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B1MIQ9

- B1MIQ9_MYCA9

UniProt

B1MIQ9 - B1MIQ9_MYCA9

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Protein
Submitted name:

4-aminobutyrate aminotransferase (GabT)

Gene
MAB_4207
Organism
Mycobacterium abscessus (strain ATCC 19977 / DSM 44196)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. 4-aminobutyrate transaminase activity Source: InterPro
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. gamma-aminobutyric acid metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseImported, Transferase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciMABS36809-WGS:GSQO-4226-MONOMER.
MABS561007:GJTG-4226-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
4-aminobutyrate aminotransferase (GabT)Imported
Gene namesi
Ordered Locus Names:MAB_4207Imported
OrganismiMycobacterium abscessus (strain ATCC 19977 / DSM 44196)
Taxonomic identifieri561007 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium abscessus
ProteomesiUP000007137: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi561007.MAB_4207.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4FFCX-ray1.80A/B/C/D1-449[»]
ProteinModelPortaliB1MIQ9.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0160.
HOGENOMiHOG000020206.
KOiK07250.
OMAiRMPMAYP.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00700. GABAtrnsam. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1MIQ9-1 [UniParc]FASTAAdd to Basket

« Hide

MTDITYRLAQ KRTIVTPLPG PRSGALAERR RAAVSAGVGS TAPVYAVDAD    50
GGVIVDADGN SFIDLGAGIA VTTVGASHPA VAAAIADQAT HFTHTCFMVT 100
PYEGYVQVAE LLNALTPGDH DKRTALFNSG AEAVENAIKV ARLATGRPAV 150
VAFDNAYHGR TNLTMALTAK SMPYKSQFGP FAPEVYRMPA SYPLRDEPGL 200
TGEEAARRAI SRIETQIGAQ SLAAIIIEPI QGEGGFIVPA PGFLATLTAW 250
ASENGVVFIA DEVQTGFART GAWFASEHEG IVPDIVTMAK GIAGGMPLSA 300
VTGRAELMDA VYAGGLGGTY GGNPVTCAAA VAALGVMREL DLPARARAIE 350
ASVTSRLSAL AEEVDIIGEV RGRGAMLAIE IVKPGTLEPD AALTKSIAAE 400
ALSQGVLILT CGTFGNVIRL LPPLVIGDDL LDEGITALSD IIRAKASHQ 449
Length:449
Mass (Da):46,413
Last modified:April 29, 2008 - v1
Checksum:i83EC8057A80BF883
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU458896 Genomic DNA. Translation: CAM64280.1.
RefSeqiYP_001704934.1. NC_010397.1.

Genome annotation databases

EnsemblBacteriaiCAM64280; CAM64280; MAB_4207.
GeneIDi5966669.
KEGGimab:MAB_4207.
PATRICi17980240. VBIMycAbs55940_4285.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU458896 Genomic DNA. Translation: CAM64280.1 .
RefSeqi YP_001704934.1. NC_010397.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4FFC X-ray 1.80 A/B/C/D 1-449 [» ]
ProteinModelPortali B1MIQ9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 561007.MAB_4207.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAM64280 ; CAM64280 ; MAB_4207 .
GeneIDi 5966669.
KEGGi mab:MAB_4207.
PATRICi 17980240. VBIMycAbs55940_4285.

Phylogenomic databases

eggNOGi COG0160.
HOGENOMi HOG000020206.
KOi K07250.
OMAi RMPMAYP.

Enzyme and pathway databases

BioCyci MABS36809-WGS:GSQO-4226-MONOMER.
MABS561007:GJTG-4226-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProi IPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view ]
PANTHERi PTHR11986. PTHR11986. 1 hit.
Pfami PF00202. Aminotran_3. 1 hit.
[Graphical view ]
PIRSFi PIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMi SSF53383. SSF53383. 1 hit.
TIGRFAMsi TIGR00700. GABAtrnsam. 1 hit.
PROSITEi PS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Acquisition of foreign virulence genes by the cystic fibrosis pathogen Mycobacterium abscessus."
    Genoscope
    Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L., Gaillard J.L.
    Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 19977 / DSM 44196.
  2. "Crystal structure of a 4-aminobutyrate aminotransferase (GabT) from Mycobacterium abscessus."
    Seattle Structural Genomics Center for Infectious Disease (SSGCID)
    Edwards T.E., Fox III D., Abendroth J.
    Submitted (MAY-2012) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS).

Entry informationi

Entry nameiB1MIQ9_MYCA9
AccessioniPrimary (citable) accession number: B1MIQ9
Entry historyi
Integrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: July 9, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome

External Data

Dasty 3

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