B1VR56 (B1VR56_STRGG) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligase RuleBase RU004370
EC=6.3.3.1 RuleBase RU004370

Gene names

Ordered Locus Names:

SGR_3878

Organism

Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350) [Complete proteome] [HAMAP]

Taxonomic identifier

455632 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length	357 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole. RuleBase RU004370 SAAS SAAS004733
Pathway	Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2. RuleBase RU004371 SAAS SAAS004733
Subcellular location	Cytoplasm By similarity SAAS SAAS004733.
Sequence similarities	Belongs to the AIR synthase family. RuleBase RU004370

Ontologies

Keywords
Biological process	Purine biosynthesis SAAS SAAS004733
Cellular component	Cytoplasm SAAS SAAS004733
Ligand	ATP-binding SAAS SAAS004733 Nucleotide-binding
Molecular function	Ligase RuleBase RU004370 SAAS SAAS004733
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	'de novo' IMP biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoribosylformylglycinamidine cyclo-ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1VR56 [UniParc]. Last modified May 20, 2008. Version 1. Checksum: D92FD93116FA8C07	FASTA	357	37,430
	10 20 30 40 50 60 MSETTGASYA AAGVDIEAGD RAVELMKEWV KKTQRPEVAG LGGLGGFAGL FDASALKRYE 70 80 90 100 110 120 RPLLASATDG VGTKVDLARR MGVYDTIGHD LVGMVVDDLV VCGAEPLFMT DYICVGKVHP 130 140 150 160 170 180 ERVAAIVKGI AEGCVLAGCS LVGGETAEHP GLLGPDDFDV AGAGTGVVEA DRLLGPDRIR 190 200 210 220 230 240 EGDAVIAMAS SGLHSNGYSL VRHVVFDRAG WSLDREVEEF GRTLGEELLE PTRIYSLDCL 250 260 270 280 290 300 ALTRTTEVHG FSHVTGGGLA NNLARVIPDG LHATVDRSTW TPGAVFDLVG KAGRVERLEL 310 320 330 340 350 EKTLNMGVGM IAIVPADSVD AALTTLADRG VDSWVAGEIT ARGEHTTGAE LTGDYAR

References

[1]

"Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350." Ohnishi Y., Ishikawa J., Hara H., Suzuki H., Ikenoya M., Ikeda H., Yamashita A., Hattori M., Horinouchi S. J. Bacteriol. 190:4050-4060(2008) [PubMed: 18375553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009493 Genomic DNA. Translation: BAG20707.1.
RefSeq	YP_001825390.1. NC_010572.1.
3D structure databases
ProteinModelPortal	B1VR56.
ModBase	Search...
Protein-protein interaction databases
STRING	B1VR56.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6214384.
GenomeReviews	Gene locus SGR_3878 in contig AP009493_GR.
KEGG	sgr:SGR_3878.
PATRIC	23754332. VBIStrGri32265_3945.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG531222.
OMA	PENIPRV.
ProtClustDB	PRK05385.
Family and domain databases
InterPro	IPR000728. AIR_synth. IPR010918. AIR_synth_C. IPR004733. PurM_cligase. IPR016188. PurM_N-like. [Graphical view]
KO	K01933.
Pfam	PF00586. AIRS. 1 hit. PF02769. AIRS_C. 1 hit. [Graphical view]
SUPFAM	SSF56042. AIR_synth_C. 1 hit. SSF55326. PurM_N-like. 1 hit.
TIGRFAMs	TIGR00878. PurM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B1VR56_STRGG

Accession

Primary (citable) accession number: B1VR56

Entry history

Integrated into UniProtKB/TrEMBL:	May 20, 2008
Last sequence update:	May 20, 2008
Last modified:	December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)