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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Leuconostoc citreum (strain KM20)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei140GTPUniRule annotation1
Binding sitei144GTPUniRule annotation1
Binding sitei188GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi22 – 26GTPUniRule annotation5
Nucleotide bindingi109 – 111GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotationImported
Ordered Locus Names:LCK_00532Imported
OrganismiLeuconostoc citreum (strain KM20)Imported
Taxonomic identifieri349519 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLeuconostocaceaeLeuconostoc
Proteomesi
  • UP000002166 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation
  • Note: Assembles at midcell at the inner surface of the cytoplasmic membrane.UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.UniRule annotation

Protein-protein interaction databases

STRINGi349519.LCK_00532.

Structurei

3D structure databases

ProteinModelPortaliB1MXW3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 206TubulinInterPro annotationAdd BLAST193
Domaini208 – 325Tubulin_CInterPro annotationAdd BLAST118

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDK. Bacteria.
COG0206. LUCA.
HOGENOMiHOG000049094.
KOiK03531.
OMAiMRAVKGI.

Family and domain databases

CDDicd02201. FtsZ_type1. 1 hit.
Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ. 1 hit.
InterProiView protein in InterPro
IPR000158. Cell_div_FtsZ.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR037103. Tubulin/FtsZ_C_sf.
IPR036525. Tubulin/FtsZ_GTPase_sf.
IPR003008. Tubulin_FtsZ_GTPase.
PfamiView protein in Pfam
PF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiView protein in SMART
SM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
PROSITEiView protein in PROSITE
PS01134. FTSZ_1. 1 hit.

Sequencei

Sequence statusi: Complete.

B1MXW3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDFSIDDAQQ AGAIIKVIGV GGGGSNAVNH MIEEGVNGVE FIVANTDVQA
60 70 80 90 100
LDKSKADVKI QIGPKLTGGL GAGSNPERGT KAAEESAEDI ASALSGADMV
110 120 130 140 150
VITAGMGGGT GNGAAPVVAR IAKEQGALTV AVVTRPFKWE GPKRGRFAAE
160 170 180 190 200
GLQALSESVD SLIVITNERL KDRIDLRTPL SEAFKVVDEV VAQGVRGISE
210 220 230 240 250
LITNPGFINL DFADVKTVMQ DAGPALMGVG QASGETRAAD ATKQAISSPL
260 270 280 290 300
LEVDMSGAED VLLNITGGLD MSLFEAQTAS EVIAQEAGRE VNVIFGTSID
310 320 330 340 350
ENLEDSIRVT VIATGLQNIT NDGTQKKGAN PKANAASVFG NAANTDNKTS
360 370 380 390 400
TSAPQSSVFE KPATEQTSQP VQPTQKDPFA DWNISGASKD AFAEDNRFDG
410 420 430
VQKQSFDVFN TPTSNTSSVD FSSTDDENEQ PPFFKKR
Length:437
Mass (Da):45,583
Last modified:April 29, 2008 - v1
Checksum:i04D403B2817C090D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ489736 Genomic DNA. Translation: ACA82365.1.
RefSeqiWP_004908075.1. NC_010471.1.

Genome annotation databases

EnsemblBacteriaiACA82365; ACA82365; LCK_00532.
KEGGilci:LCK_00532.

Similar proteinsi

Entry informationi

Entry nameiB1MXW3_LEUCK
AccessioniPrimary (citable) accession number: B1MXW3
Entry historyiIntegrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: October 25, 2017
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported