B1VP97 (PATR_STRGG) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative phenylalanine aminotransferase
EC=2.6.1.-

Gene names

Name:	pat
Ordered Locus Names:	SGR_3647

Organism

Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350) [Complete proteome] [HAMAP]

Taxonomic identifier

455632 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length	359 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May catalyze the transamination reaction in phenylalanine biosynthesis By similarity. HAMAP MF_01513
Cofactor	Pyridoxal phosphate By similarity. HAMAP MF_01513
Sequence similarities	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

Ontologies

Keywords
Ligand	Pyridoxal phosphate
Molecular function	Aminotransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	histidine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	1-aminocyclopropane-1-carboxylate synthase activity Inferred from electronic annotation. Source: InterPro histidinol-phosphate transaminase activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 359	359	Putative phenylalanine aminotransferase HAMAP MF_01513		PRO_1000146152
Amino acid modifications
	Modified residue	223	1	N6-(pyridoxal phosphate)lysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	B1VP97 [UniParc]. Last modified May 20, 2008. Version 1. Checksum: C8FD1B514719CD9C	FASTA	359	38,332
	10 20 30 40 50 60 MSETSPKLRA ELDGVPAYVP GKPAAAGGPV AYKLSSNENP YPPLPGVLES ALAAAGSFNR 70 80 90 100 110 120 YPDMACTGLM NELADRFGVP LGHLATGTGS VGVAQQLLQA TSGPGDEVIY AWRSFEAYPI 130 140 150 160 170 180 ITQVSGATSV KVPLTDGEVH DLDAMAEAIT DRTRLIFVCN PNNPTGTVVR RAELERFLDR 190 200 210 220 230 240 VPSDVLVVLD EAYKEFIRDA EVPDGIEIYR DRPNVAVLRT FSKAYGLAGL RVGFAVAHEP 250 260 270 280 290 300 VAAALRKTAV PFGVSQLAQD AAVASLRAED ELLGRVGSLV AERTRVSAEL TRQGWTVPES 310 320 330 340 350 HANFVWLRLG ERTLDFAGAC ERAGVVVRPF QGEGVRVSIG EGEGNDLFLK AAEAFRAEL

References

[1]

"Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350." Ohnishi Y., Ishikawa J., Hara H., Suzuki H., Ikenoya M., Ikeda H., Yamashita A., Hattori M., Horinouchi S. J. Bacteriol. 190:4050-4060(2008) [PubMed: 18375553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JCM 4626 / NBRC 13350.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009493 Genomic DNA. Translation: BAG20476.1.
RefSeq	YP_001825159.1. NC_010572.1.
3D structure databases
ProteinModelPortal	B1VP97.
ModBase	Search...
Protein-protein interaction databases
STRING	B1VP97.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6209659.
GenomeReviews	Gene locus SGR_3647 in contig AP009493_GR.
KEGG	sgr:SGR_3647.
PATRIC	23753860. VBIStrGri32265_3715.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG646350.
OMA	SSNEVAF.
ProtClustDB	PRK03321.
Family and domain databases
HAMAP	MF_01513. Phe_aminotrans_2. [Tree]
InterPro	IPR001176. ACC_synthase. IPR001917. Aminotrans_II_pyridoxalP_BS. IPR004839. Aminotransferase_I/II. IPR024892. AroT. IPR005861. HisP_aminotrans. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00817.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
PRINTS	PR00753. ACCSYNTHASE.
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01141. HisC. 1 hit.
PROSITE	PS00599. AA_TRANSFER_CLASS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PATR_STRGG

Accession

Primary (citable) accession number: B1VP97

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	May 20, 2008
Last modified:	January 25, 2012
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program