B1VF33 (B1VF33_CORU7) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Error-prone DNA polymerase HAMAP MF_01902
EC=2.7.7.7 HAMAP MF_01902

Gene names

Name:	dnaE2 HAMAP MF_01902
Ordered Locus Names:	cu0412

Organism

Corynebacterium urealyticum (strain ATCC 43042 / DSM 7109) [Complete proteome] [HAMAP]

Taxonomic identifier

504474 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	1157 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP MF_01902 SAAS SAAS004013
Subcellular location	Cytoplasm By similarity HAMAP MF_01902 SAAS SAAS004013.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily. HAMAP MF_01902

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP MF_01902 SAAS SAAS004013 DNA replication HAMAP MF_01902 SAAS SAAS004013
Cellular component	Cytoplasm HAMAP MF_01902 SAAS SAAS023073
Molecular function	DNA-directed DNA polymerase HAMAP MF_01902 SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1VF33 [UniParc]. Last modified May 20, 2008. Version 1. Checksum: 956DE9A997AC2CB2	FASTA	1,157	124,766
	10 20 30 40 50 60 MTYTRGFNNP KALSWSRIER ILSGKTTGES VEARSRNEVR RGEQGGGRRV DYSGEVQRGK 70 80 90 100 110 120 RPGGSSGVQA ATGQPSNRAR AAAAHVEFAE LRAASSYHFL HGASEPEELV EQAIALGITA 130 140 150 160 170 180 LACLDRDGMY GAARFATAAA EAEGELKTVF GAELSIDGPQ APGLAVLCRG QEGYRRLSRS 190 200 210 220 230 240 ITAARMAHRD KDAVEYPSFG ELAEAAGGHW LVLIDAAQLS IPGRAAELLE AFGTQHCLVQ 250 260 270 280 290 300 LQLSMDPADV DHNEALHAFA TTHGLREILS SQPTCATPSQ ARLAGAKAAL RRRWDVARAE 310 320 330 340 350 360 PVTHPMGGSW LRSGAELRQL AGDCAWLAEA TATSVDVAEE CAFTLNLVAP ELPHFPVPEG 370 380 390 400 410 420 HSEMSWLREL VERNGTHRYG WRGSTAAAQK AWEVIDRELG VIEKLGFPGY FLIVHDIVDH 430 440 450 460 470 480 CHSNNILCQG RGSAANSAVC FALGITSVDA VAAGLLFERF LSPEREGPPD IDLDIESGRR 490 500 510 520 530 540 EEVIQYVYRR YGRDNAAQVA NVITYRRKGA LRDAARALGY PAGQVDAWTR GAAEAPERVR 550 560 570 580 590 600 QLAEQLIGQA RHLGIHSGGM VICDRPIADV VPTEWARMEN RSVVQWDKDD CAAVGLVKFD 610 620 630 640 650 660 LLGLGMLEAL HHAIDQVATH RGRRIELWRL APTEEAVYEM LSRADAVGVF QVESRAQMNT 670 680 690 700 710 720 LPRLRPRRFY DLVVQVALIR PGPIQGGSVH PFIRRRNGLE PVTFDHPCLE PALSKTLGIP 730 740 750 760 770 780 LFQEQLMQVV VDAAGFTAAE ADTLRRAMGS KRSPERMARL KERFYEGLER TNGITGEVAD 790 800 810 820 830 840 RLWEKITAFA AYGFPESHSQ SFAALVYYSA WFKYHYPAEF CVALLRAQPM GFYSPQSLIA 850 860 870 880 890 900 DARRHGVRIL PVCVNASGAQ ADTDLSAGSA ASPSVSSSSS FKDVNRARGV HGLGRGTAEP 910 920 930 940 950 960 IGAIRLGLAS IAGISEEAAE RIVATREEQG EYRQVSDLSR EAGLSVAQVA ALARAGALES 970 980 990 1000 1010 1020 LGLDRRQAVW AAGLAATERE GMLPGTSAPS VPALPGMSAF ELAAADLAAT SVTPDGHPVE 1030 1040 1050 1060 1070 1080 LLRGQLSQWH DLPVRAGVRR GQRRGGAAVV PAVDLLHVPD GSRIRVAGVI THRQRPATAG 1090 1100 1110 1120 1130 1140 GVVFLGVEDE TGIANVMLTQ GLWKKQRQVA MTARIVVVRG IVHNAEGAAS VTADLLEAVE 1150 PELSGTTALG SPSRDFR

References

[1]

"The lifestyle of Corynebacterium urealyticum derived from its complete genome sequence established by pyrosequencing." Tauch A., Trost E., Tilker A., Ludewig U., Schneiker S., Goesmann A., Arnold W., Bekel T., Brinkrolf K., Brune I., Goetker S., Kalinowski J., Kamp P.-B., Lobo F.P., Viehoever P., Weisshaar B., Soriano F., Droege M., Puehler A. J. Biotechnol. 136:11-21(2008) [PubMed: 18367281] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43042 / DSM 7109.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM942444 Genomic DNA. Translation: CAQ04372.1.
RefSeq	YP_001799806.1. NC_010545.1.
3D structure databases
ProteinModelPortal	B1VF33.
ModBase	Search...
Protein-protein interaction databases
STRING	B1VF33.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6184799.
GenomeReviews	Gene locus cu0412 in contig AM942444_GR.
KEGG	cur:cur_0412.
PATRIC	21520538. VBICorUre58120_0412.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG734490.
OMA	LATNRNG.
ProtClustDB	PRK05672.
Family and domain databases
HAMAP	MF_01902. DNApol_error_prone. [Tree]
InterPro	IPR011708. DNA_pol3_alpha. IPR023073. DNA_pol_error_prone. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. [Graphical view]
KO	K14162.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B1VF33_CORU7

Accession

Primary (citable) accession number: B1VF33

Entry history

Integrated into UniProtKB/TrEMBL:	May 20, 2008
Last sequence update:	May 20, 2008
Last modified:	January 25, 2012
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)