B1VFM4 (B1VFM4_CORU7) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Pantothenate kinase HAMAP MF_00215 RuleBase RU003530
EC=2.7.1.33 HAMAP MF_00215 RuleBase RU003530

Alternative name(s):
Pantothenic acid kinase HAMAP MF_00215

Gene names

Name:	coaA HAMAP MF_00215
Ordered Locus Names:	cu0603

Organism

Corynebacterium urealyticum (strain ATCC 43042 / DSM 7109) [Complete proteome] [HAMAP]

Taxonomic identifier

504474 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	315 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (R)-pantothenate = ADP + (R)-4'-phosphopantothenate. HAMAP MF_00215 RuleBase RU003530 SAAS SAAS004566
Pathway	Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5. HAMAP MF_00215 RuleBase RU003530 SAAS SAAS004566
Subcellular location	Cytoplasm By similarity HAMAP MF_00215 RuleBase RU003530 SAAS SAAS004566.
Sequence similarities	Belongs to the prokaryotic pantothenate kinase family. HAMAP MF_00215 RuleBase RU003530

Ontologies

Keywords
Biological process	Coenzyme A biosynthesis HAMAP MF_00215 RuleBase RU003530 SAAS SAAS004566
Cellular component	Cytoplasm HAMAP MF_00215 RuleBase RU003530 SAAS SAAS004566
Ligand	ATP-binding HAMAP MF_00215 RuleBase RU003528 SAAS SAAS004566 Nucleotide-binding
Molecular function	Kinase HAMAP MF_00215 RuleBase RU003528 SAAS SAAS004566 EMBL CAQ04563.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme A biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP pantothenate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	100 – 107	8	ATP By similarity HAMAP MF_00215

Sequences

	Sequence		Length	Mass (Da)
	B1VFM4 [UniParc]. Last modified May 20, 2008. Version 1. Checksum: C9372E503E466117	FASTA	315	35,882
	10 20 30 40 50 60 MNRTPQRASA DATESPFIEL KRSQWRELRK SMPQVLSESE LDQLRGIGDE IDLDEVSEVY 70 80 90 100 110 120 LPLSRLINLR VEAQRSLNQA TETFIGEPMP PTPYIIGVSG SVAVGKSTTA RVLQVLLQRW 130 140 150 160 170 180 DSSPRVDLIT TDGFLFPTAE LERRRLLHRK GFPESYDQQA LLNFVTKVKS GARNVKAPVY 190 200 210 220 230 240 SHEAYDRIAG EFEVVDQPDI LIVEGLNVLQ TGPTLMVSDL FDFSVYVDAR VEDIEDWYIS 250 260 270 280 290 300 RFLRLKNTAF KDPEAHFHHL AGLSDEQAAQ VAREIWQTVN LPNLMENILP TRIRASLVMR 310 KGADHLVDRV RMRKI

References

[1]

"The lifestyle of Corynebacterium urealyticum derived from its complete genome sequence established by pyrosequencing." Tauch A., Trost E., Tilker A., Ludewig U., Schneiker S., Goesmann A., Arnold W., Bekel T., Brinkrolf K., Brune I., Goetker S., Kalinowski J., Kamp P.-B., Lobo F.P., Viehoever P., Weisshaar B., Soriano F., Droege M., Puehler A. J. Biotechnol. 136:11-21(2008) [PubMed: 18367281] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43042 / DSM 7109.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM942444 Genomic DNA. Translation: CAQ04563.1.
RefSeq	YP_001799997.1. NC_010545.1.
3D structure databases
ProteinModelPortal	B1VFM4.
SMR	B1VFM4. Positions 15-315.
ModBase	Search...
Protein-protein interaction databases
STRING	B1VFM4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6186409.
GenomeReviews	Gene locus cu0603 in contig AM942444_GR.
KEGG	cur:cur_0603.
PATRIC	21520928. VBICorUre58120_0604.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG732538.
OMA	EVYLPLS.
ProtClustDB	PRK05439.
Family and domain databases
HAMAP	MF_00215. Pantothen_kinase_1. [Tree]
InterPro	IPR004566. PanK_bact. IPR006083. PRK/URK. [Graphical view]
KO	K00867.
PANTHER	PTHR10285:SF7. PanK_bact. 1 hit.
Pfam	PF00485. PRK. 1 hit. [Graphical view]
PIRSF	PIRSF000545. Pantothenate_kin. 1 hit.
TIGRFAMs	TIGR00554. PanK_bact. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B1VFM4_CORU7

Accession

Primary (citable) accession number: B1VFM4

Entry history

Integrated into UniProtKB/TrEMBL:	May 20, 2008
Last sequence update:	May 20, 2008
Last modified:	January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)