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B1VV20 (PSD_STRGG) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:SGR_1175
OrganismStreptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350) [Complete proteome] [HAMAP]
Taxonomic identifier455632 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length215 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00664

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00664

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00664

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 3 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphosphatidylethanolamine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular functioncofactor binding

Inferred from electronic annotation. Source: InterPro

phosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 184184Phosphatidylserine decarboxylase beta chain By similarity
PRO_1000131492
Chain185 – 21531Phosphatidylserine decarboxylase alpha chain By similarity
PRO_1000131493

Sites

Site184 – 1852Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue1851Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
B1VV20 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: 950323F3D844C805

FASTA21523,183
        10         20         30         40         50         60 
MPDSTSSASR GGVRIARGAS PWLLPTVATA ALSLARARKS GRWAAVAVPT TALAAGMLWF 

        70         80         90        100        110        120 
FRDPEREITD GRVISPADGV VQSIMPWKDG RTRVAIFMSP LNVHVNRAPL AGTVTSVEHI 

       130        140        150        160        170        180 
PGGFVPAFNK ESENNERVVW HFDTELGDIE MVQIAGAVAR RIVPYLPEGT KVEQGERIGL 

       190        200        210 
IRFGSRVDIY LPEGIDVAVE VGQATTAGVT RIDRD

« Hide

References

[1]"Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350."
Ohnishi Y., Ishikawa J., Hara H., Suzuki H., Ikenoya M., Ikeda H., Yamashita A., Hattori M., Horinouchi S.
J. Bacteriol. 190:4050-4060(2008) [PubMed: 18375553] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JCM 4626 / NBRC 13350.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP009493 Genomic DNA. Translation: BAG18004.1.
RefSeqYP_001822687.1. NC_010572.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB1VV20.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6212305.
GenomeReviewsGene locus SGR_1175 in contig AP009493_GR.
KEGGsgr:SGR_1175.
PATRIC23748733. VBIStrGri32265_1175.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG541103.
OMANERVVWH.
ProtClustDBPRK05305.

Family and domain databases

HAMAPMF_00664. PS_decarb_type3.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR004428. PtdSer_deCO2ase-related.
[Graphical view]
KOK01613.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00164. PS_decarb_rel. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_STRGG
AccessionPrimary (citable) accession number: B1VV20
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: May 20, 2008
Last modified: January 25, 2012
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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