B1MFC0 (PATR_MYCA9) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative phenylalanine aminotransferase
EC=2.6.1.-

Gene names

Name:	pat
Ordered Locus Names:	MAB_0220c

Organism

Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) [Complete proteome] [HAMAP]

Taxonomic identifier

561007 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium abscessus

Protein attributes

Sequence length	347 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May catalyze the transamination reaction in phenylalanine biosynthesis By similarity. HAMAP MF_01513
Cofactor	Pyridoxal phosphate By similarity. HAMAP MF_01513
Sequence similarities	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

Ontologies

Keywords
Ligand	Pyridoxal phosphate
Molecular function	Aminotransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	histidine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	histidinol-phosphate transaminase activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 347	347	Putative phenylalanine aminotransferase HAMAP MF_01513		PRO_1000146150
Amino acid modifications
	Modified residue	214	1	N6-(pyridoxal phosphate)lysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	B1MFC0 [UniParc]. Last modified April 29, 2008. Version 1. Checksum: 7D3A0788BCE5C61B	FASTA	347	37,500
	10 20 30 40 50 60 MPARLRPELT ELPAYTPGRN VPGAIKLASN ETVQEPLPSV RAALAEAGSL INRYPDNGYA 70 80 90 100 110 120 ELRSHLAKHV DMPPEHIAVG CGSVSLCQQL VQITATVGDE VLFGWRSFET YPLVVRVAGA 130 140 150 160 170 180 TPVQVPLVDH TYDLAAMAAA VTDVTRLIFV CNPNNPTGTV VRPAELRRFV ESVPPHILIA 190 200 210 220 230 240 IDEAYVEYVR EDFTDSLALV REHPNVVVLR TFSKAYGLAG LRVGYAVGDP DVITTLGKVY 250 260 270 280 290 300 VPFSASSLAQ AAAVASLGAA EELLARTNDV VTERARVTSA LREAGYQVPP SQANFVWLPL 310 320 330 340 GERSTEFAQA SAEARIIVRP FGTDGVRVTI GAPMENDAFL KFSRAWR

References

[1]

"Acquisition of foreign virulence genes by the cystic fibrosis pathogen Mycobacterium abscessus." Genoscope Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L., Gaillard J.L. Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 19977 / DSM 44196.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU458896 Genomic DNA. Translation: CAM60320.1.
RefSeq	YP_001700974.1. NC_010397.1.
3D structure databases
ProteinModelPortal	B1MFC0.
ModBase	Search...
Protein-protein interaction databases
STRING	B1MFC0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000007152; EBMYCP00000007091; EBMYCG00000007150.
GeneID	5962763.
GenomeReviews	Gene locus MAB_0220c in contig CU458896_GR.
KEGG	mab:MAB_0220c.
PATRIC	17972089. VBIMycAbs55940_0254.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00070000031717.
HOGENOM	HBG646350.
OMA	YEYAEAE.
ProtClustDB	PRK03321.
Enzyme and pathway databases
BioCyc	MABS561007:MAB_0220C-MONOMER.
Family and domain databases
HAMAP	MF_01513. Phe_aminotrans_2. [Tree]
InterPro	IPR001917. Aminotrans_II_pyridoxalP_BS. IPR004839. Aminotransferase_I/II. IPR024892. AroT. IPR005861. HisP_aminotrans. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00817.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01141. HisC. 1 hit.
PROSITE	PS00599. AA_TRANSFER_CLASS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PATR_MYCA9

Accession

Primary (citable) accession number: B1MFC0

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	April 29, 2008
Last modified:	January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program