B1MGA0 (RS4_MYCA9) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
30S ribosomal protein S4

Gene names

Name:	rpsD
Ordered Locus Names:	MAB_3771c

Organism

Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) [Complete proteome] [HAMAP]

Taxonomic identifier

561007 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium abscessus

Protein attributes

Sequence length	201 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit By similarity. HAMAP MF_01306_B With S5 and S12 plays an important role in translational accuracy By similarity. HAMAP MF_01306_B
Subunit structure	Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity By similarity.
Sequence similarities	Belongs to the ribosomal protein S4P family. Contains 1 S4 RNA-binding domain.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	small ribosomal subunit Inferred from electronic annotation. Source: InterPro
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 201	201	30S ribosomal protein S4 HAMAP MF_01306_B		PRO_1000140762
Regions
	Domain	91 – 157	67	S4 RNA-binding

Sequences

	Sequence		Length	Mass (Da)
	B1MGA0 [UniParc]. Last modified April 29, 2008. Version 1. Checksum: 635DC24575826D00	FASTA	201	23,199
	10 20 30 40 50 60 MARYTGPVTR KSRRLGVDLV GGSSAYEKRP YPPGQHGRAR IKESEYRQQL QEKQKARFTY 70 80 90 100 110 120 GVMEKQFRRY YAEAVRSSGK TGEQLLQILE SRLDNVVYRA GLARTRRMAR QLVSHGHFTV 130 140 150 160 170 180 NNVKVDVPSY RVSQYDIIDI KPKSLNTLPF EVARETAGER PIPGWLQVVG ERQRILVHQL 190 200 PERAQIDVPL AEQLIVEFYS K

References

[1]

"Acquisition of foreign virulence genes by the cystic fibrosis pathogen Mycobacterium abscessus." Genoscope Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L., Gaillard J.L. Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 19977 / DSM 44196.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU458896 Genomic DNA. Translation: CAM63845.1.
RefSeq	YP_001704499.1. NC_010397.1.
3D structure databases
ProteinModelPortal	B1MGA0.
ModBase	Search...
Protein-protein interaction databases
STRING	B1MGA0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000004394; EBMYCP00000004333; EBMYCG00000004392.
GeneID	5966266.
GenomeReviews	Gene locus MAB_3771c in contig CU458896_GR.
KEGG	mab:MAB_3771c.
PATRIC	17979344. VBIMycAbs55940_3841.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000017415.
HOGENOM	HBG285740.
OMA	QLVVELY.
ProtClustDB	PRK05327.
Enzyme and pathway databases
BioCyc	MABS561007:MAB_3771C-MONOMER.
Family and domain databases
HAMAP	MF_01306_B. Ribosomal_S4_B. [Tree]
InterPro	IPR022801. Ribosomal_S4/S9. IPR001912. Ribosomal_S4/S9_N. IPR005709. Ribosomal_S4_bac-type. IPR018079. Ribosomal_S4_CS. IPR002942. S4_RNA-bd. [Graphical view]
Gene3D	G3DSA:1.10.1050.10. G3DSA:1.10.1050.10. 1 hit. G3DSA:3.10.290.10. G3DSA:3.10.290.10. 1 hit.
KO	K02986.
PANTHER	PTHR11831. Ribosomal_S4. 1 hit.
Pfam	PF00163. Ribosomal_S4. 1 hit. PF01479. S4. 1 hit. [Graphical view]
SMART	SM00363. S4. 1 hit. [Graphical view]
TIGRFAMs	TIGR01017. RpsD_bact. 1 hit.
PROSITE	PS00632. RIBOSOMAL_S4. 1 hit. PS50889. S4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RS4_MYCA9

Accession

Primary (citable) accession number: B1MGA0

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	April 29, 2008
Last modified:	January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program