B1MIS8 (B1MIS8_MYCA9) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphate acetyltransferase PIRNR PIRNR006107
EC=2.3.1.8 PIRNR PIRNR006107

Alternative name(s):
Phosphotransacetylase PIRNR PIRNR006107

Gene names

Ordered Locus Names:

MAB_4226c

Organism

Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) [Complete proteome] [HAMAP]

Taxonomic identifier

561007 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium abscessus

Protein attributes

Sequence length	693 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in acetate metabolism By similarity. PIRNR PIRNR006107
Catalytic activity	Acetyl-CoA + phosphate = CoA + acetyl phosphate. PIRNR PIRNR006107
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2. PIRNR PIRNR006107
Subcellular location	Cytoplasm By similarity PIRNR PIRNR006107.
Domain	The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site By similarity. PIRNR PIRNR006107
Sequence similarities	In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family. PIRNR PIRNR006107 In the N-terminal section; belongs to the CobB/CobQ family. PIRNR PIRNR006107

Ontologies

Keywords
Cellular component	Cytoplasm PIRNR PIRNR006107
Molecular function	Acyltransferase PIRNR PIRNR006107 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	phosphate acetyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1MIS8 [UniParc]. Last modified April 29, 2008. Version 1. Checksum: AF5C78860D57B5C8	FASTA	693	73,911
	10 20 30 40 50 60 MTQPKASSIY IASPEGDTGK STVALGVMHR LAASVARVGV FRPIARSGES VDYILELLLE 70 80 90 100 110 120 QSTADIAYED CLGVSYHDVH QDPDAAIAQI VDRYHAVAER CDAVVIVGSD YTDVASPSEL 130 140 150 160 170 180 GTNARIAVNL GAPVLLTIKG FDRTPDEVAA LAEVCLGELK AQRAHTAAIV ANRCNPGQLD 190 200 210 220 230 240 EVRQALARFD KPAWVLPEVP LLVSPSVEEL MKAVKGSLVS GDEALLSREA TSFMVAGMTA 250 260 270 280 290 300 EHCLERLKEG QAVIFPADRS DVLLAVASAH VAEGFPSLSA IILNGGLKLH PRIADLVDGI 310 320 330 340 350 360 GLRLPIIETD SGTFETASAA AHARGRVTVA SARKIDTALA LMDRYVDGAD LVAQLAIPIP 370 380 390 400 410 420 SVTTPQMFEY QLLDRARDNR KRIVLPEGDD DRILKAAGRL LQRQVADLTI LGEEAEIRSR 430 440 450 460 470 480 AAELGVDISN ALVVSPKTSD LAEKFADQYF ELRKHKGMTP DRAREIMRNV SYFGTMLVYN 490 500 510 520 530 540 DIVDGMVSGA AHTTAHTIRP AFEVIRTTSG VSTVSSIFLM CLADRVLAYG DCAIVPDPTS 550 560 570 580 590 600 EQLADIAISS ARTAAQFGID PRVAMLSYST GSSGSGADVE KVRIATELVR SRQPELLVEG 610 620 630 640 650 660 PIQYDAAVEP SVAATKMPDS PVAGRATVLI FPDLNTGNNT YKAVQRSAGA VAIGPVLQGL 670 680 690 RKPINDLSRG ALVEDIVNTV AITAIQAQER KQS

References

[1]

"Acquisition of foreign virulence genes by the cystic fibrosis pathogen Mycobacterium abscessus." Genoscope Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L., Gaillard J.L. Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU458896 Genomic DNA. Translation: CAM64299.1.
RefSeq	YP_001704953.1. NC_010397.1.
3D structure databases
ProteinModelPortal	B1MIS8.
ModBase	Search...
Protein-protein interaction databases
STRING	B1MIS8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000004714; EBMYCP00000004653; EBMYCG00000004712.
GeneID	5966688.
GenomeReviews	Gene locus MAB_4226c in contig CU458896_GR.
KEGG	mab:MAB_4226c.
PATRIC	17980280. VBIMycAbs55940_4305.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000017507.
HOGENOM	HBG576804.
OMA	VTPLMFE.
ProtClustDB	PRK05632.
Family and domain databases
InterPro	IPR010766. DRTGG. IPR016475. P-Actrans_bac. IPR004614. P_AcTrfase. IPR002505. PTA_PTB. [Graphical view]
KO	K13788.
Pfam	PF07085. DRTGG. 1 hit. PF01515. PTA_PTB. 1 hit. [Graphical view]
PIRSF	PIRSF006107. PhpActrans_proteobac. 1 hit.
TIGRFAMs	TIGR00651. Pta. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B1MIS8_MYCA9

Accession

Primary (citable) accession number: B1MIS8

Entry history

Integrated into UniProtKB/TrEMBL:	April 29, 2008
Last sequence update:	April 29, 2008
Last modified:	December 14, 2011
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)