B1VG82 (B1VG82_CORU7) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Ribonuclease HII HAMAP MF_00052
Short name=RNase HII HAMAP MF_00052
EC=3.1.26.4 HAMAP MF_00052

Gene names

Name:	rnhB HAMAP MF_00052
Ordered Locus Names:	cu0811

Organism

Corynebacterium urealyticum (strain ATCC 43042 / DSM 7109) [Complete proteome] [HAMAP]

Taxonomic identifier

504474 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	241 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Endonuclease that specifically degrades the RNA of RNA-DNA hybrids By similarity. RuleBase RU003515 HAMAP MF_00052
Catalytic activity	Endonucleolytic cleavage to 5'-phosphomonoester. RuleBase RU003515 HAMAP MF_00052
Cofactor	Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding By similarity. HAMAP MF_00052
Subcellular location	Cytoplasm By similarity HAMAP MF_00052.
Sequence similarities	Belongs to the RNase HII family. RuleBase RU003515 HAMAP MF_00052

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00052
Ligand	Manganese HAMAP MF_00052 Metal-binding HAMAP MF_00052
Molecular function	Endonuclease RuleBase RU003515 HAMAP MF_00052 Hydrolase Nuclease
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	RNA catabolic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	RNA binding Inferred from electronic annotation. Source: InterPro manganese ion binding Inferred from electronic annotation. Source: HAMAP ribonuclease H activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Metal binding	45	1	Divalent metal cation By similarity HAMAP MF_00052
	Metal binding	46	1	Divalent metal cation By similarity HAMAP MF_00052
	Metal binding	139	1	Divalent metal cation By similarity HAMAP MF_00052

Sequences

	Sequence		Length	Mass (Da)
	B1VG82 [UniParc]. Last modified May 20, 2008. Version 1. Checksum: 6CA011802ED0F5CD	FASTA	241	25,795
	10 20 30 40 50 60 MARPTPQSAA RARGAELVQQ ALSEGYSFVD DYLRFHGFSH VAGVDEAGRG ACCGPITIAS 70 80 90 100 110 120 CILPDHGVPE LAGLNDSKKL TPKRRERLFG AITEHAVAYE IVHIPAAEID QRGIQYANIN 130 140 150 160 170 180 GMYRVVAGLG VEPDVVLTDA VHLPELACEH APLVKGDALS PAISAASILA KVSRDRLMVE 190 200 210 220 230 240 MAEKYPGYGL AGHKGYGTAK HMAAVRLHGA CPEHRYTYSN VATAHAEWAS TQPREEGHPG Q

References

[1]

"The lifestyle of Corynebacterium urealyticum derived from its complete genome sequence established by pyrosequencing." Tauch A., Trost E., Tilker A., Ludewig U., Schneiker S., Goesmann A., Arnold W., Bekel T., Brinkrolf K., Brune I., Goetker S., Kalinowski J., Kamp P.-B., Lobo F.P., Viehoever P., Weisshaar B., Soriano F., Droege M., Puehler A. J. Biotechnol. 136:11-21(2008) [PubMed: 18367281] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43042 / DSM 7109.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM942444 Genomic DNA. Translation: CAQ04771.1.
RefSeq	YP_001800205.1. NC_010545.1.
3D structure databases
ProteinModelPortal	B1VG82.
ModBase	Search...
Protein-protein interaction databases
STRING	B1VG82.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6185822.
GenomeReviews	Gene locus cu0811 in contig AM942444_GR.
KEGG	cur:cur_0811.
PATRIC	21521348. VBICorUre58120_0810.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG584843.
OMA	RLGPTPI.
Family and domain databases
HAMAP	MF_00052_B. RNase_HII_B. [Tree]
InterPro	IPR022898. RNase_HII. IPR001352. RNase_HII/HIII. IPR024567. RNase_HII/HIII_dom. IPR012337. RNaseH-like_dom. [Graphical view]
KO	K03470.
PANTHER	PTHR10954. RNase_HII/HIII. 1 hit.
Pfam	PF01351. RNase_HII. 1 hit. [Graphical view]
SUPFAM	SSF53098. RNaseH_fold. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B1VG82_CORU7

Accession

Primary (citable) accession number: B1VG82

Entry history

Integrated into UniProtKB/TrEMBL:	May 20, 2008
Last sequence update:	May 20, 2008
Last modified:	January 25, 2012
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)