B1VHV2 (B1VHV2_CORU7) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aminomethyltransferase HAMAP MF_00259 RuleBase RU003981
EC=2.1.2.10 HAMAP MF_00259 RuleBase RU003981

Alternative name(s):
Glycine cleavage system T protein HAMAP MF_00259

Gene names

Name:	gcvT HAMAP MF_00259
Ordered Locus Names:	cu1793

Organism

Corynebacterium urealyticum (strain ATCC 43042 / DSM 7109) [Complete proteome] [HAMAP]

Taxonomic identifier

504474 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	396 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The glycine cleavage system catalyzes the degradation of glycine By similarity. HAMAP MF_00259 RuleBase RU003981 SAAS SAAS022903
Catalytic activity	[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. HAMAP MF_00259 RuleBase RU003981 SAAS SAAS022903
Subunit structure	The glycine cleavage system is composed of four proteins: P, T, L and H By similarity. HAMAP MF_00259 RuleBase RU003981 SAAS SAAS022903
Sequence similarities	Belongs to the GcvT family. HAMAP MF_00259 RuleBase RU003980

Ontologies

Keywords
Molecular function	Aminotransferase HAMAP MF_00259 RuleBase RU003981 SAAS SAAS022903 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine decarboxylation via glycine cleavage system Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	aminomethyltransferase activity Inferred from electronic annotation. Source: HAMAP transaminase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1VHV2 [UniParc]. Last modified May 20, 2008. Version 1. Checksum: 942070932D43E2FB	FASTA	396	41,832
	10 20 30 40 50 60 MTDSASTPKH TALHQVHEQL GARFTDFGGW DMPLKYGKEL DEHRAVRETV GVFDLSHMGE 70 80 90 100 110 120 VEVSGPQAAE LLDYALISRL SAVKVGKAKY SMLCTEDGGI VDDLITYRLA DDDFLVVPNA 130 140 150 160 170 180 GNAPRVAEAL AQRAEGFDVT VVDQTAEKSL VAIQGPKAAE VMHAIVENVT DAPEASGATE 190 200 210 220 230 240 DVRGAVDGLG YYAAFKGIVA GQPALIARTG YTGEDGFEII VDNDAAEQVW NIALAKATEL 250 260 270 280 290 300 DGLPCGLAAR DTLRLEAGMP LYGNELNDEL TPVDAGLGIL AATKSKDSFV GRDAIVAAKE 310 320 330 340 350 360 KGAARVLIGL QGEGRRAARS GYAVLAGEGE DAQPIGEVTS GALSPTLGYP VAMAYVDKTA 370 380 390 TEEGGAATVG QTVQVDIRGK QYPYQVVEMP FYQREK

References

[1]

"The lifestyle of Corynebacterium urealyticum derived from its complete genome sequence established by pyrosequencing." Tauch A., Trost E., Tilker A., Ludewig U., Schneiker S., Goesmann A., Arnold W., Bekel T., Brinkrolf K., Brune I., Goetker S., Kalinowski J., Kamp P.-B., Lobo F.P., Viehoever P., Weisshaar B., Soriano F., Droege M., Puehler A. J. Biotechnol. 136:11-21(2008) [PubMed: 18367281] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43042 / DSM 7109.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM942444 Genomic DNA. Translation: CAQ05752.1.
RefSeq	YP_001801186.1. NC_010545.1.
3D structure databases
ProteinModelPortal	B1VHV2.
ModBase	Search...
Protein-protein interaction databases
STRING	B1VHV2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6185059.
GenomeReviews	Gene locus cu1793 in contig AM942444_GR.
KEGG	cur:cur_1793.
PATRIC	21523340. VBICorUre58120_1773.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG299834.
OMA	GWEMPIS.
ProtClustDB	PRK00389.
Family and domain databases
HAMAP	MF_00259. GcvT. [Tree]
InterPro	IPR013977. GCV_T_C. IPR006222. GCV_T_N. IPR006223. GcvT. IPR022903. NH2_Me_Trfase. [Graphical view]
KO	K00605.
PANTHER	PTHR13847:SF5. PTHR13847:SF5. 1 hit.
Pfam	PF01571. GCV_T. 1 hit. PF08669. GCV_T_C. 1 hit. [Graphical view]
PIRSF	PIRSF006487. GcvT. 1 hit.
TIGRFAMs	TIGR00528. GcvT. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B1VHV2_CORU7

Accession

Primary (citable) accession number: B1VHV2

Entry history

Integrated into UniProtKB/TrEMBL:	May 20, 2008
Last sequence update:	May 20, 2008
Last modified:	January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)