Skip Header

Contribute Send feedback
Read comments (?) or add your own

B1VIJ3 (B1VIJ3_CORU7) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Amidophosphoribosyltransferase PIRNR PIRNR000485
Short name=ATase PIRNR PIRNR000485
EC=2.4.2.14 PIRNR PIRNR000485
Alternative name(s):
Glutamine phosphoribosylpyrophosphate amidotransferase PIRNR PIRNR000485
Gene names
Ordered Locus Names:cu1617
OrganismCorynebacterium urealyticum (strain ATCC 43042 / DSM 7109) [Complete proteome] [HAMAP]
Taxonomic identifier504474 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length536 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-phospho-beta-D-ribosylamine + diphosphate + L-glutamate = L-glutamine + 5-phospho-alpha-D-ribose 1-diphosphate + H2O. PIRNR PIRNR000485

Cofactor

Binds 1 4Fe-4S cluster per subunit By similarity. PIRSR PIRSR000485-3

Binds 1 magnesium ion per subunit By similarity. PIRNR PIRNR000485

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2. PIRNR PIRNR000485

Sequence similarities

In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. PIRNR PIRNR000485

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site461For GATase activity By similarity PIRSR PIRSR000485-1
Metal binding2851Iron-sulfur (4Fe-4S) By similarity PIRSR PIRSR000485-3
Metal binding4311Iron-sulfur (4Fe-4S) By similarity PIRSR PIRSR000485-3
Metal binding4861Iron-sulfur (4Fe-4S) By similarity PIRSR PIRSR000485-3
Metal binding4891Iron-sulfur (4Fe-4S) By similarity PIRSR PIRSR000485-3

Sequences

Sequence LengthMass (Da)Tools
B1VIJ3 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: 73FF98A3B55992C4

FASTA53657,571
        10         20         30         40         50         60 
MIVAKDTGLN SLNGTNSAPS VDAAQPAQPA DRGYDDHGEQ PPREECGVFG VWAPGEDVSK 

        70         80         90        100        110        120 
LTYYGLYALQ HRGQEAAGIG VGSGDQILVY KDLGLVSQVF DEQILNSLKG HIAIGHTRYA 

       130        140        150        160        170        180 
TAGGGRWENA QPMFRMASDG TDVALGHNGN LTNYLELMAE AAEKRLVNPA DEPSDSDVMC 

       190        200        210        220        230        240 
ALIADLIDEN TSMEDAALQL FPRVKGAYCL TFTDGKGLYA VRDPHGVRPL SIGKLANGWV 

       250        260        270        280        290        300 
VSSETAALDI VGAEFVRDVE PGEFIAINED GIRSRKFAEA TPKGCVFEYV YLARPDSVIN 

       310        320        330        340        350        360 
GQPVNATRVD IGRRLAEEWP AEGDLVIPVP DSGTPAAVGY AQASGIPFGQ GLTKNAYVGR 

       370        380        390        400        410        420 
TFIEPSQTIR QLGIRLKLNP LRHVIEGKRL IVVDDSIVRG NTQRALIRML RDAGAAEVHV 

       430        440        450        460        470        480 
RIASPPVKWP CFYGIDFPSP NELLANNVDP DNMVEAMREE VGADSLGFVS TEAMVETSAQ 

       490        500        510        520        530 
PRETLCAACF DGVYPLGLPA GNPNAEQVRL RQRRLAEEAE QAAGGSDASS NNPEEN

« Hide

References

[1]"The lifestyle of Corynebacterium urealyticum derived from its complete genome sequence established by pyrosequencing."
Tauch A., Trost E., Tilker A., Ludewig U., Schneiker S., Goesmann A., Arnold W., Bekel T., Brinkrolf K., Brune I., Goetker S., Kalinowski J., Kamp P.-B., Lobo F.P., Viehoever P., Weisshaar B., Soriano F., Droege M., Puehler A.
J. Biotechnol. 136:11-21(2008) [PubMed: 18367281] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43042 / DSM 7109.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM942444 Genomic DNA. Translation: CAQ05577.1.
RefSeqYP_001801011.1. NC_010545.1.

3D structure databases

ProteinModelPortalB1VIJ3.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1VIJ3.

Protein family/group databases

MEROPSC44.001.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6185664.
GenomeReviewsGene locus cu1617 in contig AM942444_GR.
KEGGcur:cur_1617.
PATRIC21522998. VBICorUre58120_1602.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG392416.
OMAVWAPGEE.
ProtClustDBPRK07847.

Family and domain databases

InterProIPR005854. Amd_phspho_trans.
IPR000583. GATase_2.
IPR017932. GATase_II.
IPR000836. PRibTrfase.
[Graphical view]
KOK00764.
PANTHERPTHR11907. Amd_phspho_trans. 1 hit.
PfamPF00310. GATase_2. 1 hit.
PF00156. Pribosyltran. 1 hit.
[Graphical view]
PIRSFPIRSF000485. Amd_phspho_trans. 1 hit.
TIGRFAMsTIGR01134. PurF. 1 hit.
PROSITEPS51278. GATASE_TYPE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB1VIJ3_CORU7
AccessionPrimary (citable) accession number: B1VIJ3
Entry history
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: January 25, 2012
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info