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B1MF16 (B1MF16_MYCA9) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210 RuleBase RU000531

EC=2.5.1.19 HAMAP MF_00210 RuleBase RU000531
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase HAMAP MF_00210
Gene names
Name:aroA HAMAP MF_00210
Ordered Locus Names:MAB_3546
OrganismMycobacterium abscessus (strain ATCC 19977 / DSM 44196) [Complete proteome] [HAMAP]
Taxonomic identifier561007 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium abscessus

Protein attributes

Sequence length431 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210 RuleBase RU000531

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family. HAMAP MF_00210 RuleBase RU004164

Sequences

Sequence LengthMass (Da)Tools
B1MF16 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: 8220ECFBE3FEFCA7

FASTA43144,520
        10         20         30         40         50         60 
MTSGLWQAPT IDGSICATIT MPGSKSQTNR ALVLAALAAR EGGTSTVSGA LRSRDTDLMI 

        70         80         90        100        110        120 
RALRSLGFDI IGDGTDLTVS PGAGDDDAST VDCGLAGTVL RFLPPVAALR HAPTVFDGDE 

       130        140        150        160        170        180 
QARARPIAPL LDALRSTGVG IDGQHLPFTV TGTGQVQGGE VGVDASGSSQ FVSGLLLSGA 

       190        200        210        220        230        240 
AFSAGLTAMN TADVLPSGPH VVMTVTMLRE AGIAVDDSVP GRWRIDPQPI PAHQWVIEPD 

       250        260        270        280        290        300 
LSNALAFIAP ALATGGTVRI TGWPRQSTQP ARQIEDVVRQ FAQTVSLTDT HLEVTGQSGY 

       310        320        330        340        350        360 
GGVDLDLSEV GELTPTVAAL SALAESGAVS TLRGIAHLRG HETDRLKALA HEINALGGRC 

       370        380        390        400        410        420 
EETQDGLRIV ATDLRGGVWG SYADHRMATA GALVGLKVPG VSVDDIATTS KTLPDFPGMW 

       430 
ADMIAQSERA S 

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References

[1]"Acquisition of foreign virulence genes by the cystic fibrosis pathogen Mycobacterium abscessus."
Genoscope
Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L., Gaillard J.L.
Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU458896 Genomic DNA. Translation: CAM63622.1.
RefSeqYP_001704276.1. NC_010397.1.

3D structure databases

ProteinModelPortalB1MF16.
SMRB1MF16. Positions 6-425.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1MF16.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000004977; EBMYCP00000004916; EBMYCG00000004975.
GeneID5966046.
GenomeReviewsGene locus MAB_3546 in contig CU458896_GR.
KEGGmab:MAB_3546.
PATRIC17978894. VBIMycAbs55940_3616.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000016231.
HOGENOMHBG646626.
OMAHRMATAG.
ProtClustDBPRK02427.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB1MF16_MYCA9
AccessionPrimary (citable) accession number: B1MF16
Entry history
Integrated into UniProtKB/TrEMBL: April 29, 2008
Last sequence update: April 29, 2008
Last modified: December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)