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B1VTB7 (SYR_STRGG) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:SGR_4178
OrganismStreptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350) [Complete proteome] [HAMAP]
Taxonomic identifier455632 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

Protein attributes

Sequence length594 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 594594Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000095408

Regions

Motif127 – 13711"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
B1VTB7 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: D572DB562773B6BA

FASTA59464,757
        10         20         30         40         50         60 
MASVPSLAST LQQQLADALT AALPDAGAAD PLLRRSDRAD FQANGILALA KKLKGNPREL 

        70         80         90        100        110        120 
AAQVTAALPA GGLIKDIEVS GPGFLNVTLT DRAIVETLAA RAADGEGRLG VPLKDDAGTT 

       130        140        150        160        170        180 
VIDYAQPNVA KEMHVGHLRS AVIGDAVVRI LEFTGENVVR RHHIGDWGTQ FGMLIQYLIE 

       190        200        210        220        230        240 
HPGALQHEGG PGDGASDGEA AMSTLNRVYK ESRALFDSDE EFKARSRDRV VALQAGDPGT 

       250        260        270        280        290        300 
LELWHRFVDE SKIYFHSVFD KLDMEIRDPD IVGESGYNDM LEETCRILEE TGVAVRSEGA 

       310        320        330        340        350        360 
LCVFFDDVKG PDGNRVPLIV KKTNGGYGYA ATDLSAVRNR VQDLKADTLL YVVDARQSLH 

       370        380        390        400        410        420 
FRMVFETARR AGWLGDDVKA VQLAFGTVLG KDGKPFKTRE GETVRLEDLL DEAVQRATAV 

       430        440        450        460        470        480 
VRDKAEKVGL SEEEIVENGR YVGIGAVKYA DLSTSAVRDY KFDLDQMVAL HGDTSVYLQY 

       490        500        510        520        530        540 
AYARIRSILR KAGDAVPAAH PELELAPAER ALGLHLDQFG EVLAEVGTGY EPHKLAAYLY 

       550        560        570        580        590 
QLASHLTTFY DQCQVLSPDN APEVVENRLF LVELTARTLH RGMALLGIRT PERL 

« Hide

References

[1]"Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350."
Ohnishi Y., Ishikawa J., Hara H., Suzuki H., Ikenoya M., Ikeda H., Yamashita A., Hattori M., Horinouchi S.
J. Bacteriol. 190:4050-4060(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JCM 4626 / NBRC 13350.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP009493 Genomic DNA. Translation: BAG21007.1.
RefSeqYP_001825690.1. NC_010572.1.

3D structure databases

ProteinModelPortalB1VTB7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING455632.SGR_4178.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAG21007; BAG21007; SGR_4178.
GeneID6209259.
KEGGsgr:SGR_4178.
PATRIC23754978. VBIStrGri32265_4255.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247212.
KOK01887.
OMAPHIIFEN.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycSGRI455632:GD3A-4226-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_STRGG
AccessionPrimary (citable) accession number: B1VTB7
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: May 20, 2008
Last modified: May 14, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries