B1W0G6 (B1W0G6_STRGG) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative 2-oxoglutarate dehydrogenase EMBL BAG19055.1

Gene names

Ordered Locus Names:

SGR_2226

Organism

Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350) [Complete proteome] [HAMAP]

Taxonomic identifier

455632 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length	1267 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the 2-oxoacid dehydrogenase family. RuleBase RU003423

Ontologies

Keywords
Ligand	Thiamine pyrophosphate SAAS SAAS001017
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular function	oxoglutarate dehydrogenase (succinyl-transferring) activity Inferred from electronic annotation. Source: InterPro thiamine pyrophosphate binding Inferred from electronic annotation. Source: InterPro transferase activity, transferring acyl groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1W0G6 [UniParc]. Last modified May 20, 2008. Version 1. Checksum: 3B772F9E42B01161	FASTA	1,267	138,520
	10 20 30 40 50 60 MSSQSPSNSS ISTDQAGPGT NPAAAFGANE WLVDEIYQQY LQDPSSVDRA WWDFFADYKP 70 80 90 100 110 120 GASGTADKPV PGVAPVTGAP AAPAASAPAA APAPAKAAPA AAPAAPAQPA PAKAAPAAPA 130 140 150 160 170 180 KPAAAKPAAA PAKAKPKADE STEAPAGPEY VTLRGPSAAV AKNMNASLEL PTATSVRAVP 190 200 210 220 230 240 VKLLFDNRIV INNHLKRARG GKISFTHLIG YAMVQALKAM PSMNYSFAEK DGKPTLVKPE 250 260 270 280 290 300 HVNLGLAIDL VKPNGDRQLV VAAIKKAETL NFFEFWQAYE DIVRRARIGK LGMDDFTGVT 310 320 330 340 350 360 ASLTNPGGIG TVHSVPRLMP GQGLIMGVGA MDYPAEFQGT SQDTLNKLGI SKVMTLTSTY 370 380 390 400 410 420 DHRVIQGAAS GEFLRVLSQL LLGENEFYDE IFKALRIPYE PVRWLKDIDA SHDDDVTKAA 430 440 450 460 470 480 RVFELIHSYR VRGHVMADTD PLEYHQRKHP DLDITEHGLT LWDLERDFAV GGFAGKTMMK 490 500 510 520 530 540 LRDILGVLRE SYCRTTGIEF MHIQDPSQRK WLQDRVERAR PKPEREEQLR ILRRLNAAEA 550 560 570 580 590 600 FETFLQTKYV GQKRFSLEGG ESVIPLLDAV IDSAAEARLD EVVIGMAHRG RLNVLANIVG 610 620 630 640 650 660 KSYAQIFREF EGNLDPRSMH GSGDVKYHLG AEGTFTGLDG EQIKVSLAAN PSHLEAVDPV 670 680 690 700 710 720 LEGIARAKQD IINKGGTDFT VLPVALHGDA AFAGQGVVAE TLNMSQLRGY RTGGTVHVVI 730 740 750 760 770 780 NNQVGFTAAP ESSRSSMYAT DVARMIEAPI IHVNGDDPEA VVRVARLAFE FRQAFNKDVV 790 800 810 820 830 840 IDLICYRRRG HNETDNPEFT NPQMYTLVDK KRSVRKLYTE SLIGRGDITL EEAEQALQDF 850 860 870 880 890 900 QGQLEKVFAE VREATSQPAA PHVPEPQAAF PVAVETAVSA EVVKRIAESQ VNIPESITVH 910 920 930 940 950 960 PRLMPQMQRR AASVDNATID WGMGETLAIG SLLMEGTPVR LAGQDTRRGT FGQRHAVLVD 970 980 990 1000 1010 1020 QVTGEDYTPL LYLADDQARY NVYDSLLSEY AAMGFEYGYS LARPESLVIW EAQFGDFVNG 1030 1040 1050 1060 1070 1080 AQTVVDEFIS SAEQKWGQTS GVTLLLPHGY EGQGPDHSSA RPERFLQMCA QDNMTVAMPT 1090 1100 1110 1120 1130 1140 LPSNYFHLLR WQVHNPHHKP LIVFTPKSML RLKAAASSIE EFTTGGFRPV IGDTSVKPEN 1150 1160 1170 1180 1190 1200 VRKVVFCAGK LFYDLDAERE KRGDTETAII RLERLYPLPG AEIQAEIAKY PNAEKYLWAQ 1210 1220 1230 1240 1250 1260 EEPANQGAWP FIALNLIDHL DLAVGSDVPH GERLRRISRP HGSSPAVGSA KRHQAEQTQL VNEVFEA

References

[1]

"Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350." Ohnishi Y., Ishikawa J., Hara H., Suzuki H., Ikenoya M., Ikeda H., Yamashita A., Hattori M., Horinouchi S. J. Bacteriol. 190:4050-4060(2008) [PubMed: 18375553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009493 Genomic DNA. Translation: BAG19055.1.
RefSeq	YP_001823738.1. NC_010572.1.
3D structure databases
ProteinModelPortal	B1W0G6.
ModBase	Search...
Protein-protein interaction databases
STRING	B1W0G6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6209457.
GenomeReviews	Gene locus SGR_2226 in contig AP009493_GR.
KEGG	sgr:SGR_2226.
PATRIC	23750935. VBIStrGri32265_2266.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG289950.
OMA	EGDEPAF.
ProtClustDB	PRK12270.
Family and domain databases
InterPro	IPR001078. 2-oxoacid_DH_actylTfrase. IPR011603. 2oxoglutarate_DH_E1. IPR023213. CAT-like_dom. IPR001017. DH_E1. IPR005475. Transketolase-like_Pyr-bd. [Graphical view]
Gene3D	G3DSA:3.30.559.10. CAT-like_dom. 1 hit.
KO	K00164.
PANTHER	PTHR23152. 2oxoglutarate_DH_E1. 1 hit.
Pfam	PF00198. 2-oxoacid_dh. 1 hit. PF00676. E1_dh. 1 hit. PF02779. Transket_pyr. 1 hit. [Graphical view]
PIRSF	PIRSF000157. Oxoglu_dh_E1. 1 hit.
SMART	SM00861. Transket_pyr. 1 hit. [Graphical view]
TIGRFAMs	TIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B1W0G6_STRGG

Accession

Primary (citable) accession number: B1W0G6

Entry history

Integrated into UniProtKB/TrEMBL:	May 20, 2008
Last sequence update:	May 20, 2008
Last modified:	December 14, 2011
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)