B1MHP2 (B1MHP2_MYCA9) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase HAMAP MF_01039
Short name=BPG-dependent PGAM HAMAP MF_01039
Short name=PGAM HAMAP MF_01039
Short name=Phosphoglyceromutase HAMAP MF_01039
Short name=dPGM HAMAP MF_01039
EC=5.4.2.1 HAMAP MF_01039

Gene names

Name:	gpmA HAMAP MF_01039
Ordered Locus Names:	MAB_4049c

Organism

Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) [Complete proteome] [HAMAP]

Taxonomic identifier

561007 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium abscessus

Protein attributes

Sequence length	256 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP MF_01039 RuleBase RU004512
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01039 RuleBase RU004512 SAAS SAAS005952
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01039 RuleBase RU004512
Sequence similarities	Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily. HAMAP MF_01039

Ontologies

Keywords
Biological process	Glycolysis HAMAP MF_01039 SAAS SAAS005952
Molecular function	Isomerase HAMAP MF_01039 SAAS SAAS005952
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: HAMAP
Molecular function	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	19	1	Tele-phosphohistidine intermediate By similarity HAMAP MF_01039
	Active site	190	1	By similarity HAMAP MF_01039
	Site	70	1	Interaction with carboxyl group of phosphoglycerates By similarity HAMAP MF_01039

Sequences

	Sequence		Length	Mass (Da)
	B1MHP2 [UniParc]. Last modified April 29, 2008. Version 1. Checksum: 4680D46352A484F5	FASTA	256	28,064
	10 20 30 40 50 60 MSGETSSKTN GATLILLRHG ESQWNAKNLF TGWVDVDLTE KGRSEAQRGG ELLAQQGLLP 70 80 90 100 110 120 DILFTSLLRR AINTAHLALD TADRLWIPVV RDWRLNERHY GALQGLDKAE TKAKYGEEQF 130 140 150 160 170 180 MAWRRSYDTP PPPIERGSHY SQDQDPRYAD IDGGPLTECL ADVVARFVPY YEEAIVPELR 190 200 210 220 230 240 AGKTVLVAAH GNSLRALVKY LDGISDEEIV GLNIPTGIPL RYDLDENLKP VTPGGVYLDP 250 EAAAAGAAAV ANQGAK

References

[1]

"Acquisition of foreign virulence genes by the cystic fibrosis pathogen Mycobacterium abscessus." Genoscope Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L., Gaillard J.L. Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU458896 Genomic DNA. Translation: CAM64123.1.
RefSeq	YP_001704777.1. NC_010397.1.
3D structure databases
ProteinModelPortal	B1MHP2.
SMR	B1MHP2. Positions 10-246.
ModBase	Search...
Protein-protein interaction databases
STRING	B1MHP2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000008443; EBMYCP00000008382; EBMYCG00000008441.
GeneID	5966512.
GenomeReviews	Gene locus MAB_4049c in contig CU458896_GR.
KEGG	mab:MAB_4049c.
PATRIC	17979920. VBIMycAbs55940_4125.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000015087.
HOGENOM	HBG658938.
OMA	EWNALNL.
ProtClustDB	CLSK2319866.
Family and domain databases
HAMAP	MF_01039. PGAM_GpmA. [Tree]
InterPro	IPR013078. His_Pase_superF_clade-1. IPR001345. PG/BPGM_mutase_AS. IPR005952. Phosphogly_mut1. [Graphical view]
KO	K01834.
PANTHER	PTHR11931. Phosphogly_mut1. 1 hit.
Pfam	PF00300. His_Phos_1. 1 hit. [Graphical view]
SMART	SM00855. PGAM. 1 hit. [Graphical view]
TIGRFAMs	TIGR01258. Pgm_1. 1 hit.
PROSITE	PS00175. PG_MUTASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B1MHP2_MYCA9

Accession

Primary (citable) accession number: B1MHP2

Entry history

Integrated into UniProtKB/TrEMBL:	April 29, 2008
Last sequence update:	April 29, 2008
Last modified:	December 14, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)