B1MLJ1 (B1MLJ1_MYCA9) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Probable pyrroline-5-carboxylate dehydrogenase RocA (Aldehyde dehydrogenase family) EMBL CAM61418.1

Gene names

Ordered Locus Names:

MAB_1330

Organism

Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) [Complete proteome] [HAMAP]

Taxonomic identifier

561007 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium abscessus

Protein attributes

Sequence length	544 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the aldehyde dehydrogenase family. RuleBase RU003345

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU003344
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proline biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	mitochondrial matrix Inferred from electronic annotation. Source: InterPro
Molecular function	1-pyrroline-5-carboxylate dehydrogenase activity Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1MLJ1 [UniParc]. Last modified April 29, 2008. Version 1. Checksum: 8B635A2095103486	FASTA	544	58,681
	10 20 30 40 50 60 MDAITTVPAP SNEPVLTYAP NTPERDRLTT ALGELTASPI DLPHVIGGAR RMSDGERIDV 70 80 90 100 110 120 VQPHNHRSVL GTVTNAGHRE AHDAVEAAIA AKNYWATLPF DDRAAVFLRA ADLLSGPWRA 130 140 150 160 170 180 ILNAATMLGQ SKTAYQAEID SACELADFWR FNVQFARQIL AEQPNSGGGA WNRLEYRPLE 190 200 210 220 230 240 GFVYAITPFN FTAIAGNLPT APALLGNTVV WKPSVTQAFA AHFTLELLEA AGLPPGVINL 250 260 270 280 290 300 LNGDGIAVSD VALADPRLAG IHFTGSTRTF QHLWRQVGTN IDRYNTYPRL VGETGGKDFV 310 320 330 340 350 360 VAHASARPEI LRTALIRGAF DYQGQKCSAA SRAFVPRSVW DQMGDEFLDA TSGLSYGDVT 370 380 390 400 410 420 DLSNFGGAVI DEKSFARNAA AIDRAKSAGV TIAAGGEYDD SQGYFVRPTV LLSDDPTDEA 430 440 450 460 470 480 FSTEYFGPIL AVHVYPDDDY GRILDVVDTG SPYGLTGAVI ADDRAAIRQA SDRLRYAAGN 490 500 510 520 530 540 FYVNDKPTGA VVGQQPFGGG RASGTDDKAG SPLNLQRWLL PRSIKETFNA PTEYQYPHME REDG

References

[1]

"Acquisition of foreign virulence genes by the cystic fibrosis pathogen Mycobacterium abscessus." Genoscope Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L., Gaillard J.L. Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU458896 Genomic DNA. Translation: CAM61418.1.
RefSeq	YP_001702072.1. NC_010397.1.
3D structure databases
ProteinModelPortal	B1MLJ1.
ModBase	Search...
Protein-protein interaction databases
STRING	B1MLJ1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000004768; EBMYCP00000004707; EBMYCG00000004766.
GeneID	5963854.
GenomeReviews	Gene locus MAB_1330 in contig CU458896_GR.
KEGG	mab:MAB_1330.
PATRIC	17974347. VBIMycAbs55940_1368.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000015660.
HOGENOM	HBG752218.
OMA	CELVDFW.
ProtClustDB	CLSK871904.
Family and domain databases
InterPro	IPR016161. Ald_DH/histidinol_DH. IPR016163. Ald_DH_C. IPR016160. Ald_DH_CS. IPR016162. Ald_DH_N. IPR015590. Aldehyde_DH_dom. IPR005931. Delta1-pyrroline-5-COlate_DH-1. [Graphical view]
Gene3D	G3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit. G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KO	K00294.
Pfam	PF00171. Aldedh. 1 hit. [Graphical view]
SUPFAM	SSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMs	TIGR01236. D1pyr5carbox1. 1 hit.
PROSITE	PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B1MLJ1_MYCA9

Accession

Primary (citable) accession number: B1MLJ1

Entry history

Integrated into UniProtKB/TrEMBL:	April 29, 2008
Last sequence update:	April 29, 2008
Last modified:	December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)