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Protein

Protein RecA

Gene

recA

Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.UniRule annotationSAAS annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi66 – 738ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotationSAAS annotation, DNA repair, SOS responseUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, DNA-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciSGRI455632:GD3A-1749-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein RecAUniRule annotationSAAS annotation
Alternative name(s):
Recombinase AUniRule annotation
Gene namesi
Name:recAUniRule annotationImported
Ordered Locus Names:SGR_1745Imported
OrganismiStreptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)Imported
Taxonomic identifieri455632 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces
Proteomesi
  • UP000001685 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi455632.SGR_1745.

Structurei

3D structure databases

ProteinModelPortaliB1VXV8.
SMRiB1VXV8. Positions 5-330.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini36 – 195160RECA_2InterPro annotationAdd
BLAST
Domaini200 – 27374RECA_3InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the RecA family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105C68. Bacteria.
COG0468. LUCA.
HOGENOMiHOG000264120.
KOiK03553.
OMAiTRKGAWY.
OrthoDBiEOG6ZKXNZ.

Family and domain databases

Gene3Di3.30.250.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00268. RecA.
InterProiIPR003593. AAA+_ATPase.
IPR013765. DNA_recomb/repair_RecA.
IPR020584. DNA_recomb/repair_RecA_CS.
IPR027417. P-loop_NTPase.
IPR020588. RecA_ATP-bd.
IPR023400. RecA_C.
IPR020587. RecA_monomer-monomer_interface.
[Graphical view]
PANTHERiPTHR22942:SF1. PTHR22942:SF1. 1 hit.
PfamiPF00154. RecA. 1 hit.
[Graphical view]
PRINTSiPR00142. RECA.
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF54752. SSF54752. 1 hit.
TIGRFAMsiTIGR02012. tigrfam_recA. 1 hit.
PROSITEiPS00321. RECA_1. 1 hit.
PS50162. RECA_2. 1 hit.
PS50163. RECA_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1VXV8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGNDREKAL DAALAQIERQ FGKGAVMRLG ERPNEPIEVI PTGSTALDVA
60 70 80 90 100
LGVGGLPRGR VVEVYGPESS GKTTLTLHAV ANAQKLGGSV AFIDAEHALD
110 120 130 140 150
PEYAKKLGVD IDSLILSQPD NGEQALEIVD MLVRSGALDL IVIDSVAALV
160 170 180 190 200
PRAEIEGEMG DSHVGLQARL MSQALRKITS ALNQSKTTAI FINQLREKIG
210 220 230 240 250
VMFGSPETTT GGRALKFYAS VRLDIRRIET LKDGTDAVGN RTRVKVVKNK
260 270 280 290 300
VAPPFKQAEF DILYGQGISR EGGLIDMGVE HGFVRKAGAW YTYEGDQLGQ
310 320 330 340 350
GKENARNFLK DNPDLANEIE KKILEKLGVG VRPDADAGEP AADAAAAAAP
360 370
AADGAAKPAA TSAAKAKPAK TAAAKS
Length:376
Mass (Da):39,584
Last modified:May 20, 2008 - v1
Checksum:iF0C93A25F4EB9CBA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009493 Genomic DNA. Translation: BAG18574.1.
RefSeqiWP_012378752.1. NC_010572.1.

Genome annotation databases

EnsemblBacteriaiBAG18574; BAG18574; SGR_1745.
GeneIDi6215868.
KEGGisgr:SGR_1745.
PATRICi23749927. VBIStrGri32265_1772.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009493 Genomic DNA. Translation: BAG18574.1.
RefSeqiWP_012378752.1. NC_010572.1.

3D structure databases

ProteinModelPortaliB1VXV8.
SMRiB1VXV8. Positions 5-330.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi455632.SGR_1745.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAG18574; BAG18574; SGR_1745.
GeneIDi6215868.
KEGGisgr:SGR_1745.
PATRICi23749927. VBIStrGri32265_1772.

Phylogenomic databases

eggNOGiENOG4105C68. Bacteria.
COG0468. LUCA.
HOGENOMiHOG000264120.
KOiK03553.
OMAiTRKGAWY.
OrthoDBiEOG6ZKXNZ.

Enzyme and pathway databases

BioCyciSGRI455632:GD3A-1749-MONOMER.

Family and domain databases

Gene3Di3.30.250.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00268. RecA.
InterProiIPR003593. AAA+_ATPase.
IPR013765. DNA_recomb/repair_RecA.
IPR020584. DNA_recomb/repair_RecA_CS.
IPR027417. P-loop_NTPase.
IPR020588. RecA_ATP-bd.
IPR023400. RecA_C.
IPR020587. RecA_monomer-monomer_interface.
[Graphical view]
PANTHERiPTHR22942:SF1. PTHR22942:SF1. 1 hit.
PfamiPF00154. RecA. 1 hit.
[Graphical view]
PRINTSiPR00142. RECA.
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF54752. SSF54752. 1 hit.
TIGRFAMsiTIGR02012. tigrfam_recA. 1 hit.
PROSITEiPS00321. RECA_1. 1 hit.
PS50162. RECA_2. 1 hit.
PS50163. RECA_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350."
    Ohnishi Y., Ishikawa J., Hara H., Suzuki H., Ikenoya M., Ikeda H., Yamashita A., Hattori M., Horinouchi S.
    J. Bacteriol. 190:4050-4060(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JCM 4626 / NBRC 13350Imported.

Entry informationi

Entry nameiB1VXV8_STRGG
AccessioniPrimary (citable) accession number: B1VXV8
Entry historyi
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: May 11, 2016
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.