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B1VGL8 (B1VGL8_CORU7) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutamate 5-kinase HAMAP MF_00456
EC=2.7.2.11 HAMAP MF_00456
Alternative name(s):
Gamma-glutamyl kinase HAMAP MF_00456
Gene names
Name:proB HAMAP MF_00456
Ordered Locus Names:cu1365
OrganismCorynebacterium urealyticum (strain ATCC 43042 / DSM 7109) [Complete proteome] [HAMAP]
Taxonomic identifier504474 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length376 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5-oxoproline By similarity. HAMAP MF_00456 SAAS SAAS011529

Catalytic activity

ATP + L-glutamate = ADP + L-glutamate 5-phosphate. HAMAP MF_00456 SAAS SAAS011529

Pathway

Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2. SAAS SAAS011529 HAMAP MF_00456

Subcellular location

Cytoplasm By similarity HAMAP MF_00456 SAAS SAAS011529.

Sequence similarities

Belongs to the glutamate 5-kinase family. HAMAP MF_00456

Contains 1 PUA domain. HAMAP MF_00456 SAAS SAAS011529

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain275 – 35379PUA By similarity HAMAP MF_00456

Sequences

Sequence LengthMass (Da)Tools
B1VGL8 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: 756C7DA2AD87D383

FASTA37640,325
        10         20         30         40         50         60 
MRHRIANAKR LVVKIGSSSL TDESGRVDPA RIDTIADALE ARMSDDTDLI VVSSGAVASG 

        70         80         90        100        110        120 
MDPLGLRQRP SDLATKQAAA SVGQVLLAQE WGRSFARYGR TIGQVLLTAA DAGRRDRARN 

       130        140        150        160        170        180 
AQRTIDRLRQ LSAVPIVNEN DTVATSEMRF GDNDRLAAIV SHLVFADALV LLSDVDGLYD 

       190        200        210        220        230        240 
RNPNEPDAQF VSEVRSSNDL SGVAAGDGGR LGTGGMAAKV TAARLASRAG VPVLLTSTEN 

       250        260        270        280        290        300 
IAPALESASV GTCFWPEEDR LSAWKFWVLY AAESRGALQL DDGAKKAVVD GNKSLLAVGV 

       310        320        330        340        350        360 
TQVMGDFNRG DIVDLVDSEG KIFGRGEVNY DATDLAPMLG RHTSELPGDA QRPVIHTDYL 

       370 
SYYANRQPPR RQQLPI

« Hide

References

[1]"The lifestyle of Corynebacterium urealyticum derived from its complete genome sequence established by pyrosequencing."
Tauch A., Trost E., Tilker A., Ludewig U., Schneiker S., Goesmann A., Arnold W., Bekel T., Brinkrolf K., Brune I., Goetker S., Kalinowski J., Kamp P.-B., Lobo F.P., Viehoever P., Weisshaar B., Soriano F., Droege M., Puehler A.
J. Biotechnol. 136:11-21(2008) [PubMed: 18367281] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43042 / DSM 7109.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM942444 Genomic DNA. Translation: CAQ05325.1.
RefSeqYP_001800759.1. NC_010545.1.

3D structure databases

ProteinModelPortalB1VGL8.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1VGL8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6185820.
GenomeReviewsGene locus cu1365 in contig AM942444_GR.
KEGGcur:cur_1365.
PATRIC21522488. VBICorUre58120_1363.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG507643.
OMATFGDNDM.
ProtClustDBPRK05429.

Family and domain databases

HAMAPMF_00456. ProB.
[Tree]
InterProIPR001048. Asp/Glu/Uridylate_kinase.
IPR001057. Glu/AcGlu_kinase.
IPR011529. Glu_5kinase.
IPR005715. Glu_5kinase/COase_Synthase.
IPR019797. Glutamate_5-kinase_CS.
IPR002478. PUA.
IPR015947. PUA-like_domain.
[Graphical view]
Gene3DG3DSA:3.40.1160.10. Aa_kinase. 1 hit.
KOK00931.
PfamPF00696. AA_kinase. 1 hit.
PF01472. PUA. 1 hit.
[Graphical view]
PIRSFPIRSF000729. GK. 1 hit.
PRINTSPR00474. GLU5KINASE.
SMARTSM00359. PUA. 1 hit.
[Graphical view]
SUPFAMSSF53633. Aa_kinase. 1 hit.
SSF88697. PUA-like. 1 hit.
TIGRFAMsTIGR01027. ProB. 1 hit.
PROSITEPS00902. GLUTAMATE_5_KINASE. 1 hit.
PS50890. PUA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB1VGL8_CORU7
AccessionPrimary (citable) accession number: B1VGL8
Entry history
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: January 25, 2012
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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