B1MIQ9 (B1MIQ9_MYCA9) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
4-aminobutyrate aminotransferase (GabT) EMBL CAM64280.1

Gene names

Ordered Locus Names:

MAB_4207 EMBL CAM64280.1

Organism

Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) [Complete proteome] [HAMAP]

Taxonomic identifier

561007 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium chelonae group › Mycobacterium abscessus subgroup › Mycobacterium abscessus

Protein attributes

Sequence length	449 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. RuleBase RU003560

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU003560
Molecular function	Aminotransferase EMBL CAM64280.1 Transferase
Technical term	3D-structure PDB 4FFC Complete proteome
Gene Ontology (GO)
Biological_process	gamma-aminobutyric acid metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	4-aminobutyrate transaminase activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1MIQ9 [UniParc]. Last modified April 29, 2008. Version 1. Checksum: 83EC8057A80BF883	FASTA	449	46,413
	10 20 30 40 50 60 MTDITYRLAQ KRTIVTPLPG PRSGALAERR RAAVSAGVGS TAPVYAVDAD GGVIVDADGN 70 80 90 100 110 120 SFIDLGAGIA VTTVGASHPA VAAAIADQAT HFTHTCFMVT PYEGYVQVAE LLNALTPGDH 130 140 150 160 170 180 DKRTALFNSG AEAVENAIKV ARLATGRPAV VAFDNAYHGR TNLTMALTAK SMPYKSQFGP 190 200 210 220 230 240 FAPEVYRMPA SYPLRDEPGL TGEEAARRAI SRIETQIGAQ SLAAIIIEPI QGEGGFIVPA 250 260 270 280 290 300 PGFLATLTAW ASENGVVFIA DEVQTGFART GAWFASEHEG IVPDIVTMAK GIAGGMPLSA 310 320 330 340 350 360 VTGRAELMDA VYAGGLGGTY GGNPVTCAAA VAALGVMREL DLPARARAIE ASVTSRLSAL 370 380 390 400 410 420 AEEVDIIGEV RGRGAMLAIE IVKPGTLEPD AALTKSIAAE ALSQGVLILT CGTFGNVIRL 430 440 LPPLVIGDDL LDEGITALSD IIRAKASHQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Acquisition of foreign virulence genes by the cystic fibrosis pathogen Mycobacterium abscessus." Genoscope Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L., Gaillard J.L. Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 19977 / DSM 44196.
[2]	"Crystal structure of a 4-aminobutyrate aminotransferase (GabT) from Mycobacterium abscessus." Seattle Structural Genomics Center for Infectious Disease (SSGCID) Edwards T.E., Fox III D., Abendroth J. Submitted (MAY-2012) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

CU458896 Genomic DNA. Translation: CAM64280.1.

RefSeq

YP_001704934.1. NC_010397.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
4FFC	X-ray	1.80	A/B/C/D	1-449	[»]

ProteinModelPortal

B1MIQ9.

ModBase

Search...

Protein-protein interaction databases

STRING

561007.MAB_4207.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

CAM64280; CAM64280; MAB_4207.

GeneID

5966669.

KEGG

mab:MAB_4207.

PATRIC

17980240. VBIMycAbs55940_4285.

Organism-specific databases

CMR

Search...

Phylogenomic databases

eggNOG

COG0160.

HOGENOM

HOG000020206.

KO

K07250.

OMA

DTREPDK.

ProtClustDB

PRK06058.

Enzyme and pathway databases

BioCyc

MABS561007:GJTG-4226-MONOMER.

Family and domain databases

Gene3D

3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.

InterPro

IPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]

PANTHER

PTHR11986. PTHR11986. 1 hit.

Pfam

PF00202. Aminotran_3. 1 hit.
[Graphical view]

SUPFAM

SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.

TIGRFAMs

TIGR00700. GABAtrnsam. 1 hit.

PROSITE

PS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

B1MIQ9_MYCA9

Accession

Primary (citable) accession number: B1MIQ9

Entry history

Integrated into UniProtKB/TrEMBL:	April 29, 2008
Last sequence update:	April 29, 2008
Last modified:	May 1, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)