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B1MIQ9

- B1MIQ9_MYCA9

UniProt

B1MIQ9 - B1MIQ9_MYCA9

Protein
Submitted name:

4-aminobutyrate aminotransferase (GabT)

Gene

MAB_4207

Organism
Mycobacterium abscessus (strain ATCC 19977 / DSM 44196)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 41 (01 Oct 2014)
      Sequence version 1 (29 Apr 2008)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. 4-aminobutyrate transaminase activity Source: InterPro
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. gamma-aminobutyric acid metabolic process Source: InterPro

    Keywords - Molecular functioni

    AminotransferaseImported, Transferase

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Enzyme and pathway databases

    BioCyciMABS36809-WGS:GSQO-4226-MONOMER.
    MABS561007:GJTG-4226-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    4-aminobutyrate aminotransferase (GabT)Imported
    Gene namesi
    Ordered Locus Names:MAB_4207Imported
    OrganismiMycobacterium abscessus (strain ATCC 19977 / DSM 44196)Imported
    Taxonomic identifieri561007 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium abscessus
    ProteomesiUP000007137: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi561007.MAB_4207.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4FFCX-ray1.80A/B/C/D1-449[»]
    ProteinModelPortaliB1MIQ9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0160.
    HOGENOMiHOG000020206.
    KOiK07250.
    OMAiRMPMAYP.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProiIPR004632. 4NH2But_aminotransferase_bac.
    IPR005814. Aminotrans_3.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    [Graphical view]
    PANTHERiPTHR11986. PTHR11986. 1 hit.
    PfamiPF00202. Aminotran_3. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
    SUPFAMiSSF53383. SSF53383. 1 hit.
    TIGRFAMsiTIGR00700. GABAtrnsam. 1 hit.
    PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B1MIQ9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTDITYRLAQ KRTIVTPLPG PRSGALAERR RAAVSAGVGS TAPVYAVDAD    50
    GGVIVDADGN SFIDLGAGIA VTTVGASHPA VAAAIADQAT HFTHTCFMVT 100
    PYEGYVQVAE LLNALTPGDH DKRTALFNSG AEAVENAIKV ARLATGRPAV 150
    VAFDNAYHGR TNLTMALTAK SMPYKSQFGP FAPEVYRMPA SYPLRDEPGL 200
    TGEEAARRAI SRIETQIGAQ SLAAIIIEPI QGEGGFIVPA PGFLATLTAW 250
    ASENGVVFIA DEVQTGFART GAWFASEHEG IVPDIVTMAK GIAGGMPLSA 300
    VTGRAELMDA VYAGGLGGTY GGNPVTCAAA VAALGVMREL DLPARARAIE 350
    ASVTSRLSAL AEEVDIIGEV RGRGAMLAIE IVKPGTLEPD AALTKSIAAE 400
    ALSQGVLILT CGTFGNVIRL LPPLVIGDDL LDEGITALSD IIRAKASHQ 449
    Length:449
    Mass (Da):46,413
    Last modified:April 29, 2008 - v1
    Checksum:i83EC8057A80BF883
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU458896 Genomic DNA. Translation: CAM64280.1.
    RefSeqiYP_001704934.1. NC_010397.1.

    Genome annotation databases

    EnsemblBacteriaiCAM64280; CAM64280; MAB_4207.
    GeneIDi5966669.
    KEGGimab:MAB_4207.
    PATRICi17980240. VBIMycAbs55940_4285.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU458896 Genomic DNA. Translation: CAM64280.1 .
    RefSeqi YP_001704934.1. NC_010397.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4FFC X-ray 1.80 A/B/C/D 1-449 [» ]
    ProteinModelPortali B1MIQ9.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 561007.MAB_4207.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAM64280 ; CAM64280 ; MAB_4207 .
    GeneIDi 5966669.
    KEGGi mab:MAB_4207.
    PATRICi 17980240. VBIMycAbs55940_4285.

    Phylogenomic databases

    eggNOGi COG0160.
    HOGENOMi HOG000020206.
    KOi K07250.
    OMAi RMPMAYP.

    Enzyme and pathway databases

    BioCyci MABS36809-WGS:GSQO-4226-MONOMER.
    MABS561007:GJTG-4226-MONOMER.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProi IPR004632. 4NH2But_aminotransferase_bac.
    IPR005814. Aminotrans_3.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    [Graphical view ]
    PANTHERi PTHR11986. PTHR11986. 1 hit.
    Pfami PF00202. Aminotran_3. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
    SUPFAMi SSF53383. SSF53383. 1 hit.
    TIGRFAMsi TIGR00700. GABAtrnsam. 1 hit.
    PROSITEi PS00600. AA_TRANSFER_CLASS_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Acquisition of foreign virulence genes by the cystic fibrosis pathogen Mycobacterium abscessus."
      Genoscope
      Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L., Gaillard J.L.
      Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 19977 / DSM 44196Imported.
    2. "Crystal structure of a 4-aminobutyrate aminotransferase (GabT) from Mycobacterium abscessus."
      Seattle Structural Genomics Center for Infectious Disease (SSGCID)
      Edwards T.E., Fox III D., Abendroth J.
      Submitted (MAY-2012) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS).

    Entry informationi

    Entry nameiB1MIQ9_MYCA9
    AccessioniPrimary (citable) accession number: B1MIQ9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 29, 2008
    Last sequence update: April 29, 2008
    Last modified: October 1, 2014
    This is version 41 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3