Skip Header

Contribute Send feedback
Read comments (?) or add your own

B1MJT6 (B1MJT6_MYCA9) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase HAMAP MF_01653
EC=1.13.11.16 HAMAP MF_01653
Gene names
Name:mhpB HAMAP MF_01653
Ordered Locus Names:MAB_4372
OrganismMycobacterium abscessus (strain ATCC 19977 / DSM 44196) [Complete proteome] [HAMAP]
Taxonomic identifier561007 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium abscessus

Protein attributes

Sequence length317 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6-ketononatrienedioate, respectively By similarity. HAMAP MF_01653

Catalytic activity

(2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate + O2 = 2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioate. HAMAP MF_01653

3-(2,3-dihydroxyphenyl)propanoate + O2 = 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate. HAMAP MF_01653

Cofactor

Fe2+ ion By similarity. HAMAP MF_01653

Pathway

Aromatic compound metabolism; 3-phenylpropanoate degradation. HAMAP MF_01653

Subunit structure

Homotetramer By similarity. HAMAP MF_01653

Sequence similarities

Belongs to the ligB/mhpB extradiol dioxygenase family. HAMAP MF_01653

Sequences

Sequence LengthMass (Da)Tools
B1MJT6 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: BA1E69F24F5B68A0

FASTA31733,837
        10         20         30         40         50         60 
MLMTCALVGL SHSPLVGKND PASDTLARIN SAIEHARSFV HEFRPELVVL YAPDHYNGFF 

        70         80         90        100        110        120 
YKEMPPFCLA TEAHAVGDFG SPAGQLSVDS DAAQLLARGV LSRNVDLTVS ARMTVDHGFT 

       130        140        150        160        170        180 
QPLEMLFGGI DRVPMVPIFI NGVAGPFGPL NRIRALGTAL GHEAAALGRR VLFLASGGLS 

       190        200        210        220        230        240 
HDPPVPVLQG APPRVADALI EGHPPSPEQR ARGEERVLAA GREYAAGSSS RIPINPIWDN 

       250        260        270        280        290        300 
EVLDTFESGD LEAIDSWTPE WMGSEGGGSA HEVRTWVAAY SSLAASGPYQ MLTRFYAAVP 

       310 
EWIAGFAVST AMRQVGP

« Hide

References

[1]"Acquisition of foreign virulence genes by the cystic fibrosis pathogen Mycobacterium abscessus."
Genoscope
Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L., Gaillard J.L.
Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CU458896 Genomic DNA. Translation: CAM64443.1.
RefSeqYP_001705097.1. NC_010397.1.

3D structure databases

ProteinModelPortalB1MJT6.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1MJT6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000006604; EBMYCP00000006543; EBMYCG00000006602.
GeneID5966832.
GenomeReviewsGene locus MAB_4372 in contig CU458896_GR.
KEGGmab:MAB_4372.
PATRIC17980572. VBIMycAbs55940_4450.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000017557.
HOGENOMHBG565586.
OMAAHEIRTW.
ProtClustDBPRK13370.

Family and domain databases

HAMAPMF_01653. MhpB.
[Tree]
InterProIPR023789. DHPP/DHXA_dioxygenase.
IPR004183. Xdiol_dOase_suB.
[Graphical view]
Gene3DG3DSA:3.40.830.10. Xdiol_dOase_3B. 2 hits.
KOK05713.
PfamPF02900. LigB. 1 hit.
[Graphical view]
SUPFAMSSF53213. Xdiol_dOase_3B. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB1MJT6_MYCA9
AccessionPrimary (citable) accession number: B1MJT6
Entry history
Integrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: January 25, 2012
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info