B1VHD7 (B1VHD7_CORU7) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Methylenetetrahydrofolate reductase RuleBase RU003862
EC=1.5.1.20 RuleBase RU003862

Gene names

Ordered Locus Names:

cu1218

Organism

Corynebacterium urealyticum (strain ATCC 43042 / DSM 7109) [Complete proteome] [HAMAP]

Taxonomic identifier

504474 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	348 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H. RuleBase RU003862
Cofactor	FAD By similarity. RuleBase RU003862
Pathway	One-carbon metabolism; tetrahydrofolate pathway. RuleBase RU004255
Sequence similarities	Belongs to the methylenetetrahydrofolate reductase family. RuleBase RU003862

Ontologies

Keywords
Biological process	Amino-acid biosynthesis RuleBase RU004255
Ligand	FAD RuleBase RU003862 Flavoprotein RuleBase RU003862
Molecular function	Oxidoreductase RuleBase RU003862 EMBL CAQ05178.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular amino acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW methionine metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	methylenetetrahydrofolate reductase (NADPH) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1VHD7 [UniParc]. Last modified May 20, 2008. Version 1. Checksum: 9E9CD44D4A42BF5C	FASTA	348	38,199
	10 20 30 40 50 60 MSTMISFMSA SNPHDHHEKA SPLPGIPPQP TLQVPVSQAI RGYSPGKIPF SVEFMPPRDD 70 80 90 100 110 120 AAQTRLWNAA EAFHDLGVSF ASITYGAGGS TRERTMEVAQ QLAAKPLTTL MHLTLVDHSA 130 140 150 160 170 180 EELRAMLQDY ARRGMTNVLA LRGDPPGDPL GTWQPTPGGL NYASDLIELI RNTPECENFD 190 200 210 220 230 240 IGIASFPEGH YRAEDLEQDT QVTLHKLRLG ADYSITQMFF DVENYLRLRD RLAAADPVHG 250 260 270 280 290 300 AKPVIPGLMP ITSIRSVRRQ MELAGGEVPV KILERLEKAA AGDEVANRDA VREVGIDITT 310 320 330 340 EMSERLIAEG APNLHFMTMN NVRATQDVLH NLGMAPAWGP GYGQDMVR

References

[1]

"The lifestyle of Corynebacterium urealyticum derived from its complete genome sequence established by pyrosequencing." Tauch A., Trost E., Tilker A., Ludewig U., Schneiker S., Goesmann A., Arnold W., Bekel T., Brinkrolf K., Brune I., Goetker S., Kalinowski J., Kamp P.-B., Lobo F.P., Viehoever P., Weisshaar B., Soriano F., Droege M., Puehler A. J. Biotechnol. 136:11-21(2008) [PubMed: 18367281] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43042 / DSM 7109.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM942444 Genomic DNA. Translation: CAQ05178.1.
RefSeq	YP_001800612.1. NC_010545.1.
3D structure databases
ProteinModelPortal	B1VHD7.
ModBase	Search...
Protein-protein interaction databases
STRING	B1VHD7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6186410.
GenomeReviews	Gene locus cu1218 in contig AM942444_GR.
KEGG	cur:cur_1218.
PATRIC	21522206. VBICorUre58120_1226.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG649727.
OMA	ITQMFFD.
ProtClustDB	CLSK638719.
Family and domain databases
InterPro	IPR003171. Mehydrof_redctse. [Graphical view]
KO	K00297.
Pfam	PF02219. MTHFR. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B1VHD7_CORU7

Accession

Primary (citable) accession number: B1VHD7

Entry history

Integrated into UniProtKB/TrEMBL:	May 20, 2008
Last sequence update:	May 20, 2008
Last modified:	January 25, 2012
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)