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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Leuconostoc citreum (strain KM20)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

  1. arginine-tRNA ligase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciLCIT349519:GHNF-1026-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:LCK_01007
OrganismiLeuconostoc citreum (strain KM20)
Taxonomic identifieri349519 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLeuconostocaceaeLeuconostoc
ProteomesiUP000002166: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 563563Arginine--tRNA ligasePRO_1000095378Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi349519.LCK_01007.

Structurei

3D structure databases

ProteinModelPortaliB1MZ82.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi121 – 13111"HIGH" regionAdd
BLAST

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0018.
HOGENOMiHOG000247211.
KOiK01887.
OMAiNPNGPLH.
OrthoDBiEOG6JB13C.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.

Sequencei

Sequence statusi: Complete.

B1MZ82-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDNKSIITS LSQVLPDIPV AEIAAKLESP KSSDLGDVAF PTFTLAKLLR
60 70 80 90 100
QAPQQIASDI VNRIDQSNFE KVVATGPYVN FFLDKKMTSQ ATLKTILTQG
110 120 130 140 150
AAFGDNNDGD GANVTIDMSS PNIAKPMSMG HLRSTVIGNA LANITAKNGY
160 170 180 190 200
HPIKINHLGD WGTQFGKLIY AYKTWGTEAE VKADPIATLL RYYVEFHEKA
210 220 230 240 250
KIDDSLNDAG RAWFKKLEDG DEEAHQLWTW FRAESLKEFT EIYDRLEISF
260 270 280 290 300
DSFNGEAFYN DKMDKVVDML AEKSLLVESQ GAQIVDLSDI NPNLTPAMIK
310 320 330 340 350
RTDGATLYMT RDLAAAVYRK ETYNFAKSLY VVGGEQREHF VQMKAVLSLM
360 370 380 390 400
GFDWADDVEH IAFGLITFNG KKMSTRKGDV VLLKDVLNDA HDLALKQIQE
410 420 430 440 450
KNPDLADKAT VAEQVGAGAV VFHDLMNDRT NNFDFNLEEV VRFEGDTGPY
460 470 480 490 500
VQYTNARAKS ILRKANTAVS VDELNLDDTA TWDIITTLNQ FPTIVQRAWQ
510 520 530 540 550
QREASIIAKY ALSLSRAFNK YYANSKILLP DDQLNARLAL VKAVTIILSE
560
SLRLLGVKAP EEM
Length:563
Mass (Da):62,783
Last modified:April 29, 2008 - v1
Checksum:i17D5C526A02A5EBC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ489736 Genomic DNA. Translation: ACA82834.1.
RefSeqiYP_001728278.1. NC_010471.1.

Genome annotation databases

EnsemblBacteriaiACA82834; ACA82834; LCK_01007.
GeneIDi6063775.
KEGGilci:LCK_01007.
PATRICi32615304. VBILeuCit37309_1132.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ489736 Genomic DNA. Translation: ACA82834.1.
RefSeqiYP_001728278.1. NC_010471.1.

3D structure databases

ProteinModelPortaliB1MZ82.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi349519.LCK_01007.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACA82834; ACA82834; LCK_01007.
GeneIDi6063775.
KEGGilci:LCK_01007.
PATRICi32615304. VBILeuCit37309_1132.

Phylogenomic databases

eggNOGiCOG0018.
HOGENOMiHOG000247211.
KOiK01887.
OMAiNPNGPLH.
OrthoDBiEOG6JB13C.

Enzyme and pathway databases

BioCyciLCIT349519:GHNF-1026-MONOMER.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KM20.

Entry informationi

Entry nameiSYR_LEUCK
AccessioniPrimary (citable) accession number: B1MZ82
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: April 29, 2008
Last modified: March 4, 2015
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.