B1VMF9 (DCD_STRGG) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	SGR_3440

Organism

Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350) [Complete proteome] [HAMAP]

Taxonomic identifier

455632 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces › Streptomyces griseus group › Streptomyces griseus › Streptomyces griseus subsp. griseus

Protein attributes

Sequence length	191 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP-Rule MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP-Rule MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	dUMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 191	191	Deoxycytidine triphosphate deaminase HAMAP-Rule MF_00146		PRO_1000096455

Sequences

	Sequence		Length	Mass (Da)
	B1VMF9 [UniParc]. Last modified May 20, 2008. Version 1. Checksum: 7C14B5E4698A8959	FASTA	191	21,468
	10 20 30 40 50 60 MLLSDKDIRA EIDAGRVRID PYDPSMVQPS SIDVRLDRYF RVFENHRYPH IDPAVEQPDL 70 80 90 100 110 120 TRTVEPEGDE AFILHPGEFV LASTYEVISL PDDLASRLEG KSSLGRLGLV THSTAGFIDP 130 140 150 160 170 180 GFSGHVTLEL SNLATLPIKL WPGMKIGQLC LFKLTSSAEF PYGSERYESR YQGQRGPTAS 190 RSFQNFHRTQ V

References

[1]

"Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350." Ohnishi Y., Ishikawa J., Hara H., Suzuki H., Ikenoya M., Ikeda H., Yamashita A., Hattori M., Horinouchi S. J. Bacteriol. 190:4050-4060(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JCM 4626 / NBRC 13350.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009493 Genomic DNA. Translation: BAG20269.1.
RefSeq	YP_001824952.1. NC_010572.1.
3D structure databases
ProteinModelPortal	B1VMF9.
SMR	B1VMF9. Positions 1-189.
ModBase	Search...
Protein-protein interaction databases
STRING	455632.SGR_3440.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAG20269; BAG20269; SGR_3440.
GeneID	6215491.
KEGG	sgr:SGR_3440.
PATRIC	23753454. VBIStrGri32265_3516.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
HOGENOM	HOG000228601.
KO	K01494.
OMA	RQDAKYK.
ProtClustDB	PRK00416.
Enzyme and pathway databases
UniPathway	UPA00610; UER00665.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase.
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_STRGG

Accession

Primary (citable) accession number: B1VMF9

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	May 20, 2008
Last modified:	May 1, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program