B1MDL3 (B1MDL3_MYCA9) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Ribonuclease III Rnc EMBL CAM63332.1

Gene names

Ordered Locus Names:

MAB_3256c

Organism

Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) [Complete proteome] [HAMAP]

Taxonomic identifier

561007 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium abscessus

Protein attributes

Sequence length	258 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs By similarity. SAAS SAAS011907
Catalytic activity	Endonucleolytic cleavage to 5'-phosphomonoester. SAAS SAAS011907
Subcellular location	Cytoplasm By similarity SAAS SAAS011907.
Sequence similarities	Contains 1 DRBM (double-stranded RNA-binding) domain. SAAS SAAS011907 Contains 1 RNase III domain. SAAS SAAS011907

Ontologies

Keywords
Cellular component	Cytoplasm SAAS SAAS011907
Ligand	RNA-binding SAAS SAAS011907
Molecular function	Endonuclease SAAS SAAS011907 Hydrolase Nuclease
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	RNA processing Inferred from electronic annotation. Source: InterPro rRNA catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	double-stranded RNA binding Inferred from electronic annotation. Source: InterPro ribonuclease III activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1MDL3 [UniParc]. Last modified April 29, 2008. Version 1. Checksum: 241BCAB2A7F06E31	FASTA	258	27,076
	10 20 30 40 50 60 MSRTPEHRHD DLRAAIGVQL GDELLTLALT HRSYAYENGG LPTNERLEFL GDAVLGLTIT 70 80 90 100 110 120 ETLYHSHPDR SEGDLAKLRA SIVNTQALAG VARGLTGDGL GAHLLLGKGE ENTGGRDKSS 130 140 150 160 170 180 ILADGMESIL GAVYLEHGLE TARAVVLTLF GELLETAPKL GAGLDWKTSL QELTAEKGWG 190 200 210 220 230 240 APSYAVTSTG PDHDKEFTAT VMVNDTAHGV GVGRSKKEAE QKAAAEAWNS ISGDEPLGGR 250 AEGGDEPLEG RAEGTVSA

References

[1]

"Acquisition of foreign virulence genes by the cystic fibrosis pathogen Mycobacterium abscessus." Genoscope Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L., Gaillard J.L. Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU458896 Genomic DNA. Translation: CAM63332.1.
RefSeq	YP_001703986.1. NC_010397.1.
3D structure databases
ProteinModelPortal	B1MDL3.
SMR	B1MDL3. Positions 15-158.
ModBase	Search...
Protein-protein interaction databases
STRING	B1MDL3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000005543; EBMYCP00000005482; EBMYCG00000005541.
GeneID	5965757.
GenomeReviews	Gene locus MAB_3256c in contig CU458896_GR.
KEGG	mab:MAB_3256c.
PATRIC	17978284. VBIMycAbs55940_3315.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000017732.
HOGENOM	HBG744556.
OMA	ALTHKSF.
ProtClustDB	PRK00102.
Family and domain databases
HAMAP	MF_00104. RNase_III. [Tree]
InterPro	IPR001159. Ds-RNA-bd. IPR014720. dsRNA-bd-like. IPR000999. RNase_III. IPR011907. RNase_III_bac. [Graphical view]
Gene3D	G3DSA:3.30.160.20. dsRNA-bd-like. 1 hit. G3DSA:1.10.1520.10. RNase_III. 1 hit.
KO	K03685.
PANTHER	PTHR11207. PTHR11207. 1 hit.
Pfam	PF00035. dsrm. 1 hit. PF00636. Ribonuclease_3. 1 hit. [Graphical view]
SMART	SM00358. DSRM. 1 hit. SM00535. RIBOc. 1 hit. [Graphical view]
SUPFAM	SSF69065. RNase_III. 1 hit.
TIGRFAMs	TIGR02191. RNaseIII. 1 hit.
PROSITE	PS50137. DS_RBD. 1 hit. PS00517. RNASE_3_1. 1 hit. PS50142. RNASE_3_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B1MDL3_MYCA9

Accession

Primary (citable) accession number: B1MDL3

Entry history

Integrated into UniProtKB/TrEMBL:	April 29, 2008
Last sequence update:	April 29, 2008
Last modified:	December 14, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)