B1VH94 (B1VH94_CORU7) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Histidinol-phosphate aminotransferase HAMAP MF_01023
EC=2.6.1.9 HAMAP MF_01023

Alternative name(s):
Imidazole acetol-phosphate transaminase HAMAP MF_01023

Gene names

Name:	hisC HAMAP MF_01023
Ordered Locus Names:	cu1175

Organism

Corynebacterium urealyticum (strain ATCC 43042 / DSM 7109) [Complete proteome] [HAMAP]

Taxonomic identifier

504474 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	362 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate. HAMAP MF_01023 SAAS SAAS005861
Cofactor	Pyridoxal phosphate By similarity. HAMAP MF_01023 SAAS SAAS005861
Pathway	Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9. HAMAP MF_01023 SAAS SAAS005861
Subunit structure	Homodimer By similarity. HAMAP MF_01023
Sequence similarities	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. HAMAP MF_01023

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Histidine biosynthesis HAMAP MF_01023 SAAS SAAS005861
Ligand	Pyridoxal phosphate HAMAP MF_01023 SAAS SAAS005861
Molecular function	Aminotransferase HAMAP MF_01023 SAAS SAAS005861 EMBL CAQ05135.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	histidine biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	L-phenylalanine:2-oxoglutarate aminotransferase activity Inferred from electronic annotation. Source: EC histidinol-phosphate transaminase activity Inferred from electronic annotation. Source: HAMAP pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Amino acid modifications
	Modified residue	225	1	N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01023

Sequences

	Sequence		Length	Mass (Da)
	B1VH94 [UniParc]. Last modified May 20, 2008. Version 1. Checksum: 706084BC0F07FD78	FASTA	362	39,320
	10 20 30 40 50 60 MVNLPIREEF QGKSAYGAPQ LTVKNQLNTN ENPYPPSEAI VEDLVAEVRA LGTGLNRYPE 70 80 90 100 110 120 RDAVELREDL ADYITAQTGV AVTKDNLWAA NGSNEILQQL LQVFGGPGRS VLGFVPSYSM 130 140 150 160 170 180 HPILAAGTQT EFIAIDRDPA QGFAIDVDKA VAAIEQHQPN IVFVTTPNNP TGGITPLADI 190 200 210 220 230 240 RRILDAAPGV VIIDEAYAEF SDEPSACTLL ADYPAKLVVS RTMSKAFDFA GGRLGYFVAD 250 260 270 280 290 300 PAFIESVMLV RLPYHLSTLS QAAARVALRH REDTLATVAT LSEQRDRVAA ELKELGYEVV 310 320 330 340 350 360 DSHSNFIFFG GLQDSHRTWE AFLDQDVLIR DVGIPGWLRV TIGLPEENDA FLAAAAAVKG KN

References

[1]

"The lifestyle of Corynebacterium urealyticum derived from its complete genome sequence established by pyrosequencing." Tauch A., Trost E., Tilker A., Ludewig U., Schneiker S., Goesmann A., Arnold W., Bekel T., Brinkrolf K., Brune I., Goetker S., Kalinowski J., Kamp P.-B., Lobo F.P., Viehoever P., Weisshaar B., Soriano F., Droege M., Puehler A. J. Biotechnol. 136:11-21(2008) [PubMed: 18367281] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43042 / DSM 7109.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM942444 Genomic DNA. Translation: CAQ05135.1.
RefSeq	YP_001800569.1. NC_010545.1.
3D structure databases
ProteinModelPortal	B1VH94.
ModBase	Search...
Protein-protein interaction databases
STRING	B1VH94.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6186695.
GenomeReviews	Gene locus cu1175 in contig AM942444_GR.
KEGG	cur:cur_1175.
PATRIC	21522112. VBICorUre58120_1179.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG646350.
OMA	GRTAIGF.
ProtClustDB	PRK03317.
Family and domain databases
HAMAP	MF_01023. HisC_aminotrans_2. [Tree]
InterPro	IPR004839. Aminotransferase_I/II. IPR005861. HisP_aminotrans. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00817.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01141. HisC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B1VH94_CORU7

Accession

Primary (citable) accession number: B1VH94

Entry history

Integrated into UniProtKB/TrEMBL:	May 20, 2008
Last sequence update:	May 20, 2008
Last modified:	January 25, 2012
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)