B1ML11 (Y4587_MYCA9) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative S-adenosyl-L-methionine-dependent methyltransferase MAB_4587c
EC=2.1.1.-

Gene names

Ordered Locus Names:

MAB_4587c

Organism

Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) [Complete proteome] [HAMAP]

Taxonomic identifier

561007 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium chelonae group › Mycobacterium abscessus subgroup › Mycobacterium abscessus

Protein attributes

Sequence length	310 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity By similarity.
Sequence similarities	Belongs to the UPF0677 family.

Ontologies

Keywords
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular_function	methyltransferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 310	310	Putative S-adenosyl-L-methionine-dependent methyltransferase MAB_4587c		PRO_0000361127
Regions
	Region	155 – 156	2	S-adenosyl-L-methionine binding By similarity
Sites
	Binding site	126	1	S-adenosyl-L-methionine By similarity

Sequences

	Sequence		Length	Mass (Da)
	B1ML11 [UniParc]. Last modified April 29, 2008. Version 1. Checksum: FCCBC748BFB3F994	FASTA	310	33,830
	10 20 30 40 50 60 MARTEGDTWD IVTSVGATAL VVSAMRAIEA RKPEPLARDD YAQHFVAATK AEAPLFSELL 70 80 90 100 110 120 EDPEAAQAPD IQLFSSYLGA RTKYFDEFFL TAGNAGVRQA VILAAGLDVR GYRLPWAAGT 130 140 150 160 170 180 TVYELDLPKV LEFKKQVLDE HNARATATVL DLHVDLRDDW PTVLKAAGFD PAQPTAWLAE 190 200 210 220 230 240 GLLPFLPGAA QDLLFERIAD LSAPGSRVAV EDFGAPGNQA DRMSNAMQNE EGALQRIFKS 250 260 270 280 290 300 IVEEDAPPSS LWFGDEREDP ARWLTGHGWT VEATTAGELL KRYNRVPLAG EHELTDAMGQ 310 SRYFTAVLGA

References

[1]

"Acquisition of foreign virulence genes by the cystic fibrosis pathogen Mycobacterium abscessus." Genoscope Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L., Gaillard J.L. Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 19977 / DSM 44196.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU458896 Genomic DNA. Translation: CAM64656.1.
RefSeq	YP_001705310.1. NC_010397.1.
3D structure databases
ProteinModelPortal	B1ML11.
ModBase	Search...
Protein-protein interaction databases
STRING	561007.MAB_4587c.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAM64656; CAM64656; MAB_4587c.
GeneID	5967045.
KEGG	mab:MAB_4587c.
PATRIC	17980994. VBIMycAbs55940_4661.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3315.
HOGENOM	HOG000240238.
OMA	RCERITV.
Enzyme and pathway databases
BioCyc	MABS561007:GJTG-4603-MONOMER.
Family and domain databases
InterPro	IPR011610. CHP00027_methylltransferase. IPR007213. LCM_MeTrfase. [Graphical view]
Pfam	PF04072. LCM. 1 hit. [Graphical view]
TIGRFAMs	TIGR00027. mthyl_TIGR00027. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Y4587_MYCA9

Accession

Primary (citable) accession number: B1ML11

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 20, 2009
Last sequence update:	April 29, 2008
Last modified:	May 1, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program