B1VZY5 (B1VZY5_STRGG) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aminomethyltransferase HAMAP MF_00259 RuleBase RU003981
EC=2.1.2.10 HAMAP MF_00259 RuleBase RU003981

Alternative name(s):
Glycine cleavage system T protein HAMAP MF_00259

Gene names

Name:	gcvT HAMAP MF_00259
Ordered Locus Names:	SGR_2045

Organism

Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350) [Complete proteome] [HAMAP]

Taxonomic identifier

455632 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length	371 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The glycine cleavage system catalyzes the degradation of glycine By similarity. HAMAP MF_00259 RuleBase RU003981 SAAS SAAS022903
Catalytic activity	[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. HAMAP MF_00259 RuleBase RU003981 SAAS SAAS022903
Subunit structure	The glycine cleavage system is composed of four proteins: P, T, L and H By similarity. HAMAP MF_00259 RuleBase RU003981 SAAS SAAS022903
Sequence similarities	Belongs to the GcvT family. HAMAP MF_00259 RuleBase RU003980

Ontologies

Keywords
Molecular function	Aminotransferase HAMAP MF_00259 RuleBase RU003981 SAAS SAAS022903 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine decarboxylation via glycine cleavage system Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	aminomethyltransferase activity Inferred from electronic annotation. Source: HAMAP transaminase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1VZY5 [UniParc]. Last modified May 20, 2008. Version 1. Checksum: 0620CD1DAE243B00	FASTA	371	39,334
	10 20 30 40 50 60 MSTAPRLTAL DTLHRSLGAT MTDFAGWDMP LRYASERDEH NAVRTRAGLF DLSHMGEITV 70 80 90 100 110 120 TGPEAAAFLS YALVGNIATV GNGRARYTMI VREDGGIVDD LIVYRLGESE YMVVANAGNA 130 140 150 160 170 180 QIVLDALTER VSGFDAEVRD DRDAYALLAV QGPESPAIMK AVTDADLDGL KYYAGLPGTV 190 200 210 220 230 240 AGVPALIART GYTGEDGFEL FVAPEHAEQL WRALTEAGAP HGLIPCGLSC RDTLRLEAGM 250 260 270 280 290 300 PLYGHELTTA LTPFDAGLGR VVKFEKEGDF VGRAALTAAA ERAETAPPRK LVGLIAEGRR 310 320 330 340 350 360 VPRAGFAVVA DGKVIGEVTS GAPSPTLGRP IAMAYVDAAF AAPGTEGVGV DIRGTHEPYE 370 VVALPFYKRQ K

References

[1]

"Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350." Ohnishi Y., Ishikawa J., Hara H., Suzuki H., Ikenoya M., Ikeda H., Yamashita A., Hattori M., Horinouchi S. J. Bacteriol. 190:4050-4060(2008) [PubMed: 18375553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009493 Genomic DNA. Translation: BAG18874.1.
RefSeq	YP_001823557.1. NC_010572.1.
3D structure databases
ProteinModelPortal	B1VZY5.
ModBase	Search...
Protein-protein interaction databases
STRING	B1VZY5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6213303.
GenomeReviews	Gene locus SGR_2045 in contig AP009493_GR.
KEGG	sgr:SGR_2045.
PATRIC	23750553. VBIStrGri32265_2076.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG299834.
OMA	KALYGGM.
ProtClustDB	PRK00389.
Family and domain databases
HAMAP	MF_00259. GcvT. [Tree]
InterPro	IPR013977. GCV_T_C. IPR006222. GCV_T_N. IPR006223. GcvT. IPR022903. NH2_Me_Trfase. [Graphical view]
KO	K00605.
PANTHER	PTHR13847:SF5. PTHR13847:SF5. 1 hit.
Pfam	PF01571. GCV_T. 1 hit. PF08669. GCV_T_C. 1 hit. [Graphical view]
PIRSF	PIRSF006487. GcvT. 1 hit.
TIGRFAMs	TIGR00528. GcvT. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B1VZY5_STRGG

Accession

Primary (citable) accession number: B1VZY5

Entry history

Integrated into UniProtKB/TrEMBL:	May 20, 2008
Last sequence update:	May 20, 2008
Last modified:	December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)