B1MD56 (B1MD56_MYCA9) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine dehydrogenase PIRNR PIRNR000183
EC=1.4.1.1 PIRNR PIRNR000183

Gene names

Ordered Locus Names:

MAB_3100

Organism

Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) [Complete proteome] [HAMAP]

Taxonomic identifier

561007 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium abscessus

Protein attributes

Sequence length	371 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH. PIRNR PIRNR000183
Pathway	Amino-acid degradation; L-alanine degradation via dehydrogenase pathway; NH(3) and pyruvate from L-alanine: step 1/1. PIRNR PIRNR000183
Sequence similarities	Belongs to the AlaDH/PNT family. PIRNR PIRNR000183

Ontologies

Keywords
Ligand	NAD PIRNR PIRNR000183
Molecular function	Oxidoreductase PIRNR PIRNR000183
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	alanine dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1MD56 [UniParc]. Last modified April 29, 2008. Version 1. Checksum: B4C7144274F5967F	FASTA	371	38,705
	10 20 30 40 50 60 MRVGIPTEIK NNEYRVATTP AGVAELTRRG HEVIIQSGAG DGSSISDVDF KAAGAQVING 70 80 90 100 110 120 AEQVWAEADL LLKVKEPIEP EYALMRRGQT LFTYLHLAAS LPCTQALLKS ETTSIAYETV 130 140 150 160 170 180 QTSDGALPLL APMSEVAGRL AAQVGAYHLM TPVGGRGLVM GGVPGVGPAD VVVIGGGVAG 190 200 210 220 230 240 YNAARIAAGM GAHVTVFDVN LGKLRELDGE FGGTIRTRYS STMELEGAVK RADLVIGAVL 250 260 270 280 290 300 IPGAKAPKLI SNSLVSQMKP GSVLVDIAID QGGCFADSRP TTHDEPTYTV HDSVFYCVAN 310 320 330 340 350 360 MPGAVPRTST FALTNATMPY VLALADKGWR QACRDDAALA QGLSTHEGAL LNTHVAHDLG 370 LAFTDPAEVL G

References

[1]

"Acquisition of foreign virulence genes by the cystic fibrosis pathogen Mycobacterium abscessus." Genoscope Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L., Gaillard J.L. Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU458896 Genomic DNA. Translation: CAM63177.1.
RefSeq	YP_001703831.1. NC_010397.1.
3D structure databases
ProteinModelPortal	B1MD56.
SMR	B1MD56. Positions 1-371.
ModBase	Search...
Protein-protein interaction databases
STRING	B1MD56.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000007197; EBMYCP00000007136; EBMYCG00000007195.
GeneID	5965606.
GenomeReviews	Gene locus MAB_3100 in contig CU458896_GR.
KEGG	mab:MAB_3100.
PATRIC	17977956. VBIMycAbs55940_3151.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000016024.
HOGENOM	HBG289735.
OMA	RGHEVII.
ProtClustDB	CLSK792072.
Family and domain databases
InterPro	IPR008142. Ala_DH/PNT_CS1. IPR008143. Ala_DH/PNT_CS2. IPR008141. Ala_DH/Pyr_transHydgase. IPR007886. AlaDH/PNT_N. IPR007698. AlaDH/PNT_NAD(H)-bd. [Graphical view]
KO	K00259.
PANTHER	PTHR10160:SF3. PTHR10160:SF3. 1 hit.
Pfam	PF01262. AlaDh_PNT_C. 1 hit. PF05222. AlaDh_PNT_N. 1 hit. [Graphical view]
PIRSF	PIRSF000183. Alanine_dh. 1 hit.
SMART	SM01002. AlaDh_PNT_C. 1 hit. SM01003. AlaDh_PNT_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR00518. AlaDH. 1 hit.
PROSITE	PS00836. ALADH_PNT_1. 1 hit. PS00837. ALADH_PNT_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B1MD56_MYCA9

Accession

Primary (citable) accession number: B1MD56

Entry history

Integrated into UniProtKB/TrEMBL:	April 29, 2008
Last sequence update:	April 29, 2008
Last modified:	January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)