B1MLQ2 (B1MLQ2_MYCA9) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Probable 2-oxoglutarate dehydrogenase SucA EMBL CAM61479.1

Gene names

Ordered Locus Names:

MAB_1393c

Organism

Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) [Complete proteome] [HAMAP]

Taxonomic identifier

561007 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium abscessus

Protein attributes

Sequence length	1238 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the 2-oxoacid dehydrogenase family. RuleBase RU003423

Ontologies

Keywords
Ligand	Thiamine pyrophosphate SAAS SAAS001017
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular function	oxoglutarate dehydrogenase (succinyl-transferring) activity Inferred from electronic annotation. Source: InterPro thiamine pyrophosphate binding Inferred from electronic annotation. Source: InterPro transferase activity, transferring acyl groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1MLQ2 [UniParc]. Last modified April 29, 2008. Version 1. Checksum: B62A53614F445EDF	FASTA	1,238	135,969
	10 20 30 40 50 60 MNGSNPQFGQ NEWLVEEMYR RFKEDPSSVD SSWHEFLSDF GAESVAEPAT ASANGHAAPA 70 80 90 100 110 120 PAPTPAAPAP APAPAAAPAP APAVKPASAP STAPAAPKPA APPIPTAEGD EAQVLRGAAA 130 140 150 160 170 180 AVVKNMSASL EIPTATSVRA IPAKLMIDNR IVINNHLKRT RGGKISFTHL LGYAIVQAIK 190 200 210 220 230 240 DFPNMNRHFA EVDGKPVAIT PAHVNLGLAI DLPGKDGNRT LVVAAIKGCE ALGFGQFIAA 250 260 270 280 290 300 YEDIVRRARD GKLTAEDFSG VTISLTNPGT IGTVHSVPRL MRGQGAIIGA GALEYPAEFQ 310 320 330 340 350 360 GASEERIADL GIGKHMTLTS TYDHRIIQGA ESGDFLRTVH QLLLSDDFFD DIFRELGIPY 370 380 390 400 410 420 EPVRWRIDNP DSIVDKNARV LELIAAYRNR GHLMADTDPL RLDKTRFRSH PDLDVLSHGL 430 440 450 460 470 480 TLWDLDREFK VSGFKGQEYM KLRDVLSVLR DAYCRHAGVE YTHILEPEQQ KWLQERIEAK 490 500 510 520 530 540 HDKPTVAEQK YILSKLNAAE AFETFLATKY VGQKRFSLEG AEGVIPMMDA VIDQSAEHGL 550 560 570 580 590 600 DEVVIGMPHR GRLNVLANIV GKPYSQIFTE FEGNLNPALA HGSGDVKYHL GASGTYIQMF 610 620 630 640 650 660 GDNDIEVSLT ANPSHLEAVD PVLEGLVRAK QDLLDVGTDG GRFTVVPLML HGDAAFAGQG 670 680 690 700 710 720 VVAETLNLAN LPGYRTGGTI HIVVNNQIGF TTAPEHSRST EYCTDIAKMI GAPIFHVNGD 730 740 750 760 770 780 DPEACVWVSR LAVDFRQKFN KDVVIDLVCY RRRGHNEGDD PSMTNPQMYE VIDTKRGVRK 790 800 810 820 830 840 TYTEALIGRG DISMKEAEDA LRDYQGQLER VFNEVRDLEK YQQRPSESVE EDQQLPQKLV 850 860 870 880 890 900 TAVDKALLQR IGDAFLSVPE DFSVHPRVKP VLDKRREMAY EGKVDWAFGE LLAFGTLVAE 910 920 930 940 950 960 GKVVRLSGQD SKRGTFTQRH AVIIDRHNGT EFSPLQLVGV DAEGNPTGGR LVVHDSALSE 970 980 990 1000 1010 1020 YAALGFEYGY SVGNPDAMVL WEAQFGDFVN GAQSIIDEFI SSGEAKWGQL SEVVLLLPHG 1030 1040 1050 1060 1070 1080 HEGQGPDHTS GRIERFLQLC AEGSMTVAMP STPANYFHLL RRHALDGITR PMVVFTPKSM 1090 1100 1110 1120 1130 1140 LRNKAAVSDI KDFTDRKFRS VLEEPTYEDG VGDRSKVKRI LLTSGKLYYD LLARKNSDKR 1150 1160 1170 1180 1190 1200 DDVAIVRIEQ LYPIPRYRLE ETLSRYPDDA QYIWVQEEPA NQGAWPTFGL NLPEVVPRLT 1210 1220 1230 GLTKISRRAM SAPSSGSSKV HAVEQQEIID EAFAPTSG

References

[1]

"Acquisition of foreign virulence genes by the cystic fibrosis pathogen Mycobacterium abscessus." Genoscope Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L., Gaillard J.L. Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU458896 Genomic DNA. Translation: CAM61479.1.
RefSeq	YP_001702133.1. NC_010397.1.
3D structure databases
ProteinModelPortal	B1MLQ2.
ModBase	Search...
Protein-protein interaction databases
STRING	B1MLQ2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000007296; EBMYCP00000007235; EBMYCG00000007294.
GeneID	5963915.
GenomeReviews	Gene locus MAB_1393c in contig CU458896_GR.
KEGG	mab:MAB_1393c.
PATRIC	17974475. VBIMycAbs55940_1432.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000014858.
HOGENOM	HBG289950.
OMA	EGDEPAF.
ProtClustDB	PRK12270.
Family and domain databases
InterPro	IPR001078. 2-oxoacid_DH_actylTfrase. IPR011603. 2oxoglutarate_DH_E1. IPR023213. CAT-like_dom. IPR001017. DH_E1. IPR005475. Transketolase-like_Pyr-bd. [Graphical view]
Gene3D	G3DSA:3.30.559.10. CAT-like_dom. 1 hit.
KO	K01616.
PANTHER	PTHR23152. 2oxoglutarate_DH_E1. 1 hit.
Pfam	PF00198. 2-oxoacid_dh. 1 hit. PF00676. E1_dh. 1 hit. PF02779. Transket_pyr. 1 hit. [Graphical view]
PIRSF	PIRSF000157. Oxoglu_dh_E1. 1 hit.
SMART	SM00861. Transket_pyr. 1 hit. [Graphical view]
TIGRFAMs	TIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B1MLQ2_MYCA9

Accession

Primary (citable) accession number: B1MLQ2

Entry history

Integrated into UniProtKB/TrEMBL:	April 29, 2008
Last sequence update:	April 29, 2008
Last modified:	December 14, 2011
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)