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B1W1A7 (B1W1A7_STRGG) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide deformylase 1 HAMAP MF_00163
Short name=PDF 1 HAMAP MF_00163
EC=3.5.1.88 HAMAP MF_00163
Alternative name(s):
Polypeptide deformylase 1 HAMAP MF_00163
Gene names
Name:def1 HAMAP MF_00163
Ordered Locus Names:SGR_2303
OrganismStreptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350) [Complete proteome] [HAMAP]
Taxonomic identifier455632 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length212 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions By similarity. HAMAP MF_00163

Catalytic activity

Formyl-L-methionyl peptide + H2O = formate + methionyl peptide. HAMAP MF_00163 SAAS SAAS000181

Cofactor

Binds 1 Fe2+ ion By similarity. HAMAP MF_00163

Sequence similarities

Belongs to the polypeptide deformylase family. HAMAP MF_00163 RuleBase RU003335

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1741 By similarity HAMAP MF_00163
Metal binding1311Iron By similarity HAMAP MF_00163
Metal binding1731Iron By similarity HAMAP MF_00163
Metal binding1771Iron By similarity HAMAP MF_00163

Sequences

Sequence LengthMass (Da)Tools
B1W1A7 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: 0866E762D012693A

FASTA21223,558
        10         20         30         40         50         60 
MSQQETDGRI GVDDEGFLVD TEDCEEREAA YRERGTSRPI TVVGNPVLHK ECKDVTEFDD 

        70         80         90        100        110        120 
ALARLIDDMF ASQRTAEGVG LAANQIGVDL KVFVYDCPDD DGVRHTGVIC NPVLEELAPE 

       130        140        150        160        170        180 
ARVLDDSNEG CLSVPTAYAS LARPDYAVVR GQDAQGNPVK VRGSGYFARC LQHETDHLYG 

       190        200        210 
YLYIDRLSKR ERKDALRQME EGTPRYEVVP NA

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References

[1]"Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350."
Ohnishi Y., Ishikawa J., Hara H., Suzuki H., Ikenoya M., Ikeda H., Yamashita A., Hattori M., Horinouchi S.
J. Bacteriol. 190:4050-4060(2008) [PubMed: 18375553] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP009493 Genomic DNA. Translation: BAG19132.1.
RefSeqYP_001823815.1. NC_010572.1.

3D structure databases

ProteinModelPortalB1W1A7.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1W1A7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6210554.
GenomeReviewsGene locus SGR_2303 in contig AP009493_GR.
KEGGsgr:SGR_2303.
PATRIC23751095. VBIStrGri32265_2346.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG665227.
OMATWMPGED.
ProtClustDBCLSK378634.

Family and domain databases

HAMAPMF_00163. Pep_deformylase.
[Tree]
InterProIPR000181. Fmet_deformylase.
IPR023635. Peptide_deformylase.
[Graphical view]
Gene3DG3DSA:3.90.45.10. Fmet_deformylase. 1 hit.
KOK01462.
PANTHERPTHR10458. Fmet_deformylase. 1 hit.
PfamPF01327. Pep_deformylase. 1 hit.
[Graphical view]
PIRSFPIRSF004749. Pep_def. 1 hit.
PRINTSPR01576. PDEFORMYLASE.
SUPFAMSSF56420. Fmet_deformylase. 1 hit.
TIGRFAMsTIGR00079. Pept_deformyl. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB1W1A7_STRGG
AccessionPrimary (citable) accession number: B1W1A7
Entry history
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: December 14, 2011
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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