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Reviewed, UniProtKB/Swiss-Prot B1MFZ9 (ADD_MYCA9)

Last modified February 9, 2010. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Adenosine deaminase
    EC=3.5.4.4
Alternative name(s):
    Adenosine aminohydrolase
Gene names
Name: add
Ordered Locus Names: MAB_3670c
OrganismMycobacterium abscessus (strain ATCC 19977 / DSM 44196) [Complete proteome] [HAMAP]
Taxonomic identifier561007 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium abscessus

Protein attributes

Sequence length362 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

Adenosine + H2O = inosine + NH3. HAMAP MF_00540

Sequence similarities

Belongs to the adenosine and AMP deaminases family.

Ontologies

Keywords
   Biological processNucleotide metabolism
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processpurine ribonucleoside monophosphate biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Molecular functionadenosine deaminase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 362362Adenosine deaminase HAMAP MF_00540
PRO_1000128851

Sites

Active site2081 Potential
Active site2671 Potential
Active site3001 Potential
Active site3011 Potential

Sequences

Sequence LengthMass (Da)Tools
B1MFZ9-1 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: 03473A10F7CC0BF6

FASTA36239,375
        10         20         30         40         50         60 
MTAELDLVSI TQAPKALLHD HLDGGLRPGT VLDLARETGY ENLPAQDETA LASWFRTAAD 

        70         80         90        100        110        120 
SGSLEQYLET FAHTVGVMQT ASALHRVAAE CVEDLAADGV VYAEVRFAPE LHIDAGLTLD 

       130        140        150        160        170        180 
DVMDAVLAGF ADGERQASAA GKRIKVRTLV TAMRHAARSR EIAELAVKFR DRGAVGFDIA 

       190        200        210        220        230        240 
GAEAGYPPTR HLDAFEYMRN ANSRFTIHAG EGFGLPSIHE AIAFCGADRL GHGVRIVDDI 

       250        260        270        280        290        300 
DIGPDGTAHL GRLSSLLRDK RVPLELCPSS NVQTGAVESL ADHPFDLLAR LRFRVTVNTD 

       310        320        330        340        350        360 
NRLMSDTTMS REMLRLVETF GYGWSDLQRF TINAMKSAFI PFDERLAIID DVIKPGYAVL 


IG 

« Hide

References

[1]"Acquisition of foreign virulence genes by the cystic fibrosis pathogen Mycobacterium abscessus."
Genoscope
Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L., Gaillard J.L.
Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU458896 Genomic DNA. Translation: CAM63744.1.
RefSeqYP_001704398.1.

3D structure databases

SMRB1MFZ9. Positions 12-354.
ModBaseSearch...

Genome annotation databases

GeneID5966168.
GenomeReviewsGene locus MAB_3670c in contig CU458896_GR.
KEGGmab:MAB_3670c.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG630382.
OMAFLKKLDW.

Family and domain databases

HAMAPMF_00540. A_deaminase.
[Tree]
InterProIPR001365. A/AMP_deaminase.
IPR006330. A_deaminase.
[Graphical view]
PANTHERPTHR11409. A/AMP_deaminase. 1 hit.
PfamPF00962. A_deaminase. 1 hit.
[Graphical view]
TIGRFAMsTIGR01430. aden_deam. 1 hit.
PROSITEPS00485. A_DEAMINASE. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameADD_MYCA9
AccessionPrimary (citable) accession number: B1MFZ9
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 29, 2008
Last modified: February 9, 2010
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents