-4060(2008) [PubMed: 18375553] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP009493 Genomic DNA. Translation: BAG19615.1.
RefSeqYP_001824298.1. NC_010572.1.

3D structure databases

ProteinModelPortalB1W3V9.
SMRB1W3V9. Positions 8-379.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1W3V9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6210086.
GenomeReviewsGene locus SGR_2786 in contig AP009493_GR.
KEGGsgr:SGR_2786.
PATRIC23752103. VBIStrGri32265_2848.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG712172.
OMAEGTPVWV.
ProtClustDBCLSK536972.

Family and domain databases

HAMAPMF_01201. Ala_racemase.
[Tree]
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
Gene3DG3DSA:2.40.37.10. Ala_racemase/Decarboxylase_C. 1 hit.
KOK01775.
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMsTIGR00492. Alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB1W3V9_STRGG
AccessionPrimary (citable) accession number: B1W3V9
Entry history
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: January 25, 2012
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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