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Protein

Elongation factor Ts

Gene

tsf

Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Elongation factor

Keywords - Biological processi

Protein biosynthesis

Enzyme and pathway databases

BioCyciSGRI455632:GD3A-1870-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TsUniRule annotation
Short name:
EF-TsUniRule annotation
Gene namesi
Name:tsfUniRule annotation
Ordered Locus Names:SGR_1862
OrganismiStreptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
Taxonomic identifieri455632 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces
Proteomesi
  • UP000001685 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 278278Elongation factor TsPRO_1000189888Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi455632.SGR_1862.

Structurei

3D structure databases

ProteinModelPortaliB1VYT6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni82 – 854Involved in Mg(2+) ion dislocation from EF-TuUniRule annotation

Sequence similaritiesi

Belongs to the EF-Ts family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CU7. Bacteria.
COG0264. LUCA.
HOGENOMiHOG000220986.
KOiK02357.
OMAiFIMEPKK.
OrthoDBiEOG66B42N.

Family and domain databases

Gene3Di3.30.479.20. 3 hits.
HAMAPiMF_00050. EF_Ts.
InterProiIPR001816. Transl_elong_EFTs/EF1B.
IPR014039. Transl_elong_EFTs/EF1B_dimer.
IPR018101. Transl_elong_Ts_CS.
IPR009060. UBA-like.
[Graphical view]
PANTHERiPTHR11741. PTHR11741. 1 hit.
PfamiPF00889. EF_TS. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
SSF54713. SSF54713. 2 hits.
TIGRFAMsiTIGR00116. tsf. 1 hit.
PROSITEiPS01126. EF_TS_1. 1 hit.
PS01127. EF_TS_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1VYT6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANYTAADVK KLRELTGAGM MDCKKALDEA DGNVDKAVEA LRIKGQKGVA
60 70 80 90 100
KREGRSAENG AVVSLISEDQ TSGVLLELKC ETDFVAKGDK FQAVANTLAA
110 120 130 140 150
HVAATSPADI EALLASEIEA GKTVQAYVDE ANANLGEKIV LDRFAQFTGA
160 170 180 190 200
YVGVYMHRTM PDLPPQIGVL VELDKADAEL AKGIAQHIAA FAPKYLSRED
210 220 230 240 250
VPAEVVEAER RVAEETTRAE GKPEAALPKI VEGRVNGFFK EATLLGQPYA
260 270
LDAKKSVQKV LDEAGVTLKR FSRIKVGI
Length:278
Mass (Da):29,755
Last modified:May 20, 2008 - v1
Checksum:i7F0197C3EFA12A35
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009493 Genomic DNA. Translation: BAG18691.1.
RefSeqiWP_003965939.1. NC_010572.1.

Genome annotation databases

EnsemblBacteriaiBAG18691; BAG18691; SGR_1862.
GeneIDi6215056.
KEGGisgr:SGR_1862.
PATRICi23750181. VBIStrGri32265_1895.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009493 Genomic DNA. Translation: BAG18691.1.
RefSeqiWP_003965939.1. NC_010572.1.

3D structure databases

ProteinModelPortaliB1VYT6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi455632.SGR_1862.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAG18691; BAG18691; SGR_1862.
GeneIDi6215056.
KEGGisgr:SGR_1862.
PATRICi23750181. VBIStrGri32265_1895.

Phylogenomic databases

eggNOGiENOG4105CU7. Bacteria.
COG0264. LUCA.
HOGENOMiHOG000220986.
KOiK02357.
OMAiFIMEPKK.
OrthoDBiEOG66B42N.

Enzyme and pathway databases

BioCyciSGRI455632:GD3A-1870-MONOMER.

Family and domain databases

Gene3Di3.30.479.20. 3 hits.
HAMAPiMF_00050. EF_Ts.
InterProiIPR001816. Transl_elong_EFTs/EF1B.
IPR014039. Transl_elong_EFTs/EF1B_dimer.
IPR018101. Transl_elong_Ts_CS.
IPR009060. UBA-like.
[Graphical view]
PANTHERiPTHR11741. PTHR11741. 1 hit.
PfamiPF00889. EF_TS. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
SSF54713. SSF54713. 2 hits.
TIGRFAMsiTIGR00116. tsf. 1 hit.
PROSITEiPS01126. EF_TS_1. 1 hit.
PS01127. EF_TS_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350."
    Ohnishi Y., Ishikawa J., Hara H., Suzuki H., Ikenoya M., Ikeda H., Yamashita A., Hattori M., Horinouchi S.
    J. Bacteriol. 190:4050-4060(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JCM 4626 / NBRC 13350.

Entry informationi

Entry nameiEFTS_STRGG
AccessioniPrimary (citable) accession number: B1VYT6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: May 20, 2008
Last modified: December 9, 2015
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.