B1MEU3 (SSRP_MYCA9) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
SsrA-binding protein

Gene names

Name:	smpB
Ordered Locus Names:	MAB_3473c

Organism

Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) [Complete proteome] [HAMAP]

Taxonomic identifier

561007 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium abscessus

Protein attributes

Sequence length	159 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes By similarity. HAMAP MF_00023
Subcellular location	Cytoplasm Potential HAMAP MF_00023.
Sequence similarities	Belongs to the SmpB family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	RNA-binding
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	RNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 159	159	SsrA-binding protein HAMAP MF_00023		PRO_1000090166

Sequences

	Sequence		Length	Mass (Da)
	B1MEU3 [UniParc]. Last modified April 29, 2008. Version 1. Checksum: 72D5EEE064CA0E2F	FASTA	159	17,890
	10 20 30 40 50 60 MSKKPADGRK VIATNRKARH NYSIIDVYEA GVQLVGTEVK TLREGKASLV DAFATVDDGE 70 80 90 100 110 120 VWLRGVHIPQ YDHGTWTNHA PLRNRKLLLH RAQIDMLVGK TRDGNLTLVP LSLYFLDGKV 130 140 150 KVELALARGK QAHDKRQDIA KRDASREITR ELGRRAKGM

References

[1]

"Acquisition of foreign virulence genes by the cystic fibrosis pathogen Mycobacterium abscessus." Genoscope Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L., Gaillard J.L. Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 19977 / DSM 44196.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU458896 Genomic DNA. Translation: CAM63549.1.
RefSeq	YP_001704203.1. NC_010397.1.
3D structure databases
ProteinModelPortal	B1MEU3.
ModBase	Search...
Protein-protein interaction databases
STRING	B1MEU3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000007036; EBMYCP00000006975; EBMYCG00000007034.
GeneID	5965973.
GenomeReviews	Gene locus MAB_3473c in contig CU458896_GR.
KEGG	mab:MAB_3473c.
PATRIC	17978742. VBIMycAbs55940_3541.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000017126.
HOGENOM	HBG293422.
OMA	EKYEAGI.
Enzyme and pathway databases
BioCyc	MABS561007:MAB_3473C-MONOMER.
Family and domain databases
HAMAP	MF_00023. SmpB. [Tree]
InterPro	IPR023620. SmpB. IPR000037. SsrA-bd_prot. [Graphical view]
Gene3D	G3DSA:2.40.280.10. SmpB. 1 hit.
KO	K03664.
Pfam	PF01668. SmpB. 1 hit. [Graphical view]
ProDom	PD004488. SmpB. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF74982. SmpB. 1 hit.
TIGRFAMs	TIGR00086. SmpB. 1 hit.
PROSITE	PS01317. SSRP. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SSRP_MYCA9

Accession

Primary (citable) accession number: B1MEU3

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	April 29, 2008
Last modified:	January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program