Skip Header

Contribute Send feedback
Read comments (?) or add your own

B1VDM9 (B1VDM9_CORU7) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Dihydroorotase RuleBase RU003441
EC=3.5.2.3 RuleBase RU003441
Gene names
Ordered Locus Names:cu0967
OrganismCorynebacterium urealyticum (strain ATCC 43042 / DSM 7109) [Complete proteome] [HAMAP]
Taxonomic identifier504474 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length455 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-dihydroorotate + H2O = N-carbamoyl-L-aspartate. RuleBase RU003441 SAAS SAAS002195

Cofactor

Binds 2 zinc ions per subunit By similarity. RuleBase RU003441 SAAS SAAS002195

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3. RuleBase RU003441 SAAS SAAS002195

Subunit structure

Homodimer By similarity. SAAS SAAS002195

Sequence similarities

Belongs to the DHOase family. Type 2 subfamily. RuleBase RU003441

Sequences

Sequence LengthMass (Da)Tools
B1VDM9 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: 53653586E37DBEDF

FASTA45549,010
        10         20         30         40         50         60 
MVDNKNFPPT GPLAAHPAGA ENAVLLKGVL IYGEGEPQDV LLSDGVIAKI GADLSTEAPA 

        70         80         90        100        110        120 
EAEVLDLSGQ VLLPGLVDMH VHLREPGRED TETIASGSAA AAKGGFTAVF TMANTSPVMD 

       130        140        150        160        170        180 
DPAIAESVWY KGQNTNLCDV HPVGSISKGL EGKELTEFGM MADSDAKVRM FSDDGKCVDD 

       190        200        210        220        230        240 
PRLMRRAIEY SRGMDVLLAQ HCEEPRLTEG AVAHEGETAA RLGLRGWPRV AEESIVARDA 

       250        260        270        280        290        300 
LMARDYGGRI HICHASTEGT VELLRWAKGQ DIPLSAEVTP HHLILTDSRL ETFDGVNRVN 

       310        320        330        340        350        360 
PPLREERDTL ALRQALIDGV VDCVATDHAP HSSEEKCCEF DQARPGMLGL ETSLAIIADL 

       370        380        390        400        410        420 
FVINGDQDWR FVAKVMSERP AEITKLPGHG RPIAEGEPAN LCVVDTNASW TAEAKEMASK 

       430        440        450 
SENNPYEGMP MPVRVSTTIL RGKVTCRNGN PVKTD

« Hide

References

[1]"The lifestyle of Corynebacterium urealyticum derived from its complete genome sequence established by pyrosequencing."
Tauch A., Trost E., Tilker A., Ludewig U., Schneiker S., Goesmann A., Arnold W., Bekel T., Brinkrolf K., Brune I., Goetker S., Kalinowski J., Kamp P.-B., Lobo F.P., Viehoever P., Weisshaar B., Soriano F., Droege M., Puehler A.
J. Biotechnol. 136:11-21(2008) [PubMed: 18367281] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43042 / DSM 7109.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM942444 Genomic DNA. Translation: CAQ04927.1.
RefSeqYP_001800361.1. NC_010545.1.

3D structure databases

ProteinModelPortalB1VDM9.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1VDM9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6185321.
GenomeReviewsGene locus cu0967 in contig AM942444_GR.
KEGGcur:cur_0967.
PATRIC21521670. VBICorUre58120_0964.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG724623.
OMACDVHPVG.
ProtClustDBPRK09357.

Family and domain databases

HAMAPMF_00220_B. PyrC_type2_B.
[Tree]
InterProIPR006680. Amidohydro_1.
IPR004722. DHOase.
IPR002195. Dihydroorotase_CS.
IPR011059. Metal-dep_hydrolase_composite.
[Graphical view]
KOK01465.
PfamPF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMSSF51338. Metalo_hydrolase. 1 hit.
TIGRFAMsTIGR00857. PyrC_multi. 1 hit.
PROSITEPS00482. DIHYDROOROTASE_1. 1 hit.
PS00483. DIHYDROOROTASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB1VDM9_CORU7
AccessionPrimary (citable) accession number: B1VDM9
Entry history
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: January 25, 2012
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info