B1MG63 (GCP_MYCA9) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	MAB_3734c

Organism

Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) [Complete proteome] [HAMAP]

Taxonomic identifier

561007 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium abscessus

Protein attributes

Sequence length	344 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 344	344	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_1000145998

Sequences

	Sequence		Length	Mass (Da)
	B1MG63 [UniParc]. Last modified April 29, 2008. Version 1. Checksum: 2789CB817A1897FC	FASTA	344	34,947
	10 20 30 40 50 60 MTVILAIESS CDETGVGIAE LTPDGSVVLL ADEVASSVEE HARFGGVVPE IASRAHLEAL 70 80 90 100 110 120 GVTARRALDL AGVQRPDVVA ATIGPGLAGA LLVGVSAAKG LALAWGVPFY GVNHLGGHIA 130 140 150 160 170 180 ADVYENGPLP ECVALLVSGG HTSLLHVRSL AEPIEELGAT VDDAAGEAYD KVARLLGLGY 190 200 210 220 230 240 PGGKVLDELA QQGDSSAVPF PRGMTGPRDA RHSFSFSGLK TAVARYLEKH GVEADFSPAD 250 260 270 280 290 300 VAAGFQEAVA DVLTMKAVRA ATDLGVSTLL IAGGVAANSR VRALAEQRCA ETGLTLRVPP 310 320 330 340 LRLCTDNGAM IASFAAHLVA AGAQPSSLQA AADPGLPVVK GQVH

References

[1]

"Acquisition of foreign virulence genes by the cystic fibrosis pathogen Mycobacterium abscessus." Genoscope Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L., Gaillard J.L. Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 19977 / DSM 44196.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU458896 Genomic DNA. Translation: CAM63808.1.
RefSeq	YP_001704462.1. NC_010397.1.
3D structure databases
ProteinModelPortal	B1MG63.
ModBase	Search...
Protein-protein interaction databases
STRING	B1MG63.
Protein family/group databases
MEROPS	M22.A01.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000007110; EBMYCP00000007049; EBMYCG00000007108.
GeneID	5966232.
GenomeReviews	Gene locus MAB_3734c in contig CU458896_GR.
KEGG	mab:MAB_3734c.
PATRIC	17979268. VBIMycAbs55940_3803.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000017447.
HOGENOM	HBG304663.
OMA	PLYGVNH.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	MABS561007:MAB_3734C-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_MYCA9

Accession

Primary (citable) accession number: B1MG63

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	April 29, 2008
Last modified:	January 25, 2012
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program