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B1MDF1 (EFTS_MYCA9) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Elongation factor Ts
Short name=EF-Ts
Gene names
Name:tsf
Ordered Locus Names:MAB_3195c
OrganismMycobacterium abscessus (strain ATCC 19977 / DSM 44196) [Complete proteome] [HAMAP]
Taxonomic identifier561007 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium abscessus

Protein attributes

Sequence length277 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome By similarity. HAMAP MF_00050

Subcellular location

Cytoplasm By similarity HAMAP MF_00050.

Sequence similarities

Belongs to the EF-Ts family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   Molecular functionElongation factor
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functiontranslation elongation factor activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 277277Elongation factor Ts HAMAP MF_00050
PRO_1000116762

Regions

Region76 – 794Involved in Mg(2+) ion dislocation from EF-Tu By similarity

Sequences

Sequence LengthMass (Da)Tools
B1MDF1 [UniParc].

Last modified April 29, 2008. Version 1.
Checksum: 01A1DC9A4F25CAED

FASTA27729,164
        10         20         30         40         50         60 
MANFTAADVK RLRELTGAGM LDCKNALAES DGDFDKAVEV LRIKGAKDVG KRAERATAEG 

        70         80         90        100        110        120 
LVVARDGALV ELNSETDFVA KNAEFQALAD AIVGAAAAGK IGEVDALLAA KVEDGRTVEQ 

       130        140        150        160        170        180 
AIADLAAKIG EKLELRRVAY FGGTVEAYLH KRAADLPPAV GVLVEYESAS GDATGADAAH 

       190        200        210        220        230        240 
AVALQIAALK AKYLTREDVP ADVVENERRI AEETAKAEGK PEAALPKIVE GRVTGYYKDV 

       250        260        270 
VLLDQPSVSD NKKSVKALLD EAGVTVTRFA RFEVGQA

« Hide

References

[1]"Acquisition of foreign virulence genes by the cystic fibrosis pathogen Mycobacterium abscessus."
Genoscope
Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L., Gaillard J.L.
Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 19977 / DSM 44196.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CU458896 Genomic DNA. Translation: CAM63272.1.
RefSeqYP_001703926.1. NC_010397.1.

3D structure databases

ProteinModelPortalB1MDF1.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1MDF1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000008879; EBMYCP00000008818; EBMYCG00000008877.
GeneID5965700.
GenomeReviewsGene locus MAB_3195c in contig CU458896_GR.
KEGGmab:MAB_3195c.
PATRIC17978160. VBIMycAbs55940_3253.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000016347.
HOGENOMHBG713289.
OMAYLHGTRI.
ProtClustDBPRK09377.

Enzyme and pathway databases

BioCycMABS561007:MAB_3195C-MONOMER.

Family and domain databases

HAMAPMF_00050. EF_Ts.
[Tree]
InterProIPR001816. Transl_elong_EFTs/EF1B.
IPR014039. Transl_elong_EFTs/EF1B_dimer.
IPR018101. Transl_elong_Ts_CS.
IPR009060. UBA-like.
IPR000449. UBA/transl_elong_EF1B_N.
[Graphical view]
Gene3DG3DSA:3.30.479.20. Transl_elong_EFTs/EF1B_dimer. 3 hits.
KOK02357.
PANTHERPTHR11741. Transl_elong_EFTs/EF1B. 1 hit.
PfamPF00889. EF_TS. 1 hit.
PF00627. UBA. 1 hit.
[Graphical view]
SUPFAMSSF54713. EF_TS. 1 hit.
SSF46934. UBA_like. 1 hit.
TIGRFAMsTIGR00116. Tsf. 1 hit.
PROSITEPS01126. EF_TS_1. 1 hit.
PS01127. EF_TS_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameEFTS_MYCA9
AccessionPrimary (citable) accession number: B1MDF1
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 29, 2008
Last modified: January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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