B1VEZ9 (GLMM_CORU7) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	cu0378

Organism

Corynebacterium urealyticum (strain ATCC 43042 / DSM 7109) [Complete proteome] [HAMAP]

Taxonomic identifier

504474 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	446 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 446	446	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_1000201079
Sites
	Active site	103	1	Phosphoserine intermediate By similarity
	Metal binding	103	1	Magnesium; via phosphate group By similarity
	Metal binding	242	1	Magnesium By similarity
	Metal binding	244	1	Magnesium By similarity
	Metal binding	246	1	Magnesium By similarity
Amino acid modifications
	Modified residue	103	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	B1VEZ9 [UniParc]. Last modified May 20, 2008. Version 1. Checksum: 343B22B6119FA4A8	FASTA	446	46,797
	10 20 30 40 50 60 MGRLFGTDGV RGLANEKLTA PLAMRLGAAA ARVLTEKKST DRRPTAIIGR DPRVSGEMLT 70 80 90 100 110 120 AALSAGLASQ GVDVLDVGVL PTPAVAFLTD DYGSDMGVMV SASHNPMPDN GIKFFAIGGR 130 140 150 160 170 180 KLEDWIEDEI EQEMGKLPEE GPTGAAIGRV FDQSHSALDR YLHHLQQAVH TRLDGIKVVV 190 200 210 220 230 240 DCAHGAAYQA APMAYEAAGA EVVAVSNKPN GYNINDGVGS THIDQLQKAV VEHGADLGLA 250 260 270 280 290 300 HDGDADRCLA VDAQGNVVDG DQIMAVLALS MKDGGELKRN TLVATVMSNL GLKLAMERNG 310 320 330 340 350 360 ITLRQTQVGD RYVVEDLRAG DYSLGGEQSG HIVIPEHGTT GDGLLTGLFL MARMATTGKT 370 380 390 400 410 420 LAELASAMQV LPQTLINVPV SNKAAIAGDA RVKQAIAKAE EELGETGRVL LRPSGTEELF 430 440 RVMVEAADSA TARKIAGQLA AVVAEV

References

[1]

"The lifestyle of Corynebacterium urealyticum derived from its complete genome sequence established by pyrosequencing." Tauch A., Trost E., Tilker A., Ludewig U., Schneiker S., Goesmann A., Arnold W., Bekel T., Brinkrolf K., Brune I., Goetker S., Kalinowski J., Kamp P.-B., Lobo F.P., Viehoever P., Weisshaar B., Soriano F., Droege M., Puehler A. J. Biotechnol. 136:11-21(2008) [PubMed: 18367281] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43042 / DSM 7109.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM942444 Genomic DNA. Translation: CAQ04338.1.
RefSeq	YP_001799772.1. NC_010545.1.
3D structure databases
ProteinModelPortal	B1VEZ9.
ModBase	Search...
Protein-protein interaction databases
STRING	B1VEZ9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6186043.
GenomeReviews	Gene locus cu0378 in contig AM942444_GR.
KEGG	cur:cur_0378.
PATRIC	21520468. VBICorUre58120_0377.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG644964.
OMA	GVGSTHL.
ProtClustDB	PRK14318.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_CORU7

Accession

Primary (citable) accession number: B1VEZ9

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	May 20, 2008
Last modified:	January 25, 2012
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program