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B1VS80

- GPMA_STRGG

UniProt

B1VS80 - GPMA_STRGG

Protein

2,3-bisphosphoglycerate-dependent phosphoglycerate mutase

Gene

gpmA

Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 42 (01 Oct 2014)
      Sequence version 1 (20 May 2008)
      Previous versions | rss
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    • Comment

    Functioni

    Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.UniRule annotation

    Catalytic activityi

    2-phospho-D-glycerate = 3-phospho-D-glycerate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei13 – 131Tele-phosphohistidine intermediateUniRule annotation
    Binding sitei19 – 1912-phospho-D-glycerateUniRule annotation
    Binding sitei64 – 6412-phospho-D-glycerateUniRule annotation
    Binding sitei102 – 10212-phospho-D-glycerateUniRule annotation
    Active sitei186 – 1861UniRule annotation
    Binding sitei188 – 18812-phospho-D-glycerateUniRule annotation

    GO - Molecular functioni

    1. 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Glycolysis

    Enzyme and pathway databases

    BioCyciSGRI455632:GD3A-4049-MONOMER.
    UniPathwayiUPA00109; UER00186.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    2,3-bisphosphoglycerate-dependent phosphoglycerate mutaseUniRule annotation (EC:5.4.2.11UniRule annotation)
    Short name:
    BPG-dependent PGAMUniRule annotation
    Short name:
    PGAMUniRule annotation
    Short name:
    PhosphoglyceromutaseUniRule annotation
    Short name:
    dPGMUniRule annotation
    Gene namesi
    Name:gpmAUniRule annotation
    Ordered Locus Names:SGR_4005
    OrganismiStreptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
    Taxonomic identifieri455632 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces
    ProteomesiUP000001685: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 2532532,3-bisphosphoglycerate-dependent phosphoglycerate mutasePRO_1000135980Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi455632.SGR_4005.

    Structurei

    3D structure databases

    ProteinModelPortaliB1VS80.
    SMRiB1VS80. Positions 8-242.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni25 – 2622-phospho-D-glycerate bindingUniRule annotation
    Regioni91 – 9442-phospho-D-glycerate bindingUniRule annotation
    Regioni118 – 11922-phospho-D-glycerate bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0588.
    HOGENOMiHOG000221682.
    KOiK01834.
    OMAiWTILEGT.
    OrthoDBiEOG6C8N1H.

    Family and domain databases

    Gene3Di3.40.50.1240. 1 hit.
    HAMAPiMF_01039. PGAM_GpmA.
    InterProiIPR013078. His_Pase_superF_clade-1.
    IPR029033. His_PPase_superfam.
    IPR001345. PG/BPGM_mutase_AS.
    IPR005952. Phosphogly_mut1.
    [Graphical view]
    PANTHERiPTHR11931. PTHR11931. 1 hit.
    PfamiPF00300. His_Phos_1. 1 hit.
    [Graphical view]
    SMARTiSM00855. PGAM. 1 hit.
    [Graphical view]
    SUPFAMiSSF53254. SSF53254. 1 hit.
    TIGRFAMsiTIGR01258. pgm_1. 1 hit.
    PROSITEiPS00175. PG_MUTASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B1VS80-1 [UniParc]FASTAAdd to Basket

    « Hide

    MADAPYKLIL LRHGESEWNA KNLFTGWVDV NLTEKGEKEA VRGGELLKDA    50
    GLLPDVLHTS LQRRAIRTAQ LALESADRLW IPVRRSWRLN ERHYGALQGK 100
    DKAQTLAEFG EEQFMLWRRS YDTPPPPLAR DDEFSQFDDP RYATLPPEVR 150
    PDTECLKDVV VRMLPYWFDS IVPDLLTGRT VLVAAHGNSL RGLVKHLDGI 200
    SDEDISGLNI PTGIPLSYEL DADFKPLKPG GTYLDPDAAK AAIEAVKNQG 250
    KKK 253
    Length:253
    Mass (Da):28,425
    Last modified:May 20, 2008 - v1
    Checksum:i805B19AE803FD97C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP009493 Genomic DNA. Translation: BAG20834.1.
    RefSeqiYP_001825517.1. NC_010572.1.

    Genome annotation databases

    EnsemblBacteriaiBAG20834; BAG20834; SGR_4005.
    GeneIDi6214098.
    KEGGisgr:SGR_4005.
    PATRICi23754614. VBIStrGri32265_4077.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP009493 Genomic DNA. Translation: BAG20834.1 .
    RefSeqi YP_001825517.1. NC_010572.1.

    3D structure databases

    ProteinModelPortali B1VS80.
    SMRi B1VS80. Positions 8-242.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 455632.SGR_4005.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAG20834 ; BAG20834 ; SGR_4005 .
    GeneIDi 6214098.
    KEGGi sgr:SGR_4005.
    PATRICi 23754614. VBIStrGri32265_4077.

    Phylogenomic databases

    eggNOGi COG0588.
    HOGENOMi HOG000221682.
    KOi K01834.
    OMAi WTILEGT.
    OrthoDBi EOG6C8N1H.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00186 .
    BioCyci SGRI455632:GD3A-4049-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.1240. 1 hit.
    HAMAPi MF_01039. PGAM_GpmA.
    InterProi IPR013078. His_Pase_superF_clade-1.
    IPR029033. His_PPase_superfam.
    IPR001345. PG/BPGM_mutase_AS.
    IPR005952. Phosphogly_mut1.
    [Graphical view ]
    PANTHERi PTHR11931. PTHR11931. 1 hit.
    Pfami PF00300. His_Phos_1. 1 hit.
    [Graphical view ]
    SMARTi SM00855. PGAM. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53254. SSF53254. 1 hit.
    TIGRFAMsi TIGR01258. pgm_1. 1 hit.
    PROSITEi PS00175. PG_MUTASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350."
      Ohnishi Y., Ishikawa J., Hara H., Suzuki H., Ikenoya M., Ikeda H., Yamashita A., Hattori M., Horinouchi S.
      J. Bacteriol. 190:4050-4060(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: JCM 4626 / NBRC 13350.

    Entry informationi

    Entry nameiGPMA_STRGG
    AccessioniPrimary (citable) accession number: B1VS80
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: May 20, 2008
    Last modified: October 1, 2014
    This is version 42 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3