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B1MHS6 (B1MHS6_MYCA9) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
60 kDa chaperonin HAMAP-Rule MF_00600
Alternative name(s):
GroEL protein HAMAP-Rule MF_00600
Protein Cpn60 HAMAP-Rule MF_00600
Gene names
Name:groL HAMAP-Rule MF_00600
Synonyms:groEL HAMAP-Rule MF_00600
Ordered Locus Names:MAB_0650 EMBL CAM60748.1
OrganismMycobacterium abscessus (strain ATCC 19977 / DSM 44196) [Complete proteome] [HAMAP]
Taxonomic identifier561007 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium abscessus

Protein attributes

Sequence length541 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions By similarity. HAMAP-Rule MF_00600 RuleBase RU000419

Subunit structure

Oligomer of 14 subunits composed of two stacked rings of 7 subunits By similarity. HAMAP-Rule MF_00600 RuleBase RU000419

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00600.

Sequence similarities

Belongs to the chaperonin (HSP60) family. HAMAP-Rule MF_00600 RuleBase RU000418

Ontologies

Keywords
   Cellular componentCytoplasm HAMAP-Rule MF_00600
   LigandATP-binding HAMAP-Rule MF_00600 RuleBase RU003319
Nucleotide-binding
   Molecular functionChaperone HAMAP-Rule MF_00600 RuleBase RU003319
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processprotein refolding

Inferred from electronic annotation. Source: HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
B1MHS6 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: 13ED4CC1153F4FCB

FASTA54156,389
        10         20         30         40         50         60 
MAKTIAYDEE ARRGLERGLN ALADAVKVTL GPKGRNVVLE KKWGAPTITN DGVSIAKEIE 

        70         80         90        100        110        120 
LEDPYEKIGA ELVKEVAKKT DDVAGDGTTT ATVLAQALVK EGLRNVAAGA NPLGLKRGIE 

       130        140        150        160        170        180 
KAVEKVTETL LKSAKEVETK EQIAATAGIS AGDQSIGDLI AEAMDKVGNE GVITVEESNT 

       190        200        210        220        230        240 
FGLQLELTEG MRFDKGYISG YFVTDAERQE AVLEDPYILL VSSKVSTVKD LLPLLEKVIQ 

       250        260        270        280        290        300 
AGKPLLIIAE DVEGEALSTL VVNKIRGTFK SVAVKAPGFG DRRKAMLQDM AILTGGQVVS 

       310        320        330        340        350        360 
EEVGLSLETA DITLLGTARK VVVTKDETTI VEGAGDSDAI AGRVAQIRSE IENSDSDYDR 

       370        380        390        400        410        420 
EKLQERLAKL AGGVAVIKAG AATEVELKER KHRIEDAVRN AKAAVEEGIV AGGGVALLQA 

       430        440        450        460        470        480 
APSLDELSLT GDEATGAAIV KVAVEAPLKQ IAFNSGLEPG VVAEKVRNSP SGTGLNAATG 

       490        500        510        520        530        540 
EYEDLLAAGV ADPVKVTRSA LQNAASIAAL FLTTEAVVAD KPEKAAAPAG DPTGGMGGMD 


F

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References

[1]"Acquisition of foreign virulence genes by the cystic fibrosis pathogen Mycobacterium abscessus."
Genoscope
Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L., Gaillard J.L.
Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 19977 / DSM 44196.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CU458896 Genomic DNA. Translation: CAM60748.1.
RefSeqYP_001701402.1. NC_010397.1.

3D structure databases

ProteinModelPortalB1MHS6.
SMRB1MHS6. Positions 2-524.
ModBaseSearch...

Protein-protein interaction databases

STRING561007.MAB_0650.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAM60748; CAM60748; MAB_0650.
GeneID5963186.
KEGGmab:MAB_0650.
PATRIC17972971. VBIMycAbs55940_0689.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0459.
HOGENOMHOG000076290.
KOK04077.
OMATAIKDII.
ProtClustDBPRK00013.

Enzyme and pathway databases

BioCycMABS561007:GJTG-655-MONOMER.

Family and domain databases

HAMAPMF_00600. CH60.
InterProIPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
[Graphical view]
PANTHERPTHR11353. PTHR11353. 1 hit.
PfamPF00118. Cpn60_TCP1. 1 hit.
[Graphical view]
PRINTSPR00298. CHAPERONIN60.
SUPFAMSSF48592. GroEL-ATPase. 1 hit.
TIGRFAMsTIGR02348. GroEL. 1 hit.
PROSITEPS00296. CHAPERONINS_CPN60. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB1MHS6_MYCA9
AccessionPrimary (citable) accession number: B1MHS6
Entry history
Integrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: May 1, 2013
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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