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B1VH38 (B1VH38_CORU7) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phenylalanine--tRNA ligase alpha chain HAMAP MF_00281

EC=6.1.1.20 HAMAP MF_00281
Alternative name(s):
Phenylalanyl-tRNA synthetase alpha chain HAMAP MF_00281
Gene names
Name:pheS HAMAP MF_00281
Ordered Locus Names:cu1119
OrganismCorynebacterium urealyticum (strain ATCC 43042 / DSM 7109) [Complete proteome] [HAMAP]
Taxonomic identifier504474 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium

Protein attributes

Sequence length353 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe). HAMAP MF_00281

Cofactor

Binds 2 magnesium ions per tetramer By similarity. HAMAP MF_00281

Subunit structure

Tetramer of two alpha and two beta chains By similarity. HAMAP MF_00281

Subcellular location

Cytoplasm By similarity HAMAP MF_00281.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily. HAMAP MF_00281

Sequences

Sequence LengthMass (Da)Tools
B1VH38 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: B9819698DDEE5153

FASTA35338,925
        10         20         30         40         50         60 
MSESPVSPEA AVEISEESMG AAAEAAEKAF TSATNLEELA EARRAHLGDD APIPAARRSL 

        70         80         90        100        110        120 
GSLPKDQRKD AGRIVNMARG RVEKLFAQVK AELEEKRNQE ALRAERIDVT QPTTRGQVGA 

       130        140        150        160        170        180 
QHPITILNEQ IADIFVGMGW EIADGPEVEA EYFNFDSLNF IPDHPARTLQ DTFHIAPQGS 

       190        200        210        220        230        240 
RQVLRTHTSP VQMRTMLSRE VPVYIACPGR VFRTDELDAT HTPVFHQVEG LAVDKGLTMA 

       250        260        270        280        290        300 
HLKGTLDHLA KSLFGPNTKT RIRPNYFPFT EPSAEVDVWF EDKKGGAGWI EWGGCGMVNP 

       310        320        330        340        350 
NVLIAAGIDP EEYSGFAFGM GIERTLQFRN GLPDMRDMVE GDVRFTLPFG VRG 

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References

[1]"The lifestyle of Corynebacterium urealyticum derived from its complete genome sequence established by pyrosequencing."
Tauch A., Trost E., Tilker A., Ludewig U., Schneiker S., Goesmann A., Arnold W., Bekel T., Brinkrolf K., Brune I., Goetker S., Kalinowski J., Kamp P.-B., Lobo F.P., Viehoever P., Weisshaar B., Soriano F., Droege M., Puehler A.
J. Biotechnol. 136:11-21(2008) [PubMed: 18367281] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43042 / DSM 7109.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM942444 Genomic DNA. Translation: CAQ05079.1.
RefSeqYP_001800513.1. NC_010545.1.

3D structure databases

ProteinModelPortalB1VH38.
SMRB1VH38. Positions 101-349.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1VH38.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6186511.
GenomeReviewsGene locus cu1119 in contig AM942444_GR.
KEGGcur:cur_1119.
PATRIC21521990. VBICorUre58120_1119.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG284353.
OMAFRASYFP.
ProtClustDBPRK00488.

Family and domain databases

HAMAPMF_00281. Phe_tRNA_synth_alpha1.
[Tree]
InterProIPR006195. aa-tRNA-synth_II.
IPR004529. Phe-tRNA-synth_IIc_asu.
IPR004188. Phe-tRNA_synth_II_N.
IPR022911. Phe_tRNA_synth_alpha1_bac.
IPR002319. Phenylalanyl-tRNA_Synthase.
IPR010978. tRNA-bd_arm.
[Graphical view]
KOK01889.
PfamPF02912. Phe_tRNA-synt_N. 1 hit.
PF01409. tRNA-synt_2d. 1 hit.
[Graphical view]
SUPFAMSSF46589. tRNA_binding_arm. 1 hit.
TIGRFAMsTIGR00468. PheS. 1 hit.
PROSITEPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB1VH38_CORU7
AccessionPrimary (citable) accession number: B1VH38
Entry history
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)