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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei136GTPUniRule annotation1
Binding sitei140GTPUniRule annotation1
Binding sitei184GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi18 – 22GTPUniRule annotation5
Nucleotide bindingi105 – 107GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotationImported
Ordered Locus Names:SGR_5423Imported
OrganismiStreptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)Imported
Taxonomic identifieri455632 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces
Proteomesi
  • UP000001685 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi455632.SGR_5423

Structurei

3D structure databases

ProteinModelPortaliB1W0J2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 202TubulinInterPro annotationAdd BLAST193
Domaini204 – 321Tubulin_CInterPro annotationAdd BLAST118

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDK Bacteria
COG0206 LUCA
HOGENOMiHOG000049094
KOiK03531
OMAiMRAVKGI

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.30.1330.20, 1 hit
3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

B1W0J2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAPQNYLAV IKVIGVGGGG VNAINRMIEV GLKGVEFIAI NTDAQALLMS
60 70 80 90 100
DADVKLDVGR ELTRGLGAGA NPAVGRKAAE DHREEIEEVL KGADMVFVTA
110 120 130 140 150
GEGGGTGTGG APVVANIARS LGALTIGVVT RPFTFEGRRR ANQAEDGIAE
160 170 180 190 200
LREEVDTLIV IPNDRLLSIS DRQVSVLDAF KSADQVLLSG VQGITDLITT
210 220 230 240 250
PGLINLDFAD VKSVMSEAGS ALMGIGSARG DDRAVAAAEM AISSPLLEAS
260 270 280 290 300
IDGARGVLLS ISGGSDLGLF EINEAAQLVS EAAHPEANII FGAVIDDALG
310 320 330 340 350
DEVRVTVIAA GFDGGQPPAR RENVLGANSN KREEPAAPAR SSAESTRPTG
360 370 380 390 400
GLGSVPPREE SPAPAEPAPA TASGESSLGP VSPPHVPPAR PYQDTQAEEL

DVPDFLK
Length:407
Mass (Da):41,711
Last modified:May 20, 2008 - v1
Checksum:i0E739C8E052C90C5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009493 Genomic DNA Translation: BAG22252.1
RefSeqiWP_003969707.1, NC_010572.1

Genome annotation databases

EnsemblBacteriaiBAG22252; BAG22252; SGR_5423
GeneIDi6215269
KEGGisgr:SGR_5423
PATRICifig|455632.4.peg.5554

Similar proteinsi

Entry informationi

Entry nameiB1W0J2_STRGG
AccessioniPrimary (citable) accession number: B1W0J2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: March 28, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health