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B1W0Z3 (PGK_STRGG) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein attributes

Sequence length403 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 403403Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_1000096379

Regions

Nucleotide binding359 – 3624ATP By similarity
Region22 – 243Substrate binding By similarity
Region60 – 634Substrate binding By similarity

Sites

Binding site371Substrate By similarity
Binding site1191Substrate By similarity
Binding site1561Substrate By similarity
Binding site2061ATP By similarity
Binding site3021ATP; via carbonyl oxygen By similarity
Binding site3331ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
B1W0Z3 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: 3CB588F596F55C77

FASTA40341,918
        10         20         30         40         50         60 
MKTIDELLAE GVAGKRVFVR ADLNVPLDGT TITDDGRIRA VVPTIAKLAE AGARVVVASH 

        70         80         90        100        110        120 
LGRPKGAPDP AFSLAPAATR LGELLGAEVA FAADTVGESA RAAVAGLADG RVAVVENLRF 

       130        140        150        160        170        180 
NAGETSKDDA ERGAFADQLA QLADVYVGDG FGAVHRKHAS VFDLPARLPH YAGYLIATEV 

       190        200        210        220        230        240 
GVLKKLTTDV HRPYAVVLGG AKVSDKLGVI DHLLERADRI LIGGGMAYTF LKAKGYEVGS 

       250        260        270        280        290        300 
SLLQEDQIPA VREYLRRAEE KGVEFVLPVD VVVAPSFPDL KTKAPAHPTT VAADAMPAGQ 

       310        320        330        340        350        360 
MGLDNGPETN KLYASKLADA ATVFWNGPMG VFEHPDFADG TRAVAQALVD SSAFSVVGGG 

       370        380        390        400 
DSAAAVRILG FDENAFGHIS TGGGASLEYL EGKTLPGLAA LED 

« Hide

References

[1]"Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350."
Ohnishi Y., Ishikawa J., Hara H., Suzuki H., Ikenoya M., Ikeda H., Yamashita A., Hattori M., Horinouchi S.
J. Bacteriol. 190:4050-4060(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JCM 4626 / NBRC 13350.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP009493 Genomic DNA. Translation: BAG22403.1.
RefSeqYP_001827086.1. NC_010572.1.

3D structure databases

ProteinModelPortalB1W0Z3.
SMRB1W0Z3. Positions 2-403.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING455632.SGR_5574.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAG22403; BAG22403; SGR_5574.
GeneID6209373.
KEGGsgr:SGR_5574.
PATRIC23757933. VBIStrGri32265_5709.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227107.
KOK00927.
OMAMSIRYID.
OrthoDBEOG64N9Z0.

Enzyme and pathway databases

BioCycSGRI455632:GD3A-5646-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_STRGG
AccessionPrimary (citable) accession number: B1W0Z3
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: May 20, 2008
Last modified: June 11, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways