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B1MMY6 (B1MMY6_MYCA9) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutamate 5-kinase HAMAP MF_00456
EC=2.7.2.11 HAMAP MF_00456
Alternative name(s):
Gamma-glutamyl kinase HAMAP MF_00456
Gene names
Name:proB HAMAP MF_00456
Ordered Locus Names:MAB_1613
OrganismMycobacterium abscessus (strain ATCC 19977 / DSM 44196) [Complete proteome] [HAMAP]
Taxonomic identifier561007 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium abscessus

Protein attributes

Sequence length368 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5-oxoproline By similarity. HAMAP MF_00456 SAAS SAAS011529

Catalytic activity

ATP + L-glutamate = ADP + L-glutamate 5-phosphate. HAMAP MF_00456 SAAS SAAS011529

Pathway

Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2. HAMAP MF_00456 SAAS SAAS011529

Subcellular location

Cytoplasm By similarity SAAS SAAS011529 HAMAP MF_00456.

Sequence similarities

Belongs to the glutamate 5-kinase family. HAMAP MF_00456

Contains 1 PUA domain. HAMAP MF_00456 SAAS SAAS011529

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain281 – 35979PUA By similarity HAMAP MF_00456

Sequences

Sequence LengthMass (Da)Tools
B1MMY6 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: D84418A2E190CB1F

FASTA36838,039
        10         20         30         40         50         60 
MNPGAQAREA IRSARTVVVK VGTAALTDET GTFSADRMEY LVEVIEGRMK AGSDVVIVSS 

        70         80         90        100        110        120 
GAIAAGMVPL GLTKRPTDLA TKQAAASAGQ VALIGAWSAA FARYERTVGQ VLLTAHDISM 

       130        140        150        160        170        180 
RVHHTNAQRT LDRLTALHAV AIVNENDTVA TNEIRFGDND RLSALVAHLV GADALVLLSD 

       190        200        210        220        230        240 
IDGLYDSDPR KGNARFISEV SGPEDLADVI AGPGGSRGTG GMASKLSSAL LASDAGVPVL 

       250        260        270        280        290        300 
LASATEAAAA LGDGSCGTVF AARPQRMSAR KFWVRYAAEA TGSLTLDAGA VRAVVASRRS 

       310        320        330        340        350        360 
LLPAGITGVS GRFHGGDVVE LRDADGTMVG RGVVAYDVAE LATMLGRSTN ELPEDLRRPA 


VHADDLVT

« Hide

References

[1]"Acquisition of foreign virulence genes by the cystic fibrosis pathogen Mycobacterium abscessus."
Genoscope
Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L., Gaillard J.L.
Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CU458896 Genomic DNA. Translation: CAM61698.1.
RefSeqYP_001702352.1. NC_010397.1.

3D structure databases

ProteinModelPortalB1MMY6.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1MMY6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000006487; EBMYCP00000006426; EBMYCG00000006485.
GeneID5964131.
GenomeReviewsGene locus MAB_1613 in contig CU458896_GR.
KEGGmab:MAB_1613.
PATRIC17974937. VBIMycAbs55940_1653.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000017499.
HOGENOMHBG507643.
OMATFGDNDM.
ProtClustDBPRK05429.

Family and domain databases

HAMAPMF_00456. ProB.
[Tree]
InterProIPR001048. Asp/Glu/Uridylate_kinase.
IPR001057. Glu/AcGlu_kinase.
IPR011529. Glu_5kinase.
IPR005715. Glu_5kinase/COase_Synthase.
IPR019797. Glutamate_5-kinase_CS.
IPR002478. PUA.
IPR015947. PUA-like_domain.
[Graphical view]
Gene3DG3DSA:3.40.1160.10. Aa_kinase. 1 hit.
KOK00931.
PfamPF00696. AA_kinase. 1 hit.
PF01472. PUA. 1 hit.
[Graphical view]
PIRSFPIRSF000729. GK. 1 hit.
PRINTSPR00474. GLU5KINASE.
SMARTSM00359. PUA. 1 hit.
[Graphical view]
SUPFAMSSF53633. Aa_kinase. 1 hit.
SSF88697. PUA-like. 1 hit.
TIGRFAMsTIGR01027. ProB. 1 hit.
PROSITEPS00902. GLUTAMATE_5_KINASE. 1 hit.
PS50890. PUA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB1MMY6_MYCA9
AccessionPrimary (citable) accession number: B1MMY6
Entry history
Integrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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