B1P3E1 (B1P3E1_ACIBI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Diketoreductase EMBL ABY48099.1

Gene names

Name:

dkr EMBL ABY48099.1

Organism

Acinetobacter baylyi EMBL ABY48099.1

Taxonomic identifier

202950 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter

Protein attributes

Sequence length	283 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 4DYD PDB 4E12 PDB 4E13
Gene Ontology (GO)
Biological_process	fatty acid metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	3-hydroxyacyl-CoA dehydrogenase activity Inferred from electronic annotation. Source: InterPro NAD+ binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1P3E1 [UniParc]. Last modified April 29, 2008. Version 1. Checksum: 275E6E9E18FDD09A	FASTA	283	30,237
	10 20 30 40 50 60 MTGITNVTVL GTGVLGSQIA FQTAFHGFAV TAYDINTDAL DAAKKRFEGL AAVYEKEVAG 70 80 90 100 110 120 AADGAAQKAL GGIRYSDDLA QAVKDADLVI EAVPESLDLK RDIYTKLGEL APAKTIFATN 130 140 150 160 170 180 SSTLLPSDLV GYTGRGDKFL ALHFANHVWV NNTAEVMGTT KTDPEVYQQV VEFASAIGMV 190 200 210 220 230 240 PIELKKEKAG YVLNSLLVPL LDAAAELLVD GIADPETIDK TWRIGTGAPK GPFEIFDIVG 250 260 270 280 LTTAYNISSV SGPKQREFAA YLKENYIDKG KLGLATGEGF YRY

References

[1]	"Cloning, expression, and characterization of a novel diketoreductase from Acinetobacter baylyi." Wu X., Liu N., He Y., Chen Y. Acta Biochim. Biophys. Sin. 41:163-170(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: ATCC 33305 EMBL ABY48099.1.
[2]	"Dual catalysis mode for the dicarbonyl reduction catalyzed by diketoreductase." Lu M., Huang Y., White M.A., Wu X., Liu N., Cheng X., Chen Y. Chem. Commun. (Camb.) 48:11352-11354(2012) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.93 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

EU273886 Genomic DNA. Translation: ABY48099.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
4DYD	X-ray	1.95	A	1-283	[»]
4E12	X-ray	1.93	A	1-283	[»]
4E13	X-ray	2.08	A	1-283	[»]

ProteinModelPortal

B1P3E1.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

Gene3D

1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.

InterPro

IPR022694. 3-OHacyl-CoA_DH.
IPR006176. 3-OHacyl-CoA_DH_NAD-bd.
IPR006108. 3HC_DH_C.
IPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR016040. NAD(P)-bd_dom.
[Graphical view]

Pfam

PF00725. 3HCDH. 1 hit.
PF02737. 3HCDH_N. 1 hit.
[Graphical view]

PIRSF

PIRSF000105. HCDH. 1 hit.

SUPFAM

SSF48179. 6DGDH_C_like. 1 hit.

ProtoNet

Search...

Entry information

Entry name

B1P3E1_ACIBI

Accession

Primary (citable) accession number: B1P3E1

Entry history

Integrated into UniProtKB/TrEMBL:	April 29, 2008
Last sequence update:	April 29, 2008
Last modified:	March 6, 2013
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)