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B1VAN5

- PNP_PHYAS

UniProt

B1VAN5 - PNP_PHYAS

Protein

Polyribonucleotide nucleotidyltransferase

Gene

pnp

Organism
Phytoplasma australiense
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 45 (01 Oct 2014)
      Sequence version 1 (20 May 2008)
      Previous versions | rss
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    Functioni

    Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.UniRule annotation

    Catalytic activityi

    RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.UniRule annotation

    Cofactori

    Magnesium.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi501 – 5011MagnesiumUniRule annotation
    Metal bindingi507 – 5071MagnesiumUniRule annotation

    GO - Molecular functioni

    1. 3'-5'-exoribonuclease activity Source: InterPro
    2. magnesium ion binding Source: UniProtKB-HAMAP
    3. polyribonucleotide nucleotidyltransferase activity Source: UniProtKB-HAMAP
    4. RNA binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. mRNA catabolic process Source: UniProtKB-HAMAP
    2. RNA processing Source: InterPro

    Keywords - Molecular functioni

    Nucleotidyltransferase, Transferase

    Keywords - Ligandi

    Magnesium, Metal-binding, RNA-binding

    Enzyme and pathway databases

    BioCyciPAUS59748:GJ8P-684-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Polyribonucleotide nucleotidyltransferaseUniRule annotation (EC:2.7.7.8UniRule annotation)
    Alternative name(s):
    Polynucleotide phosphorylaseUniRule annotation
    Short name:
    PNPaseUniRule annotation
    Gene namesi
    Name:pnpUniRule annotation
    Ordered Locus Names:PA0674
    OrganismiPhytoplasma australiense
    Taxonomic identifieri59748 [NCBI]
    Taxonomic lineageiBacteriaTenericutesMollicutesAcholeplasmatalesAcholeplasmataceaeCandidatus Phytoplasma16SrXII (Stolbur group)
    ProteomesiUP000008323: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 710710Polyribonucleotide nucleotidyltransferasePRO_1000192481Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi59748.PAa_0674.

    Structurei

    3D structure databases

    ProteinModelPortaliB1VAN5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini568 – 62861KHUniRule annotationAdd
    BLAST
    Domaini638 – 71073S1 motifUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the polyribonucleotide nucleotidyltransferase family.UniRule annotation
    Contains 1 KH domain.UniRule annotation
    Contains 1 S1 motif domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1185.
    KOiK00962.
    OMAiGTENTIC.
    OrthoDBiEOG6WT8CC.

    Family and domain databases

    Gene3Di1.10.10.400. 1 hit.
    2.40.50.140. 1 hit.
    3.30.1370.10. 1 hit.
    3.30.230.70. 2 hits.
    HAMAPiMF_01595. PNPase.
    InterProiIPR001247. ExoRNase_PH_dom1.
    IPR015847. ExoRNase_PH_dom2.
    IPR004087. KH_dom.
    IPR004088. KH_dom_type_1.
    IPR012340. NA-bd_OB-fold.
    IPR012162. PNPase.
    IPR027408. PNPase/RNase_PH_dom.
    IPR015848. PNPase_PH_RNA-bd_bac/org-type.
    IPR003029. Rbsml_prot_S1_RNA-bd_dom.
    IPR020568. Ribosomal_S5_D2-typ_fold.
    IPR022967. RNA-binding_domain_S1.
    [Graphical view]
    PANTHERiPTHR11252. PTHR11252. 1 hit.
    PfamiPF00013. KH_1. 1 hit.
    PF01138. RNase_PH. 2 hits.
    PF03725. RNase_PH_C. 2 hits.
    [Graphical view]
    PIRSFiPIRSF005499. PNPase. 1 hit.
    SMARTiSM00322. KH. 1 hit.
    SM00316. S1. 1 hit.
    [Graphical view]
    SUPFAMiSSF46915. SSF46915. 1 hit.
    SSF50249. SSF50249. 1 hit.
    SSF54211. SSF54211. 2 hits.
    SSF54791. SSF54791. 1 hit.
    SSF55666. SSF55666. 2 hits.
    TIGRFAMsiTIGR03591. polynuc_phos. 1 hit.
    PROSITEiPS50084. KH_TYPE_1. 1 hit.
    PS50126. S1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B1VAN5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLKQVFETTD LKNSFQVEIG TYARNVDPSV LIRFQDTVVL TTTVFSNKKN    50
    NFDFLPLTVI YQEKFYAAGK IPGSFLRREG RSTDHEILSS RLIDRSLRPL 100
    FPKEFRQEIQ VINTVLSSNP DFKSEIASIL GSSLSLLISE IPFFEPVAGV 150
    YVAYIQNQFV INPNAQQLTN SPLHLLVAGT KKNVVMIEAH ASEVSEEMFL 200
    EAIVFAHEYI KKLCLFQEDV QKKVGQTKKL IDLDAELQSL EKEFNEQYHE 250
    QTRTLVANVF EQDQKNDLQV FKKKILAKAQ QKAFVKTIDQ ITFFDVEEQK 300
    NYLLLIENLF QKLFNQEMRN YIIKNKKRPD KRTLEEVRNL DSQIDLLPRP 350
    HGSALFTRGQ TQSLAVVTLG TLSESKIIDD LSGESNKRFM LHYNFPPFAV 400
    GSIGRYAAPS RREIGHGNLA EKAILPLLPE ENDFPYAIRV VSEILESNGS 450
    SSQATVCATS MSLMAAGVPL KRAVSGIAMG LFMDSKTNEY VILSDIQGLE 500
    DHIGDMDLKI AGSDKGITAL QMDLKIEGIS QAILKQAFFQ AKKGRLHILE 550
    HMNKTIASPR KEMSQYAPKV QMFQIKPEKI RDVIGSAGKI INQIIENHDG 600
    VKIDIEQDGR IFVMHSNLET VKQAILFIKN LIQDAEVNSI YHAHISRFLN 650
    DKAGNILGAF AQVSPSIEGL IRFSKAKKEN DVVKIGDKVL VKCVKINERG 700
    RIDFVLISKK 710
    Length:710
    Mass (Da):80,156
    Last modified:May 20, 2008 - v1
    Checksum:i12161A596AB8036E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM422018 Genomic DNA. Translation: CAM12008.1.
    RefSeqiWP_012359136.1. NC_010544.1.
    YP_001799249.1. NC_010544.1.

    Genome annotation databases

    EnsemblBacteriaiCAM12008; CAM12008; EBG00000298957.
    GeneIDi6799005.
    KEGGipal:PAa_0674.
    PATRICi31993750. VBICanPhy111091_0737.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM422018 Genomic DNA. Translation: CAM12008.1 .
    RefSeqi WP_012359136.1. NC_010544.1.
    YP_001799249.1. NC_010544.1.

    3D structure databases

    ProteinModelPortali B1VAN5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 59748.PAa_0674.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAM12008 ; CAM12008 ; EBG00000298957 .
    GeneIDi 6799005.
    KEGGi pal:PAa_0674.
    PATRICi 31993750. VBICanPhy111091_0737.

    Phylogenomic databases

    eggNOGi COG1185.
    KOi K00962.
    OMAi GTENTIC.
    OrthoDBi EOG6WT8CC.

    Enzyme and pathway databases

    BioCyci PAUS59748:GJ8P-684-MONOMER.

    Family and domain databases

    Gene3Di 1.10.10.400. 1 hit.
    2.40.50.140. 1 hit.
    3.30.1370.10. 1 hit.
    3.30.230.70. 2 hits.
    HAMAPi MF_01595. PNPase.
    InterProi IPR001247. ExoRNase_PH_dom1.
    IPR015847. ExoRNase_PH_dom2.
    IPR004087. KH_dom.
    IPR004088. KH_dom_type_1.
    IPR012340. NA-bd_OB-fold.
    IPR012162. PNPase.
    IPR027408. PNPase/RNase_PH_dom.
    IPR015848. PNPase_PH_RNA-bd_bac/org-type.
    IPR003029. Rbsml_prot_S1_RNA-bd_dom.
    IPR020568. Ribosomal_S5_D2-typ_fold.
    IPR022967. RNA-binding_domain_S1.
    [Graphical view ]
    PANTHERi PTHR11252. PTHR11252. 1 hit.
    Pfami PF00013. KH_1. 1 hit.
    PF01138. RNase_PH. 2 hits.
    PF03725. RNase_PH_C. 2 hits.
    [Graphical view ]
    PIRSFi PIRSF005499. PNPase. 1 hit.
    SMARTi SM00322. KH. 1 hit.
    SM00316. S1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46915. SSF46915. 1 hit.
    SSF50249. SSF50249. 1 hit.
    SSF54211. SSF54211. 2 hits.
    SSF54791. SSF54791. 1 hit.
    SSF55666. SSF55666. 2 hits.
    TIGRFAMsi TIGR03591. polynuc_phos. 1 hit.
    PROSITEi PS50084. KH_TYPE_1. 1 hit.
    PS50126. S1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Comparative genome analysis of 'Candidatus Phytoplasma australiense' (subgroup tuf-Australia I; rp-A) and 'Ca. Phytoplasma asteris' strains OY-M and AY-WB."
      Tran-Nguyen L.T., Kube M., Schneider B., Reinhardt R., Gibb K.S.
      J. Bacteriol. 190:3979-3991(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiPNP_PHYAS
    AccessioniPrimary (citable) accession number: B1VAN5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: May 20, 2008
    Last modified: October 1, 2014
    This is version 45 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3