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B1W206 (B1W206_STRGG) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alanine dehydrogenase PIRNR PIRNR000183
EC=1.4.1.1 PIRNR PIRNR000183
Gene names
Ordered Locus Names:SGR_5724
OrganismStreptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350) [Complete proteome] [HAMAP]
Taxonomic identifier455632 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length371 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH. PIRNR PIRNR000183

Pathway

Amino-acid degradation; L-alanine degradation via dehydrogenase pathway; NH(3) and pyruvate from L-alanine: step 1/1. PIRNR PIRNR000183

Sequence similarities

Belongs to the AlaDH/PNT family. PIRNR PIRNR000183

Ontologies

Keywords
   LigandNAD PIRNR PIRNR000183
   Molecular functionOxidoreductase PIRNR PIRNR000183
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionalanine dehydrogenase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
B1W206 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: 38F36696C81059C0

FASTA37139,366
        10         20         30         40         50         60 
MKVGIPREVK NNEFRVAITP AGVHELVRHG HEVVIEHDAG VGSSIPDEEY VAAGARILAT 

        70         80         90        100        110        120 
ADEVWAAADL LLKVKEPVAE EYHRLRKDQT LFTYLHLAAS RECTDALLAS GTTAIAYETV 

       130        140        150        160        170        180 
ETANRALPLL APMSEVAGRL APQVGAYHLM RSVGGRGVLP GGVPGTAAGR AVVIGGGVSG 

       190        200        210        220        230        240 
WNATQIAVGL GFHVTLLDRD INKLREADRI FGTKVQTVVS NAFELEKAVV EADLVIGAVL 

       250        260        270        280        290        300 
IPGAKAPKLV TNELVAKMKP GSVLVDIAID QGGCFEDSRP TTHAEPTFQV HDSVFYCVAN 

       310        320        330        340        350        360 
MPGAVPHTST YALTNATLPY IVELANRGWA DALRRDAALA KGLNTHEGQV VYREVAEAHG 

       370 
LPHVELSALL G

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References

[1]"Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350."
Ohnishi Y., Ishikawa J., Hara H., Suzuki H., Ikenoya M., Ikeda H., Yamashita A., Hattori M., Horinouchi S.
J. Bacteriol. 190:4050-4060(2008) [PubMed: 18375553] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP009493 Genomic DNA. Translation: BAG22553.1.
RefSeqYP_001827236.1. NC_010572.1.

3D structure databases

ProteinModelPortalB1W206.
SMRB1W206. Positions 1-370.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1W206.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6214545.
GenomeReviewsGene locus SGR_5724 in contig AP009493_GR.
KEGGsgr:SGR_5724.
PATRIC23758247. VBIStrGri32265_5863.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG289735.
OMAVAHGHEV.
ProtClustDBCLSK2303389.

Family and domain databases

InterProIPR008142. Ala_DH/PNT_CS1.
IPR008141. Ala_DH/Pyr_transHydgase.
IPR007886. AlaDH/PNT_N.
IPR007698. AlaDH/PNT_NAD(H)-bd.
[Graphical view]
KOK00259.
PANTHERPTHR10160:SF3. PTHR10160:SF3. 1 hit.
PfamPF01262. AlaDh_PNT_C. 1 hit.
PF05222. AlaDh_PNT_N. 1 hit.
[Graphical view]
PIRSFPIRSF000183. Alanine_dh. 1 hit.
SMARTSM01002. AlaDh_PNT_C. 1 hit.
SM01003. AlaDh_PNT_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR00518. AlaDH. 1 hit.
PROSITEPS00836. ALADH_PNT_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB1W206_STRGG
AccessionPrimary (citable) accession number: B1W206
Entry history
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: January 25, 2012
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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